Patents by Inventor Jean-Luc Battini

Jean-Luc Battini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of receptor-binding domain derived from bovine leukemia virus for the diagnosis or treatment of cationic l-amino acid transporter-related diseases
    Patent number: 11573240
    Abstract: Disclosed are methods for diagnosing CAT1-related diseases, wherein the methods include detecting CAT1 in a cell by a BLV.RBD ligand, or a variant or a fragment thereof. Also disclosed is a BLV.RBD ligand, or a variant or a fragment thereof for use in the treatment of CAT1-related diseases and/or BLV infections.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: February 7, 2023
    Assignees: METAFORA BIOSYSTEMS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE MONTPELLIER, UNIVERSITÉ PARIS CITÉ
    Inventors: Svilena Ivanova, Donatella Giovannini, Julien Bellis, Jawida Lezaar, Vincent Petit, Jean-Luc Battini, Marc Sitbon, Valérie Courgnaud
  • USE OF LIGANDS DERIVED FROM RECEPTOR-BINDING DOMAIN OF PORCINE ENDOGENOUS RETROVIRUS TYPE B FOR DIAGNOSING SMVT-RELATED DISEASES
    Publication number: 20220003782
    Abstract: Methods for detecting and/or measuring the level of sodium-dependent multivitamin transporter (SMVT) in a biological sample. The methods include the steps of: (a) contacting the biological sample with a PERV-B.RBD ligand, a variant and/or a fragment thereof; and, detecting and/or measuring the binding of the PERV-B.RBD ligand, variant and/or fragment thereof to SMVT.
    Type: Application
    Filed: October 7, 2019
    Publication date: January 6, 2022
    Applicants: METAFORA BIOSYSTEMS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE MONTPELLIER, UNIVERSITÉ DE PARIS
    Inventors: Marc SITBON, Vincent PETIT, Svilena IVANOVA, Jean-Luc BATTINI, Valérie COURGNAUD, Donatella GIOVANNINI, Jawida LEZAAR
  • USE OF RECEPTOR-BINDING DOMAIN DERIVED FROM BOVINE LEUKEMIA VIRUS FOR THE DIAGNOSIS OR TREATMENT OF CATIONIC L-AMINO ACID TRANSPORTER-RELATED DISEASES
    Publication number: 20180335435
    Abstract: Disclosed are methods for diagnosing CAT1-related diseases, wherein the methods include detecting CAT1 in a cell by a BLV.RBD ligand, or a variant or a fragment thereof. Also disclosed is a BLV.RBD ligand, or a variant or a fragment thereof for use in the treatment of CAT1-related diseases and/or BLV infections.
    Type: Application
    Filed: November 18, 2016
    Publication date: November 22, 2018
    Inventors: Svilena IVANOVA, Donatella GIOVANNINI, Julien BELLIS, Jawida LEZAAR, Vincent PETIT, Jean-Luc BATTINI, Marc SITBON, Valérie COURGNAUD
  • RECEPTOR-BINDING DOMAINS LIGANDS FOR THE DETECTION, DIAGNOSIS AND TREATMENT OF PANCREATIC CANCER
    Publication number: 20180280549
    Abstract: Disclosed are methods for diagnosing pancreatic cancer, including measuring the expression level of ASCT1 and/or ASCT2 and/or XPR1. Also disclosed is a RBD ligand coupled to at least one contrast agent, that may be used as a probe for medical imaging.
    Type: Application
    Filed: October 5, 2016
    Publication date: October 4, 2018
    Applicants: METAFORA BIOSYSTEMS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE MONTPELLIER, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)
    Inventors: Jawida TOUHAMI, Guangqi E, Donatella GIOVANNINI, Bruno ROBERT, Samuel SEVESTRE, Muriel BUSSON, Jean-Luc BATTINI, Vincent PETIT, Marc SITBON
  • GLUT-1 AS A RECEPTOR FOR HTLV ENVELOPES AND ITS USES
    Publication number: 20180002383
    Abstract: The present application relates to a method for diagnosing a glucose transporter type 1 (GLUT1) deficiency syndrome that utilizes polypeptides derived from the soluble part of the glycoprotein of the enveloped virus of primate T-cell leukemia virus (PTLV). The polypeptides, named receptor binding domain ligands (RBD), are selected for their ability to bind specifically to GLUT1. The method involves determining the level of GLUT 1 expression at the cell surface and comparing the level to a reference value.
    Type: Application
    Filed: September 8, 2017
    Publication date: January 4, 2018
    Inventors: Jean-Luc BATTINI, Nicolas MANEL, Felix KIM, Sandrina KINET, Naomi TAYLOR, Marc SITBON
  • Receptor binding ligands, their use in the detection of cells with biological interest
    Patent number: 9791435
    Abstract: A method for the identification and quantification of the expression of membrane receptors present on the surface of target cells using at least two soluble receptor binding ligands derived from the soluble part of the glycoprotein of an enveloped virus that interacts with a cellular cognate receptor, the receptor binding ligand containing a part or the totality of one of the receptor binding domains (RBD) of the glycoprotein, and the soluble receptor binding ligand being liable to interact with the at least one membrane receptor of a target cell, for the identification and quantification of the expression of membrane receptors present on the surface of target cells, the identification and quantification taking place at a given time or during a given time interval, and allowing the determination of a physiological state of the target cell.
    Type: Grant
    Filed: January 8, 2010
    Date of Patent: October 17, 2017
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE MONTPELLIER 2
    Inventors: Marc Sitbon, Jean-Luc Battini, Naomi Taylor, Cedric Mongellaz
  • GLUT-1 as a receptor for HTLV envelopes and its uses
    Patent number: 9777044
    Abstract: The present application relates to polypeptides derived from the soluble part of the glycoprotein of the enveloped virus of Primate T-cell leukemia virus (PTLV), or fragments or variants thereof named receptor binding domain ligands (RBD) selected for their ability to bind specifically to the nutrient transporter GLUT1.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: October 3, 2017
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE MONTPELLIER 2
    Inventors: Jean-Luc Battini, Nicolas Manel, Felix Kim, Sandrina Kinet, Naomi Taylor, Marc Sitbon
  • Method for the diagnosis and/or prognosis of granulocyte-related inflammatory states
    Patent number: 9157912
    Abstract: A method for the diagnosis and/or prognosis of inflammatory states, and the use of at least one soluble receptor-binding (RBD), for the identification and quantification of the expression of membrane receptors present on the surface of target granulocytes, said identification and quantification taking place at a given time or during a given time interval, and allowing the diagnosis and/or prognosis of inflammatory states in a mammal.
    Type: Grant
    Filed: September 19, 2011
    Date of Patent: October 13, 2015
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES, STANFORD UNIVERSITY
    Inventors: Rabindra Tirouvanziam, Julie Laval, Jean-Luc Battini, Marc Sitbon
  • GLUT-1 AS A RECEPTOR FOR HTLV ENVELOPES AND ITS USES
    Publication number: 20150133363
    Abstract: The present application relates to polypeptides derived from the soluble part of the glycoprotein of the enveloped virus of Primate T-cell leukemia virus (PTLV), or fragments or variants thereof named receptor binding domain ligands (RBD) selected for their ability to bind specifically to the nutrient transporter GLUT1.
    Type: Application
    Filed: December 18, 2014
    Publication date: May 14, 2015
    Inventors: Jean-Luc BATTINI, Nicolas MANEL, Felix KIM, Sandrina KINET, Naomi TAYLOR, Marc SITBON
  • PROCESS OF DIAGNOSTIC, PROGNOSTIC AND THERAPEUTIC MONITORING OF SOLID TUMORS
    Publication number: 20150099653
    Abstract: A process of diagnostic, prognostic and therapeutic monitoring of solid tumors, and new biological markers of tumor.
    Type: Application
    Filed: October 29, 2012
    Publication date: April 9, 2015
    Inventors: Jean-Luc Battini, Didier Decaudin, Gerald Massonnet, Vincent Petit, Marc Sitbon
  • METHOD FOR THE DIAGNOSIS AND/OR PROGNOSIS OF INFLAMMATORY STATES
    Publication number: 20130260394
    Abstract: The invention relates to a method for the diagnosis and/or prognosis of inflammatory states.
    Type: Application
    Filed: September 17, 2010
    Publication date: October 3, 2013
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Rabindra Tirouvanziam, Julie Laval, Jean-Luc Battini, Marc Sitbon
  • METHOD FOR THE DIAGNOSIS AND/OR PROGNOSIS OF INFLAMMATORY STATES
    Publication number: 20130252251
    Abstract: A method for the diagnosis and/or prognosis of inflammatory states, and the use of at least one soluble receptor-binding (RBD), for the identification and quantication of the expression of membrane receptors present on the surface of target granulocytes, said identification and quantification taking place at a given time or during a given time interval, and allowing the diagnosis and/or prognosis of inflammatory states in a mammal.
    Type: Application
    Filed: September 19, 2011
    Publication date: September 26, 2013
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, STANFORD UNIVERSITY, UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES
    Inventors: Rabindra Tirouvanziam, Julie Laval, Jean-Luc Battini, Marc Sitbon
  • NEW RECEPTOR BINDING LIGANDS, THEIR USE IN THE DETECTION OF CELLS WITH BIOLOGICAL INTEREST
    Publication number: 20130203080
    Abstract: A method for the identification and quantification of the expression of membrane receptors present on the surface of target cells using at least two soluble receptor binding ligands derived from the soluble part of the glycoprotein of an enveloped virus that interacts with a cellular cognate receptor, the receptor binding ligand containing a part or the totality of one of the receptor binding domains (RBD) of the glycoprotein, and the soluble receptor binding ligand being liable to interact with the at least one membrane receptor of a target cell, for the identification and quantification of the expression of membrane receptors present on the surface of target cells, the identification and quantification taking place at a given time or during a given time interval, and allowing the determination of a physiological state of the target cell.
    Type: Application
    Filed: January 8, 2010
    Publication date: August 8, 2013
    Applicants: UNIVERSITE MONTPELLIER 2, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Marc Sitbon, Jean-Luc Battini, Naomi Taylor, Cedric Mongellaz