Patents by Inventor Jean-Luc Gennisson
Jean-Luc Gennisson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11508261Abstract: The invention relates to a method for obtaining a numerical model, the numerical model associating at least one objective measurement to a subjective sensation, the method comprising the steps of: a) imaging the at least one area of the brain by using unfocused waves produced by a transcranial ultrasound probe (20), to obtain at least one acquired image of the activity of the area, b) evaluating a physical quantity representative of the activity of the at least one area based on the acquired images, to obtain at least one objective measurement, c) obtaining from the subject at least one numerical value representative of a subjective sensation, and d) determining the numerical model by using the obtained objective measurement and the obtained numerical value.Type: GrantFiled: September 23, 2016Date of Patent: November 22, 2022Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), Centre National de la recherche scientifique, Université Pierre et Marie Curie, Université Paris Diderot, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARISInventors: Thomas Deffieux, Mickaël Tanter, Jean-Luc Gennisson, Zsolt Lenkei, Mathieu Pernot
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Patent number: 11399804Abstract: A method for characterizing an anisotropic soft medium (C) including fibers and having an outer surface (1), by observing in different propagation directions, the propagation of a divergent shear wave from a central area (10) in the anisotropic soft medium. A propagation parameter of the shear wave is inferred therefrom in each of the propagation directions, and then a direction of the fibers of the anisotropic soft medium, a rheological elasticity parameter are determined in a direction perpendicular to the fibers and a rheological elasticity parameter in the direction of the fibers.Type: GrantFiled: January 12, 2015Date of Patent: August 2, 2022Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), ECOLE SUPRERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, UNIVERSITÉ PARIS DIDEROT—PARIS 7Inventors: Mickaël Tanter, Mathieu Pernot, Mathias Fink, Jean-Luc Gennisson
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Publication number: 20220039776Abstract: The invention concerns a multi-sensor brain detecting apparatus, the detecting apparatus being adapted to obtain two different physical values of a brain of a subject, the detecting apparatus comprising: a set of sensors comprising an ultrasound transducer adapted to produce ultrasound waves, a frame with a position with relation to the brain known with a stereotaxic precision, the frame being adapted to hold a sensor that can be positioned at a specific location by a user of the detecting apparatus without using a tool.Type: ApplicationFiled: October 21, 2021Publication date: February 10, 2022Inventors: Jean-Luc GENNISSON, Mickaël TANTER, Thomas DEFFIEUX, Mathieu PERNOT
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Patent number: 11234677Abstract: The invention concerns a detecting apparatus (12) comprising:—at least two sensors (24, 26, 28), with at least one sensor (24) being an ultrasound transducer adapted to produce ultrasound waves, and—a positioning device (16) defining several compartments (22), each compartment (22) being adapted to hold a sensor (24, 26, 28) and each compartment (22) being located at predetermined location, the positioning device (16) comprising a holder adapted to be fixed on the skull of a subject, the positioning device (16) being adapted to be maintained on the head of the subject using the holder.Type: GrantFiled: June 9, 2016Date of Patent: February 1, 2022Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie (Paris 6), Université Paris Diderot—Pris 7, Ecole Superieure de Physique et de Chimie Industrielles de la Ville de ParisInventors: Jean-Luc Gennisson, Mickaël Tanter, Thomas Deffieux, Mathieu Pernot
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Publication number: 20210361169Abstract: An acousto-optic imaging method in which light waves and unfocused acoustic waves having various directions of propagation m are emitted in a medium, by spatially modulating the amplitude of the ultrasonic transducers of an array of transducers according to several periodic spatial amplitude modulations j, and the resulting optical signal Smj(t) is captured. For each direction of propagation m, the signals Smj(t) are spatially demodulated in order to determine a signal Sm(t) used to reconstruct the image of the medium.Type: ApplicationFiled: March 11, 2019Publication date: November 25, 2021Applicants: Centre National de la Recherche Scientifique, ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, SORBONNE UNIVERSITE, UNIV PARIS XIII PARIS-NORD VILLETANEUSEInventors: François Ramaz, Jean-Luc Gennisson, Jean-Baptiste Laudereau, Clément Dupuy, Jean-Michel Tualle
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Publication number: 20210267495Abstract: A method for measuring diaphragmatic functional parameters, including: a) stimulation of the diaphragm to generate a movement of the diaphragm, b) during the movement of the diaphragm, imaging the diaphragm over time including the steps of emitting unfocused ultrasound waves, detecting ultrasound waves reflected and/or scattered by organic tissues, processing the reflected and/or scattered ultrasound waves over time, c) processing, images to measure movements of the diaphragm over time, and/or a propagation of a movement through the diaphragm over time, and/or a propagation speed of a movement through the diaphragm over time, and/or one or more movements of different parts of the diaphragm over time, and/or an amplitude of a movement of the diaphragm over time, and/or a time separating the stimulation of the diaphragm from the occurrence of a movement of the diaphragm associated to the stimulation, d) based on the measurements, determining functional parameters.Type: ApplicationFiled: September 13, 2019Publication date: September 2, 2021Inventors: Damien BACHASSON, Jean-Yves HOGREL, Martin DRES, Jean-Luc GENNISSON, Thomas SIMILOWSKI
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Patent number: 10955535Abstract: According to the invention, n incident acoustic waves Ei(t), obtained by linearly combining n elemental incident waves E0i(t) with an encoding matrix Hc are consecutively transmitted in a medium to be imaged. n reverberated waves Ri(t) from the medium to be imaged are then consecutively detected, following the transmission of the n incident waves; then n elemental reverberated waves R0i(t) are determined by linearly combining the detected n reverberated waves Ri(t) with a decoding matrix Hd. The Hc and Hd matrices are such that Hc·Hd=D, where D is a diagonal matrix of order n, all the diagonal elements of which are greater than 1.Type: GrantFiled: September 25, 2015Date of Patent: March 23, 2021Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSERMInventors: Mickaël Tanter, Bruno-Félix Osmanski, Mathieu Pernot, Jean-Luc Gennisson
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Patent number: 10952701Abstract: The invention concerns a detecting apparatus (12) for imaging at least two areas of a brain of a subject (10), the detecting apparatus (12) comprising: —a holder comprising: —a frame (14) devoted to be cemented on the skull of the subject (10), the frame (14) delimitating an inner portion (18) which is transparent to ultrasound waves, —a removable imaging device comprising: —a platform (16) delimitating an inner space (28), the inner space (28) facing the inner portion (18), —a fixing element (30) adapted to temporary fix and lock the platform (16) to the holder, —an ultrasound probe (32), and —a moving stage (34) holding the ultrasound probe (32) and being adapted to move the ultrasound probe (32) within the inner space (28).Type: GrantFiled: June 16, 2016Date of Patent: March 23, 2021Assignees: INSTITUT NATIONAL DE LA SANTE ET DE RECHERCHE MEDICAL (INSERM), UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), UNIVERSITE PARIS DIDEROT—PARIS 7, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARISInventors: Thomas Deffieux, Jean-Luc Gennisson, Mickaël Tanter, Ivan Cohen, Mathieu Pernot
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Patent number: 10653387Abstract: Method for functional imaging of the brain, comprising the following steps: (a) a brain is imaged by ultrasound imaging in order to obtain a vascular image to be studied (IVO), (b) the vascular image to be studied (IVO) is compared automatically, by shape recognition, with a cerebral vascular atlas (AV), and the vascular image to be studied (IVO) is thus located in the cerebral vascular atlas (AV), (c) a cerebral functional atlas (AF) corresponding to said cerebral vascular atlas (AV) and comprising cerebral functional zones (1c) located in this cerebral vascular atlas (AV) is used in such a way as to identify cerebral functional zones (1e) on the vascular image to be studied (IVO).Type: GrantFiled: June 29, 2015Date of Patent: May 19, 2020Assignees: INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ÉCOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, UNIVERSITÉ PIERRE ET MARIE CURIE (PARIS 6), UNIVERSITÉ PARIS DIDEROT—PARIS 7Inventors: Mickaél Tanter, Jean-luc Gennisson, Thomas Deffieux, Mathieu Pernot
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Patent number: 10603013Abstract: A method for measuring a mean visco-elasticity value for a soft material uses a single probe carrying at least one transducer. At least one burst of mechanical vibrations is induced in a constraint zone in order to generate internal shear waves in the tissue propagating from the constraint zone into the tissue. The transient tissue displacements are measured with a transducer in at least one first measurement zone in the tissue, the first measurement zone being located away from the constraint zone. A mean visco-elasticity of the region of the tissue situated between the constraint zone and the first measurement zone is estimated from the measured transient tissue displacements of the tissue in the first measurement zone.Type: GrantFiled: September 27, 2013Date of Patent: March 31, 2020Assignee: Super Sonic ImagineInventors: Jeremy Bercoff, David Savery, Mickael Tanter, Jean-Luc Gennisson, Mathias Fink, Claude Cohen-Bacrie
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Patent number: 10172527Abstract: Method for measuring a physical parameter in soft tissues of a mammal, in which a mechanical shear wave is propagated through the soft tissues and observation of the propagation leads to determine values of a shear wave propagation parameter. The physical parameter is computed on the basis of these values.Type: GrantFiled: July 31, 2009Date of Patent: January 8, 2019Assignees: Supersonic Imagine, Centre National de la Recherche Scientifique—CNRS, Institut National De La Santé Et De La Recherche Médicale, Université Paris Diderot-Paris 7Inventors: Mathieu Pernot, Mickael Tanter, Mathieu Couade, Jean-Luc Gennisson, Mathias Fink
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Publication number: 20180261127Abstract: The invention relates to a method for obtaining a numerical model, the numerical model associating at least one objective measurement to a subjective sensation, the method comprising the steps of: a) imaging the at least one area of the brain by using unfocused waves produced by a transcranial ultrasound probe (20), to obtain at least one acquired image of the activity of the area, b) evaluating a physical quantity representative of the activity of the at least one area based on the acquired images, to obtain at least one objective measurement, c) obtaining from the subject at least one numerical value representative of a subjective sensation, and d) determining the numerical model by using the obtained objective measurement and the obtained numerical value.Type: ApplicationFiled: September 23, 2016Publication date: September 13, 2018Inventors: Thomas DEFFIEUX, Mickaël TANTER, Jean-Luc GENNISSON, Zsolt LENKEI, Mathieu PERNOT
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Publication number: 20180217051Abstract: The invention relates to an acoustic-optical imaging method and system of a zone for observing an environment. The system includes an acquisition device comprising, a network of transducers for generating a plurality of non-focussed sound waves, a light-emitting device for emitting an incident light wave and generating marked light waves comprising an acoustic-optical component that is shifted in frequency by the non-focussed sound waves, and a detector for acquiring measurement signals. The system also comprises a processing device for determining a light intensity in the observation zone from the measurement signals.Type: ApplicationFiled: June 2, 2015Publication date: August 2, 2018Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE- INSERMInventors: François Ramaz, Mickaël Tanter, Jean-Baptiste Laudereau, Jean-Luc Gennisson
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Publication number: 20180177487Abstract: The invention concerns a detecting apparatus (12) for imaging at least two areas of a brain of a subject (10), the detecting apparatus (12) comprising:—a holder comprising:—a frame (14) devoted to be cemented on the skull of the subject (10), the frame (14) delimitating an inner portion (18) which is transparent to ultrasound waves,—a removable imaging device comprising:—a platform (16) delimitating an inner space (28), the inner space (28) facing the inner portion (18),—a fixing element (30) adapted to temporary fix and lock the platform (16) to the holder,—an ultrasound probe (32), and—a moving stage (34) holding the ultrasound probe (32) and being adapted to move the ultrasound probe (32) within the inner space (28).Type: ApplicationFiled: June 16, 2016Publication date: June 28, 2018Inventors: Thomas DEFFIEUX, Jean-Luc GENNISSON, Mickaël TANTER, Ivan COHEN, Mathieu PERNOT
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Publication number: 20180153507Abstract: The invention concerns a detecting apparatus (12) comprising:—at least two sensors (24, 26, 28), with at least one sensor (24) being an ultrasound transducer adapted to produce ultrasound waves, and—a positioning device (16) defining several compartments (22), each compartment (22) being adapted to hold a sensor (24, 26, 28) and each compartment (22) being located at predetermined location, the positioning device (16) comprising a holder adapted to be fixed on the skull of a subject, the positioning device (16) being adapted to be maintained on the head of the subject using the holder.Type: ApplicationFiled: June 9, 2016Publication date: June 7, 2018Inventors: Jean-Luc GENNISSON, Mickaël TANTER, Thomas DEFFIEUX, Mathieu PERNOT
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Publication number: 20170276775Abstract: According to the invention, n incident acoustic waves Ei(t), obtained by linearly combining n elemental incident waves E0i(t) with an encoding matrix Hc are consecutively transmitted in a medium to be imaged. n reverberated waves Ri(t) from the medium to be imaged are then consecutively detected, following the transmission of the n incident waves; then n elemental reverberated waves R0i(t) are determined by linearly combining the detected n reverberated waves Ri(t) with a decoding matrix Hd. The Hc and Hd matrices are such that Hc.Hd=D, where D is a diagonal matrix of order n, all the diagonal elements of which are greater than 1.Type: ApplicationFiled: September 25, 2015Publication date: September 28, 2017Applicants: CENTRE NATIONAL DE LA RE-CHERCHE SCIENTIFIQUE-CNRS, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DEInventors: Mickaël Tanter, Bruno-Félix Osmanski, Mathieu Pernot, Jean-Luc Gennisson
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Publication number: 20170128036Abstract: Method for functional imaging of the brain, comprising the following steps: (a) a brain is imaged by ultrasound imaging in order to obtain a vascular image to be studied (IVO), (b) the vascular image to he studied (IVO) is compared automatically, by shape recognition, with a cerebral vascular atlas (AV), and the vascular image to be studied (IVO) is thus located in the cerebral vascular atlas (AV), (c) a cerebral functional atlas (AF) corresponding to said cerebral vascular atlas (AV) and comprising cerebral functional zones (1c) located in this cerebral vascular atlas (AV) is used in such a way as to identify cerebral functional zones (1e) on the vascular image to be studied (IVO).Type: ApplicationFiled: June 29, 2015Publication date: May 11, 2017Inventors: Mickaël TANTER, Jean-luc GENNISSON, Thomas DEFFIEUX, Mathieu PERNOT
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Publication number: 20160345938Abstract: A method for characterizing an anisotropic soft medium (C) including fibers and having an outer surface (1), by observing in different propagation directions, the propagation of a divergent shear wave from a central area (10) in the anisotropic soft medium. A propagation parameter of the shear wave is inferred therefrom in each of the propagation directions, and then a direction of the fibers of the anisotropic soft medium, a rheological elasticity parameter are determined in a direction perpendicular to the fibers and a rheological elasticity parameter in the direction of the fibers.Type: ApplicationFiled: January 12, 2015Publication date: December 1, 2016Inventors: Mickaël TANTER, Mathieu PERNOT, Mathias FINK, Jean-Luc GENNISSON
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Publication number: 20140081138Abstract: The invention relates to a method for measuring a mean visco-elasticity value for a soft material. Said method using a single probe carrying at least one transducer comprises the steps of: a) inducing, in a constraint zone, at least one burst of mechanical vibrations in order to generate internal shear waves in the tissue propagating from said constraint zone into the tissue, b1) measuring, with said transducer, the transient tissue displacements in at least one first measurement zone in the tissue, said first measurement zone being located away from said constraint zone, c) estimating a mean visco-elasticity of the region of the tissue situated between the constraint zone and the first measurement zone from said measured transient tissue displacements of the tissue in the first measurement zone.Type: ApplicationFiled: September 27, 2013Publication date: March 20, 2014Applicant: SUPER SONIC IMAGINEInventors: Jeremy BERCOFF, David SAVERY, Mickael TANTER, Jean-Luc GENNISSON, Mathias FINK, Claude COHEN-BACRIE
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Patent number: 8545407Abstract: The invention relates to a method for measuring a mean visco-elasticity value for a soft material. The method uses a single probe carrying at least one transducer and includes the steps of: (a) inducing, in a constraint zone, at least one burst of mechanical vibrations in order to generate internal shear waves in the tissue propagating from the constraint zone into the tissue, (b1) measuring, with the transducer, the transient tissue displacements in at least one first measurement zone in the tissue, and wherein the first measurement zone is located away from the constraint zone, and (c) estimating a mean visco-elasticity of the region of the tissue situated between the constraint zone and the first measurement zone from the measured transient tissue displacements of the tissue in the first measurement zone.Type: GrantFiled: May 16, 2007Date of Patent: October 1, 2013Assignees: Super Sonic Imagine, Centre National de la Recherche Scientifique (CNRS)Inventors: Jeremy Bercoff, David Savery, Mickaël Tanter, Jean-Luc Gennisson, Mathias Fink, Claude Cohen-Bacrie