Patents by Inventor Jean-Luc Gennisson

Jean-Luc Gennisson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11508261
    Abstract: The invention relates to a method for obtaining a numerical model, the numerical model associating at least one objective measurement to a subjective sensation, the method comprising the steps of: a) imaging the at least one area of the brain by using unfocused waves produced by a transcranial ultrasound probe (20), to obtain at least one acquired image of the activity of the area, b) evaluating a physical quantity representative of the activity of the at least one area based on the acquired images, to obtain at least one objective measurement, c) obtaining from the subject at least one numerical value representative of a subjective sensation, and d) determining the numerical model by using the obtained objective measurement and the obtained numerical value.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: November 22, 2022
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), Centre National de la recherche scientifique, Université Pierre et Marie Curie, Université Paris Diderot, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
    Inventors: Thomas Deffieux, Mickaël Tanter, Jean-Luc Gennisson, Zsolt Lenkei, Mathieu Pernot
  • Patent number: 11399804
    Abstract: A method for characterizing an anisotropic soft medium (C) including fibers and having an outer surface (1), by observing in different propagation directions, the propagation of a divergent shear wave from a central area (10) in the anisotropic soft medium. A propagation parameter of the shear wave is inferred therefrom in each of the propagation directions, and then a direction of the fibers of the anisotropic soft medium, a rheological elasticity parameter are determined in a direction perpendicular to the fibers and a rheological elasticity parameter in the direction of the fibers.
    Type: Grant
    Filed: January 12, 2015
    Date of Patent: August 2, 2022
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), ECOLE SUPRERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, UNIVERSITÉ PARIS DIDEROT—PARIS 7
    Inventors: Mickaël Tanter, Mathieu Pernot, Mathias Fink, Jean-Luc Gennisson
  • Publication number: 20220039776
    Abstract: The invention concerns a multi-sensor brain detecting apparatus, the detecting apparatus being adapted to obtain two different physical values of a brain of a subject, the detecting apparatus comprising: a set of sensors comprising an ultrasound transducer adapted to produce ultrasound waves, a frame with a position with relation to the brain known with a stereotaxic precision, the frame being adapted to hold a sensor that can be positioned at a specific location by a user of the detecting apparatus without using a tool.
    Type: Application
    Filed: October 21, 2021
    Publication date: February 10, 2022
    Inventors: Jean-Luc GENNISSON, Mickaël TANTER, Thomas DEFFIEUX, Mathieu PERNOT
  • Patent number: 11234677
    Abstract: The invention concerns a detecting apparatus (12) comprising:—at least two sensors (24, 26, 28), with at least one sensor (24) being an ultrasound transducer adapted to produce ultrasound waves, and—a positioning device (16) defining several compartments (22), each compartment (22) being adapted to hold a sensor (24, 26, 28) and each compartment (22) being located at predetermined location, the positioning device (16) comprising a holder adapted to be fixed on the skull of a subject, the positioning device (16) being adapted to be maintained on the head of the subject using the holder.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: February 1, 2022
    Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie (Paris 6), Université Paris Diderot—Pris 7, Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris
    Inventors: Jean-Luc Gennisson, Mickaël Tanter, Thomas Deffieux, Mathieu Pernot
  • Publication number: 20210361169
    Abstract: An acousto-optic imaging method in which light waves and unfocused acoustic waves having various directions of propagation m are emitted in a medium, by spatially modulating the amplitude of the ultrasonic transducers of an array of transducers according to several periodic spatial amplitude modulations j, and the resulting optical signal Smj(t) is captured. For each direction of propagation m, the signals Smj(t) are spatially demodulated in order to determine a signal Sm(t) used to reconstruct the image of the medium.
    Type: Application
    Filed: March 11, 2019
    Publication date: November 25, 2021
    Applicants: Centre National de la Recherche Scientifique, ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, SORBONNE UNIVERSITE, UNIV PARIS XIII PARIS-NORD VILLETANEUSE
    Inventors: François Ramaz, Jean-Luc Gennisson, Jean-Baptiste Laudereau, Clément Dupuy, Jean-Michel Tualle
  • Publication number: 20210267495
    Abstract: A method for measuring diaphragmatic functional parameters, including: a) stimulation of the diaphragm to generate a movement of the diaphragm, b) during the movement of the diaphragm, imaging the diaphragm over time including the steps of emitting unfocused ultrasound waves, detecting ultrasound waves reflected and/or scattered by organic tissues, processing the reflected and/or scattered ultrasound waves over time, c) processing, images to measure movements of the diaphragm over time, and/or a propagation of a movement through the diaphragm over time, and/or a propagation speed of a movement through the diaphragm over time, and/or one or more movements of different parts of the diaphragm over time, and/or an amplitude of a movement of the diaphragm over time, and/or a time separating the stimulation of the diaphragm from the occurrence of a movement of the diaphragm associated to the stimulation, d) based on the measurements, determining functional parameters.
    Type: Application
    Filed: September 13, 2019
    Publication date: September 2, 2021
    Inventors: Damien BACHASSON, Jean-Yves HOGREL, Martin DRES, Jean-Luc GENNISSON, Thomas SIMILOWSKI
  • Patent number: 10955535
    Abstract: According to the invention, n incident acoustic waves Ei(t), obtained by linearly combining n elemental incident waves E0i(t) with an encoding matrix Hc are consecutively transmitted in a medium to be imaged. n reverberated waves Ri(t) from the medium to be imaged are then consecutively detected, following the transmission of the n incident waves; then n elemental reverberated waves R0i(t) are determined by linearly combining the detected n reverberated waves Ri(t) with a decoding matrix Hd. The Hc and Hd matrices are such that Hc·Hd=D, where D is a diagonal matrix of order n, all the diagonal elements of which are greater than 1.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: March 23, 2021
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSERM
    Inventors: Mickaël Tanter, Bruno-Félix Osmanski, Mathieu Pernot, Jean-Luc Gennisson
  • Patent number: 10952701
    Abstract: The invention concerns a detecting apparatus (12) for imaging at least two areas of a brain of a subject (10), the detecting apparatus (12) comprising: —a holder comprising: —a frame (14) devoted to be cemented on the skull of the subject (10), the frame (14) delimitating an inner portion (18) which is transparent to ultrasound waves, —a removable imaging device comprising: —a platform (16) delimitating an inner space (28), the inner space (28) facing the inner portion (18), —a fixing element (30) adapted to temporary fix and lock the platform (16) to the holder, —an ultrasound probe (32), and —a moving stage (34) holding the ultrasound probe (32) and being adapted to move the ultrasound probe (32) within the inner space (28).
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: March 23, 2021
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE RECHERCHE MEDICAL (INSERM), UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), UNIVERSITE PARIS DIDEROT—PARIS 7, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
    Inventors: Thomas Deffieux, Jean-Luc Gennisson, Mickaël Tanter, Ivan Cohen, Mathieu Pernot
  • Patent number: 10653387
    Abstract: Method for functional imaging of the brain, comprising the following steps: (a) a brain is imaged by ultrasound imaging in order to obtain a vascular image to be studied (IVO), (b) the vascular image to be studied (IVO) is compared automatically, by shape recognition, with a cerebral vascular atlas (AV), and the vascular image to be studied (IVO) is thus located in the cerebral vascular atlas (AV), (c) a cerebral functional atlas (AF) corresponding to said cerebral vascular atlas (AV) and comprising cerebral functional zones (1c) located in this cerebral vascular atlas (AV) is used in such a way as to identify cerebral functional zones (1e) on the vascular image to be studied (IVO).
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: May 19, 2020
    Assignees: INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ÉCOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, UNIVERSITÉ PIERRE ET MARIE CURIE (PARIS 6), UNIVERSITÉ PARIS DIDEROT—PARIS 7
    Inventors: Mickaél Tanter, Jean-luc Gennisson, Thomas Deffieux, Mathieu Pernot
  • Patent number: 10603013
    Abstract: A method for measuring a mean visco-elasticity value for a soft material uses a single probe carrying at least one transducer. At least one burst of mechanical vibrations is induced in a constraint zone in order to generate internal shear waves in the tissue propagating from the constraint zone into the tissue. The transient tissue displacements are measured with a transducer in at least one first measurement zone in the tissue, the first measurement zone being located away from the constraint zone. A mean visco-elasticity of the region of the tissue situated between the constraint zone and the first measurement zone is estimated from the measured transient tissue displacements of the tissue in the first measurement zone.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: March 31, 2020
    Assignee: Super Sonic Imagine
    Inventors: Jeremy Bercoff, David Savery, Mickael Tanter, Jean-Luc Gennisson, Mathias Fink, Claude Cohen-Bacrie
  • Patent number: 10172527
    Abstract: Method for measuring a physical parameter in soft tissues of a mammal, in which a mechanical shear wave is propagated through the soft tissues and observation of the propagation leads to determine values of a shear wave propagation parameter. The physical parameter is computed on the basis of these values.
    Type: Grant
    Filed: July 31, 2009
    Date of Patent: January 8, 2019
    Assignees: Supersonic Imagine, Centre National de la Recherche Scientifique—CNRS, Institut National De La Santé Et De La Recherche Médicale, Université Paris Diderot-Paris 7
    Inventors: Mathieu Pernot, Mickael Tanter, Mathieu Couade, Jean-Luc Gennisson, Mathias Fink
  • Publication number: 20180261127
    Abstract: The invention relates to a method for obtaining a numerical model, the numerical model associating at least one objective measurement to a subjective sensation, the method comprising the steps of: a) imaging the at least one area of the brain by using unfocused waves produced by a transcranial ultrasound probe (20), to obtain at least one acquired image of the activity of the area, b) evaluating a physical quantity representative of the activity of the at least one area based on the acquired images, to obtain at least one objective measurement, c) obtaining from the subject at least one numerical value representative of a subjective sensation, and d) determining the numerical model by using the obtained objective measurement and the obtained numerical value.
    Type: Application
    Filed: September 23, 2016
    Publication date: September 13, 2018
    Inventors: Thomas DEFFIEUX, Mickaël TANTER, Jean-Luc GENNISSON, Zsolt LENKEI, Mathieu PERNOT
  • Publication number: 20180217051
    Abstract: The invention relates to an acoustic-optical imaging method and system of a zone for observing an environment. The system includes an acquisition device comprising, a network of transducers for generating a plurality of non-focussed sound waves, a light-emitting device for emitting an incident light wave and generating marked light waves comprising an acoustic-optical component that is shifted in frequency by the non-focussed sound waves, and a detector for acquiring measurement signals. The system also comprises a processing device for determining a light intensity in the observation zone from the measurement signals.
    Type: Application
    Filed: June 2, 2015
    Publication date: August 2, 2018
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE- INSERM
    Inventors: François Ramaz, Mickaël Tanter, Jean-Baptiste Laudereau, Jean-Luc Gennisson
  • Publication number: 20180177487
    Abstract: The invention concerns a detecting apparatus (12) for imaging at least two areas of a brain of a subject (10), the detecting apparatus (12) comprising:—a holder comprising:—a frame (14) devoted to be cemented on the skull of the subject (10), the frame (14) delimitating an inner portion (18) which is transparent to ultrasound waves,—a removable imaging device comprising:—a platform (16) delimitating an inner space (28), the inner space (28) facing the inner portion (18),—a fixing element (30) adapted to temporary fix and lock the platform (16) to the holder,—an ultrasound probe (32), and—a moving stage (34) holding the ultrasound probe (32) and being adapted to move the ultrasound probe (32) within the inner space (28).
    Type: Application
    Filed: June 16, 2016
    Publication date: June 28, 2018
    Inventors: Thomas DEFFIEUX, Jean-Luc GENNISSON, Mickaël TANTER, Ivan COHEN, Mathieu PERNOT
  • Publication number: 20180153507
    Abstract: The invention concerns a detecting apparatus (12) comprising:—at least two sensors (24, 26, 28), with at least one sensor (24) being an ultrasound transducer adapted to produce ultrasound waves, and—a positioning device (16) defining several compartments (22), each compartment (22) being adapted to hold a sensor (24, 26, 28) and each compartment (22) being located at predetermined location, the positioning device (16) comprising a holder adapted to be fixed on the skull of a subject, the positioning device (16) being adapted to be maintained on the head of the subject using the holder.
    Type: Application
    Filed: June 9, 2016
    Publication date: June 7, 2018
    Inventors: Jean-Luc GENNISSON, Mickaël TANTER, Thomas DEFFIEUX, Mathieu PERNOT
  • Publication number: 20170276775
    Abstract: According to the invention, n incident acoustic waves Ei(t), obtained by linearly combining n elemental incident waves E0i(t) with an encoding matrix Hc are consecutively transmitted in a medium to be imaged. n reverberated waves Ri(t) from the medium to be imaged are then consecutively detected, following the transmission of the n incident waves; then n elemental reverberated waves R0i(t) are determined by linearly combining the detected n reverberated waves Ri(t) with a decoding matrix Hd. The Hc and Hd matrices are such that Hc.Hd=D, where D is a diagonal matrix of order n, all the diagonal elements of which are greater than 1.
    Type: Application
    Filed: September 25, 2015
    Publication date: September 28, 2017
    Applicants: CENTRE NATIONAL DE LA RE-CHERCHE SCIENTIFIQUE-CNRS, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE
    Inventors: Mickaël Tanter, Bruno-Félix Osmanski, Mathieu Pernot, Jean-Luc Gennisson
  • Publication number: 20170128036
    Abstract: Method for functional imaging of the brain, comprising the following steps: (a) a brain is imaged by ultrasound imaging in order to obtain a vascular image to be studied (IVO), (b) the vascular image to he studied (IVO) is compared automatically, by shape recognition, with a cerebral vascular atlas (AV), and the vascular image to be studied (IVO) is thus located in the cerebral vascular atlas (AV), (c) a cerebral functional atlas (AF) corresponding to said cerebral vascular atlas (AV) and comprising cerebral functional zones (1c) located in this cerebral vascular atlas (AV) is used in such a way as to identify cerebral functional zones (1e) on the vascular image to be studied (IVO).
    Type: Application
    Filed: June 29, 2015
    Publication date: May 11, 2017
    Inventors: Mickaël TANTER, Jean-luc GENNISSON, Thomas DEFFIEUX, Mathieu PERNOT
  • Publication number: 20160345938
    Abstract: A method for characterizing an anisotropic soft medium (C) including fibers and having an outer surface (1), by observing in different propagation directions, the propagation of a divergent shear wave from a central area (10) in the anisotropic soft medium. A propagation parameter of the shear wave is inferred therefrom in each of the propagation directions, and then a direction of the fibers of the anisotropic soft medium, a rheological elasticity parameter are determined in a direction perpendicular to the fibers and a rheological elasticity parameter in the direction of the fibers.
    Type: Application
    Filed: January 12, 2015
    Publication date: December 1, 2016
    Inventors: Mickaël TANTER, Mathieu PERNOT, Mathias FINK, Jean-Luc GENNISSON
  • Publication number: 20140081138
    Abstract: The invention relates to a method for measuring a mean visco-elasticity value for a soft material. Said method using a single probe carrying at least one transducer comprises the steps of: a) inducing, in a constraint zone, at least one burst of mechanical vibrations in order to generate internal shear waves in the tissue propagating from said constraint zone into the tissue, b1) measuring, with said transducer, the transient tissue displacements in at least one first measurement zone in the tissue, said first measurement zone being located away from said constraint zone, c) estimating a mean visco-elasticity of the region of the tissue situated between the constraint zone and the first measurement zone from said measured transient tissue displacements of the tissue in the first measurement zone.
    Type: Application
    Filed: September 27, 2013
    Publication date: March 20, 2014
    Applicant: SUPER SONIC IMAGINE
    Inventors: Jeremy BERCOFF, David SAVERY, Mickael TANTER, Jean-Luc GENNISSON, Mathias FINK, Claude COHEN-BACRIE
  • Patent number: 8545407
    Abstract: The invention relates to a method for measuring a mean visco-elasticity value for a soft material. The method uses a single probe carrying at least one transducer and includes the steps of: (a) inducing, in a constraint zone, at least one burst of mechanical vibrations in order to generate internal shear waves in the tissue propagating from the constraint zone into the tissue, (b1) measuring, with the transducer, the transient tissue displacements in at least one first measurement zone in the tissue, and wherein the first measurement zone is located away from the constraint zone, and (c) estimating a mean visco-elasticity of the region of the tissue situated between the constraint zone and the first measurement zone from the measured transient tissue displacements of the tissue in the first measurement zone.
    Type: Grant
    Filed: May 16, 2007
    Date of Patent: October 1, 2013
    Assignees: Super Sonic Imagine, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Jeremy Bercoff, David Savery, Mickaël Tanter, Jean-Luc Gennisson, Mathias Fink, Claude Cohen-Bacrie