Patents by Inventor Jean-Luc Haesslein

Jean-Luc Haesslein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5691347
    Abstract: The bicyclic derivatives of pyridines of the formula ##STR1## and their non-toxic, pharmaceutically acceptable salts and a process and intermediates for their preparation which compounds are inhibitors of angiotensin II effects, particularly a vasoconstrictor activity.
    Type: Grant
    Filed: April 20, 1995
    Date of Patent: November 25, 1997
    Assignee: Roussel Uclaf
    Inventors: Alain Corbier, Michel Fortin, Jacques Guillaume, Jean-Luc Haesslein, Jean-Paul Vevert
  • Patent number: 5674883
    Abstract: Products of formula (I): ##STR1## in which: R.sub.1, R.sub.2, R.sub.3 and R.sub.4 represent:--a hydrogen atom, a halogen atom, one of the following radicals: hydroxyl, mercapto, cyano, nitro, sulpho, formyl, benzoyl, acyl, carboxy, cycloalkyl, acyloxy,--an alkyl, alkenyl, alkynyl, alkyloxy or alkythio radical,--an alkyl, alkenyl, alkynyl, alkyloxy or alkylthio radical,--an aryl, arylalkyl, arylalkenyl, aryloxy or arylthio radical,--a radical: ##STR2## --a--(CH.sub.2).sub.m1 --S(O).sub.m2 --Z'--R'.sub.14 radical in which m1 represents an integer from 0 to 4, m2 represents an integer from 0 to 2, R.sub.5 represents a divalent alkylene radical, Y represents the --Y.sub.1 --B--Y.sub.2 radical.These products have useful pharmacological properties, which justify their use as medicaments.
    Type: Grant
    Filed: July 31, 1996
    Date of Patent: October 7, 1997
    Assignee: Roussel Uclaf
    Inventors: Michel Fortin, Jean Luc Haesslein, Bertrand Heckmann
  • Patent number: 5650414
    Abstract: The bicyclic derivatives of pyridines of the formula ##STR1## and their non-toxic, pharmaceutically acceptable salts and a process and intermediates for their preparation which compounds are inhibitors of angiotensin II effects, particularly a vasoconstrictor activity.
    Type: Grant
    Filed: March 7, 1995
    Date of Patent: July 22, 1997
    Assignee: Roussel Uclaf
    Inventors: Alain Corbier, Michel Fortin, Jacques Guillaume, Jean-Luc Haesslein, Jean-Paul Vevert
  • Patent number: 5478938
    Abstract: Novel bicyclic compounds in all possible racemic, enantiomeric and diasteroisomeric forms of the formula ##STR1## having antagonistic properties for angiotensin II receptors and novel intermediates and process for their preparation.
    Type: Grant
    Filed: March 22, 1994
    Date of Patent: December 26, 1995
    Assignee: Roussel Uclaf
    Inventors: Francois Clemence, Michel Fortin, Jean-Luc Haesslein
  • Patent number: 5424314
    Abstract: A compound in all racemic or optionally active forms selected from the group consisting of a compound of the formula ##STR1## where the substituents are defined as in the specification and their non-toxic, pharmaceutically acceptable acid addition salts having anti-anoxic activity and a novel process and intermediates for their preparation.
    Type: Grant
    Filed: March 7, 1994
    Date of Patent: June 13, 1995
    Assignee: Roussel-Uclaf
    Inventors: Francois Clemence, Jean-Luc Haesslein, Claude Oberlander
  • Patent number: 5420138
    Abstract: The bicyclic derivatives of pyridines of the formula ##STR1## and their non-toxic, pharmaceutically acceptable salts and a process and intermediates for their preparation which compounds are inhibitors of angiotensin II effects, particularly a vasoconstrictor activity.
    Type: Grant
    Filed: January 29, 1993
    Date of Patent: May 30, 1995
    Assignee: Roussel-UCLAF
    Inventors: Alain Corbier, Michel Fortin, Jacques Guillaume, Jean-Luc Haesslein, Jean-Paul Vevert
  • Patent number: 5324839
    Abstract: Novel bicyclic compounds in all possible racemic, enantiomeric and diasteroisomeric forms of the formula ##STR1## having antagonistic properties for angiotensin II receptors and novel intermediates and process for their preparation.
    Type: Grant
    Filed: February 6, 1992
    Date of Patent: June 28, 1994
    Assignee: Roussel-Uclaf
    Inventors: Francois Clemence, Michel Fortin, Jean-Luc Haesslein
  • Patent number: 4975427
    Abstract: A compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, halogen, alkyl and alkoxy of 1 to 5 carbon atoms, hydroxy, trifluoromethyl and nitro, n is 0,1 or 2 and the group: ##STR2## in all possible racemic or optically active isomer forms and their non-toxic, pharmaceutically acceptable acid addition salts having analgesic, anti-anoxic and anti-ischemic neuronal protective properties.
    Type: Grant
    Filed: September 29, 1989
    Date of Patent: December 4, 1990
    Assignee: Roussel Uclaf
    Inventors: Francois Clemence, Jean-Luc Haesslein, Claude Oberlander