Patents by Inventor Jean-Luc Hefti

Jean-Luc Hefti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11207176
    Abstract: Some embodiments of the present disclosure provide a stent-valve for transcatheter implantation to replace a cardiac valve. In some embodiments, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation. In some embodiments, the stent-valve comprises a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprising material that swells in response to contact with blood or components thereof.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: December 28, 2021
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Stephane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi
  • Publication number: 20210322159
    Abstract: Some embodiments of the present disclosure provide a stent-valve for transcatheter implantation to replace a cardiac valve. In some embodiments, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation. In some embodiments, the stent-valve comprises a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprising material that swells in response to contact with blood or components thereof.
    Type: Application
    Filed: May 18, 2021
    Publication date: October 21, 2021
    Applicant: BOSTON SCIENTIFIC LIMITED
    Inventors: Stephane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi
  • Publication number: 20210154006
    Abstract: Embodiments herein relate to polymer coated prosthetic heart valves. In an embodiment, a method of manufacturing a heart valve is included, the method obtaining a frame, attaching a porous web to the frame, applying a coating over at least a portion of the porous web. In an embodiment a heart valve is included. The heart valve including a frame and a plurality of valve leaflets attached to the frame. Each valve leaflet can have a first polymer forming a porous support web and a second polymer forming a coating occluding pores in the porous support web. The valve leaflets can be attached to the frame with a connection structure that is at least partially covered by the coating. Other embodiments are also included herein.
    Type: Application
    Filed: November 10, 2020
    Publication date: May 27, 2021
    Inventors: Arnaud Humair, Jean-Luc Hefti
  • Publication number: 20210068949
    Abstract: A device for heart valve replacement comprises a valve component having at least two valve leaflets preferably made of pericardium tissue. Each valve leaflet includes at least two tabs. The device further includes a stent component configured to be radially compressible into a compressed state and expandable into a functional state. The stent component comprises a first end, a second end and at least one intermediate section arranged between said first and said second end. The intermediate section has at least two commissural posts generally aligned parallel to an axis spanning from the first end to the second end. The commissural posts are formed in the shape of a wishbone.
    Type: Application
    Filed: November 17, 2020
    Publication date: March 11, 2021
    Applicant: Symetis SA
    Inventors: Youssef Biadillah, Stephane Delaloye, Fabien Lombardi, Jean-Luc Hefti
  • Patent number: 10898321
    Abstract: A stent-valve for transcatheter implantation to replace a cardiac valve, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation, the stent-valve comprising a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprises material that swells in response to contact with blood. In some embodiments, the seal comprises a flap or pocket that is distensible in response to backpressure and/or paravalve back-flow of blood.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: January 26, 2021
    Assignee: Symetis SA
    Inventors: Stephane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi
  • Patent number: 10869760
    Abstract: A device for heart valve replacement comprises a valve component having at least two valve leaflets preferably made of pericardium tissue. Each valve leaflet includes at least two tabs. The device further includes a stent component configured to be radially compressible into a compressed state and expandable into a functional state. The stent component comprises a first end, a second end and at least one intermediate section arranged between said first and said second end. The intermediate section has at least two commissural posts generally aligned parallel to an axis spanning from the first end to the second end. The commissural posts are formed in the shape of a wishbone.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: December 22, 2020
    Assignee: Symetis SA
    Inventors: Youssef Biadillah, Stephane Delaloye, Fabien Lombardi, Jean-Luc Hefti
  • Publication number: 20200390550
    Abstract: A delivery catheter for a stent. The delivery catheter may comprise a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further comprises a handle at its proximal end and at least one sheath which may at least partially circumferentially cover said stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on said handle portion. The catheter further comprises at least one radio-opaque indicator for indicating a rotational orientation of the delivery catheter and/or the stent when observed using medical imaging during implantation of the stent.
    Type: Application
    Filed: June 16, 2020
    Publication date: December 17, 2020
    Inventors: Stephane Delaloye, Jean-Luc Hefti, Fabien Lombardi, Pierre Simonin
  • Publication number: 20200306036
    Abstract: Embodiments of the present disclosure are directed to stents, valved-stents, (e.g., single-stent-valves and double stent/valved-stent systems) and associated methods and systems for their delivery via minimally-invasive surgery. The stent component comprises a first stent section (102) a second stent section (104) a third stent section (106) and a fourth stent section (108).
    Type: Application
    Filed: June 15, 2020
    Publication date: October 1, 2020
    Applicant: Symetis SA
    Inventors: Jacques Essinger, Serge Delaloye, Jean-Luc Hefti, Stephane Delaloye
  • Patent number: 10716662
    Abstract: A stent-valve having a valve component and a stent component for housing the valve component, as well as associated methods and systems for delivery of the stent-valve via minimally-invasive surgery. The stent-valve can be configurable between two or more configurations to assist in delivery of the stent-valve to an implantation site of a patient.
    Type: Grant
    Filed: April 12, 2013
    Date of Patent: July 21, 2020
    Assignee: Boston Scientific Limited
    Inventors: Stephane Delaloye, Jean-Luc Hefti, Serge Delaloye
  • Patent number: 10709557
    Abstract: Embodiments of the present disclosure are directed to stents, valved-stents, (e.g., single-stent-valves and double stent/valved-stent systems) and associated methods and systems for their delivery via minimally-invasive surgery. The stent component comprises a first stent section (102) a second stent section (104) a third stent section (106) and a fourth stent section (108).
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: July 14, 2020
    Assignee: Symetis SA
    Inventors: Jacques Essinger, Serge Delaloye, Jean-Luc Hefti, Stephane Delaloye
  • Patent number: 10709559
    Abstract: A delivery catheter for a stent. The delivery catheter may have a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further includes a handle at its proximal end and at least one sheath which may at least partially circumferentially cover the stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on the handle portion. The catheter further includes at least one radio-opaque indicator for indicating a rotational orientation of the delivery catheter and/or the stent when observed using medical imaging during implantation of the stent.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: July 14, 2020
    Assignee: BOSTON SCIENTIFIC LIMITED
    Inventors: Stephane Delaloye, Jean-Luc Hefti, Fabien Lombardi, Pierre Simonin
  • Publication number: 20200205971
    Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a first compressor stage (100) including a hollow channel (42) with a tapered interior surface configured for compressing a stent-valve in response to longitudinal advancement of the stent-valve within the channel; and a second compressor stage (102) comprising a crimper for compressing a portion of the stent-valve without longitudinal advancement.
    Type: Application
    Filed: February 26, 2020
    Publication date: July 2, 2020
    Applicant: Symetis SA
    Inventors: Luc Mantanus, Fabien Lombardi, Pierre Simonin, Youssef Biadillah, Jean-Luc Hefti, Stephane Delaloye
  • Patent number: 10695175
    Abstract: A guide catheter is described for introduction into a patient's vasculature, to provide a substantially continuous guide lumen within the vasculature to the ascending aorta, through which one or more other functional catheters may be introduced and removed during the procedure. The guide catheter includes an aligner at its distal region for aligning the position and/or inclination of the distal region of the guide catheter with respect to the ascending aorta. The aligner includes an embolic protection filter. The guide catheter is made of material collapsible/distensible in cross section to adopt a small shape when no catheter is present inside, and to distend to a large shape to accommodate passage of functional catheter therethrough. The cross-section shape collapses/distends by folding/unfolding of material without elastic stretching of the material.
    Type: Grant
    Filed: March 17, 2016
    Date of Patent: June 30, 2020
    Assignee: Boston Scientific Limited
    Inventors: Stephane Delaloye, Jean-Luc Hefti, Youssef Biadillah
  • Patent number: 10682228
    Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a first compressor stage (100) including a hollow channel (42) with a tapered interior surface configured for compressing a stent-valve in response to longitudinal advancement of the stent-valve within the channel; and a second compressor stage (102) comprising a crimper for compressing a portion of the stent-valve without longitudinal advancement.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: June 16, 2020
    Assignee: Symetis SA
    Inventors: Luc Mantanus, Fabien Lombardi, Pierre Simonin, Youssef Biadillah, Jean-Luc Hefti, Stephane Delaloye
  • Publication number: 20200129293
    Abstract: A delivery catheter for a stent. The delivery catheter may comprise a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further comprises a handle at its proximal end and at least one sheath which may at least partially circumferentially cover said stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on said handle portion.
    Type: Application
    Filed: October 31, 2019
    Publication date: April 30, 2020
    Applicant: Symetis SA
    Inventors: JACQUES ESSINGER, STEPHANE DELALOYE, JEAN-LUC HEFTI, LUC MANTANUS
  • Publication number: 20200069422
    Abstract: Embodiments of the present disclosure are directed to stents, valved-stents, and associated methods and systems for their delivery via minimally-invasive surgery.
    Type: Application
    Filed: July 2, 2019
    Publication date: March 5, 2020
    Applicant: Symetis SA
    Inventors: JACQUES ESSINGER, STEPHANE DELALOYE, JEAN-LUC HEFTI, YOUSSEF BIADILLAH, LUC MANTANUS, IKER MALLABIABARRENA, REYNALD PASSERINI, MICHAEL PARIS, FABIEN LOMBARDI
  • Publication number: 20200060823
    Abstract: A delivery catheter for a stent. The delivery catheter may comprise a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further comprises a handle at its proximal end and at least one sheath which may at least partially circumferentially cover said stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on said handle portion.
    Type: Application
    Filed: October 31, 2019
    Publication date: February 27, 2020
    Applicant: Symetis SA
    Inventors: JACQUES ESSINGER, STEPHANE DELALOYE, JEAN-LUC HEFTI, LUC MANTANUS
  • Patent number: 10531953
    Abstract: A delivery apparatus for delivering a stent-valve for implantation within the body, the delivery apparatus configured for introduction into the body through an arterial introducer of a type having a stem insertable into the body and a mouth section that remains outside the body, the mouth section including a haemostasis valve, and wherein the delivery apparatus comprises: a first constraining sheath at a stent-valve accommodation region of the apparatus at a distal end of the apparatus, and configured for constraining at least a portion of a stent-valve at the accommodation region in a radially collapsed configuration; a delivery introducer captive on the delivery apparatus, and slidable between a first position surrounding at least a portion of the stent-valve accommodation region, and a second position in which the delivery introducer slides proximally of the stent-valve accommodation region; wherein the delivery introducer is insertable at least partly into the mouth of a said arterial introducer, the deli
    Type: Grant
    Filed: October 28, 2014
    Date of Patent: January 14, 2020
    Assignee: SYMETIS SA
    Inventors: Fabien Lombardi, Jacques Essinger, St├ęphane Delaloye, Jean-Luc Hefti, Luc Mantanus, Youssef Biadillah, Pierre Simonin
  • Publication number: 20190336278
    Abstract: Embodiments of the present disclosure are directed to stents, valved-stents, and associated methods and systems for their delivery via minimally-invasive surgery.
    Type: Application
    Filed: July 15, 2019
    Publication date: November 7, 2019
    Applicant: Symetis SA
    Inventors: JACQUES ESSINGER, YOUSSEF BIADILLAH, STEPHANE DELALOYE, JEAN-LUC HEFTI, LUC MANTANUS, REYNALD PASSERINI
  • Publication number: 20190328514
    Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a hollow channel (42) having an interior surface (50) shaped for progressively compressing the stent-valve in response to longitudinal advancement of the stent-valve within the channel; a driver (46) threadedly engaged on the exterior of the channel for generating a longitudinal driving force in response to rotation; a mover (44) having limbs (56) that project through slots (58) in the channel wall to transmit the driving force to the stent-valve within the channel; and a channel extension (48) removably attachable at the exit (54) to provide a generally cylindrical containment bore (66).
    Type: Application
    Filed: June 18, 2019
    Publication date: October 31, 2019
    Applicant: Symetis SA
    Inventors: Jacques Essinger, Stephane Delaloye, Jean-Luc Hefti, Luc Mantanus, Michael Paris