Patents by Inventor Jean-Marc MALINGE

Jean-Marc MALINGE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vitro production of DNA minicircles comprising less than 250 base pairs
    Patent number: 9701956
    Abstract: A method for the in vitro production of DNA minicircles includes steps of: a) providing nicked double-stranded oligodeoxynucleotides bunt-ended substrates having at least one phosphorylated 5? end, b) performing a ligase-mediated circularization on a reaction mixture including the nicked double-stranded oligodeoxynucleotides substrates and a DNA bending protein, and c) obtaining DNA minicircles.
    Type: Grant
    Filed: November 20, 2013
    Date of Patent: July 11, 2017
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jean-Marc Malinge, Patrick Midoux, Thomas Thibault, Chantal Pichon
  • IN VITRO PRODUCTION OF DNA MINICIRCLES COMPRISING LESS THAN 250 BASE PAIRS
    Publication number: 20150299692
    Abstract: A method for the in vitro production of DNA minicircles includes steps of: a) providing nicked double-stranded oligodeoxynucleotides bunt-ended substrates having at least one phosphorylated 5? end, b) performing a ligase-mediated circularization on a reaction mixture including the nicked double-stranded oligodeoxynucleotides substrates and a DNA bending protein, and c) obtaining DNA minicircles.
    Type: Application
    Filed: November 20, 2013
    Publication date: October 22, 2015
    Inventors: Jean-Marc MALINGE, Patrick MIDOUX, Thomas THIBAULT, Chantal PICHON