Patents by Inventor Jean Marie Mathys

Jean Marie Mathys has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of nucleic acids in cells by strand displacement amplification
    Patent number: 5523204
    Abstract: Strand Displacement Amplification for amplification of nucleic acid target sequences in situ in cells in suspension, on slides or in tissues. Excellent specimen morphology is preserved, and either DNA targets, or RNA targets, or both may be selectively amplified. In situ amplification by SDA is compatible with immunochemical techniques, so that both amplification of target sequences and immunological staining can be performed on the same specimen.
    Type: Grant
    Filed: December 10, 1993
    Date of Patent: June 4, 1996
    Assignees: Becton Dickinson and Company, University of Massachusetts
    Inventors: Robert H. Singer, Jean Marie Mathys, Kenton L. Lohman