Patents by Inventor Jean Mark Gnoth

Jean Mark Gnoth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-CARBOXYALKYL-AURISTATIN AND USE THEREOF
    Publication number: 20150148298
    Abstract: The present application relates to new derivatives of monomethylauristatin F, substituted on the N terminus by a carboxyalkyl group, processes for preparing these derivatives, their use for the treatment and/or prevention of diseases and to produce medication for the treatment and/or prevention of diseases, particularly hyperproliferative and/or angiogenic disorders such as cancer disorders, for example. Such treatments can occur as monotherapies or in combination with other medication or further therapeutic measures.
    Type: Application
    Filed: February 5, 2015
    Publication date: May 28, 2015
    Applicant: SEATTLE GENETICS, INC.
    Inventors: Hans-Georg LERCHEN, Sherif El Sheikh, Beatrix Stelet-Ludwig, Sven Golfier, Joachim Schuhmacher, Jean Mark Gnoth, Ursula Krenz
  • N-carboxyalkyl-auristatin and the use thereof
    Patent number: 8987209
    Abstract: The present application relates to new derivatives of monomethylauristatin F, substituted on the N terminus by a carboxyalkyl group, processes for preparing these derivatives, their use for the treatment and/or prevention of diseases and to produce medication for the treatment and/or prevention of diseases, particularly hyperproliferative and/or angiogenic disorders such as cancer disorders, for example. Such treatments can occur as monotherapies or in combination with other medication or further therapeutic measures.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: March 24, 2015
    Assignee: Seattle Genetics, Inc.
    Inventors: Hans-Georg Lerchen, Sherif El Sheikh, Beatrix Stelte-Ludwig, Sven Golfier, Joachim Schuhmacher, Jean Mark Gnoth, Ursula Krenz
  • Heteroaryloxy-substituted phenylaminopyrimidines as rho-kinase inhibitors
    Patent number: 7737153
    Abstract: The invention relates to heteroaryloxy-substituted phenylaminopyrimidines, to methods for the production thereof, and to the use of the same for producing medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular diseases. The inventive compounds inhibit Rho-Kinase.
    Type: Grant
    Filed: October 16, 2003
    Date of Patent: June 15, 2010
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Achim Feurer, Samir Bennabi, Heike Heckroth, Hartmut Schirok, Joachim Mittendorf, Raimund Kast, Johannes-Peter Stasch, Jean Mark Gnoth, Klaus Münter, Dieter Lang, Santiago Figueroa Perez, Heimo Ehmke