Patents by Inventor Jean-Michael Bouler

Jean-Michael Bouler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macroporous, resorbable and injectible calcium phosphate-based cements (MCPC) for bone repair, augmentation, regeneration, and osteoporosis treatment
    Patent number: 7351280
    Abstract: A composition and method for producing interconnective macroporous, resorbable and injectable calcium phosphate-based cements (MICPCs). The composition of the invention sets to poorly crystalline apatitic calcium phosphate after mixing a powder component and an aqueous solution. The multiphasic calcium phosphate components in the cement resorb at different rates allowing the timely replacement by new bone. The interconnected macroporosity in the cement allows for vascularization, entrapment of growth factors, cell colonization and tissue ingrowth. This MICPC can be used for dental and medical applications relating to bone repair, augmentation, reconstruction, regeneration, and osteoporosis treatment, and also for drug delivery, and as scaffolds for tissue engineering.
    Type: Grant
    Filed: February 9, 2005
    Date of Patent: April 1, 2008
    Assignees: New York University, Institut National Dela Sante ET Dela Recherche Medicale, The University of Nantes
    Inventors: Ibrahim Khairoun, Racquel Z. LeGeros, Guy Daculsi, Jean-Michael Bouler, Jérôme Guicheux, Olivier Gauthier
  • Macroporous, resorbable and injectible calcium phosphate-based cements (MCPC) for bone repair, augmentation, regeneration, and osteoporosis treatment
    Publication number: 20050199156
    Abstract: A composition and method for producing interconnective macroporous, resorbable and injectable calcium phosphate-based cements (MICPCs). The composition of the invention sets to poorly crystalline apatitic calcium phosphate after mixing a powder component and an aqueous solution. The multiphasic calcium phosphate components in the cement resorb at different rates allowing the timely replacement by new bone. The interconnected macroporosity in the cement allows for vascularization, entrapment of growth factors, cell colonization and tissue ingrowth. This MICPC can be used for dental and medical applications relating to bone repair, augmentation, reconstruction, regeneration, and osteoporosis treatment, and also for drug delivery, and as scaffolds for tissue engineering.
    Type: Application
    Filed: February 9, 2005
    Publication date: September 15, 2005
    Inventors: Ibrahim Khairoun, Racquel LeGeros, Guy Daculsi, Jean-Michael Bouler, Jerome Guicheux, Olivier Gauthier