Patents by Inventor Jean-Michel Thiberge

Jean-Michel Thiberge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions, and nucleic acid sequences encoding said polypeptides
    Patent number: 6258359
    Abstract: There is provided an immunogenic composition capable of inducing protective antibodies against Helicobacter infection characterized in that it comprises: i) at least one sub-unit of a urease structural polypeptide from Helicobacter pylori (SEQ ID NO: 22,26), or a fragment thereof, said fragment being recognized by antibodies reacting with Helicobacter felis urease (SEQ ID NO: 20-21), and/or at least one sub-unit of a urease structural polypeptide from Helicobacter felis (SEQ ID NO: 20-21), or a fragment thereof, said fragment being recognized by antibodies reacting with Helicobacter pylori urease (SEQ ID NO: 22-26); ii) and/or, a heat shock protein (Hsp), or chaperonin, from Helicobacter, or a fragment of said protein. The preparation, by recombinant means, of such immunogenic compositions is also provided.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 10, 2001
    Assignee: Institut Pasteur
    Inventors: Agnes Labigne, Sebastian Suerbaum, Richard L. Ferrero, Jean-Michel Thiberge
  • Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions, and nucleic acid sequences encoding said polypeptides
    Patent number: 6248330
    Abstract: There is provided an immunogenic composition capable of inducing protective antibodies against Helicobacter infection characterized in that it comprises: i) at least one sub-unit of a urease structural polypeptide from Helicobacter pylori, or a fragment thereof, said fragment being recognized by antibodies reacting with Helicobacter felis urease, and/or at least one sub-unit of a urease structural polypeptide from Helicobacter felis, or a fragment thereof, said fragment being recognized by antibodies reacting with Helicobacter pylori urease; ii) and/or, a heat shock protein (Hsp), or chaperonin, from Helicobacter, or a fragment of said protein. The preparation, by recombinant means, of such immunogenic compositions is also provided.
    Type: Grant
    Filed: May 2, 1995
    Date of Patent: June 19, 2001
    Assignee: Institut Pasteur
    Inventors: Agnes Labigne, Sebastien Suerbaum, Richard L. Ferrero, Jean-Michel Thiberge
  • Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions, and nucleic acid sequences encoding said polypeptides
    Patent number: 5843460
    Abstract: There is provided an immunogenic composition capable of inducing protective antibodies against Helicobacter infection characterized in that it comprises:i) at least one sub-unit of a urease structural polypeptide from Helicobacter pylori (SEQ ID NOS:22,26), or a fragment thereof, said fragment being recognized by antibodies reacting with Helicobacter felis urease (SEQ ID NOS:20-21), and/or at least one sub-unit of a urease structural polypeptide from Helicobacter felis (SEQ ID NOS:20-21), or a fragment thereof, said fragment being recognized by antibodies reacting with Helicobacter pylori urease (SEQ ID NOS:22-26);ii) and/or, a heat shock protein (Hsp), or chaperonin, from Helicobacter, or a fragment of said protein.The preparation, by recombinant means, of such immunogenic compositions is also provided.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 1, 1998
    Assignees: Institut Pasteur, Institut National de la Sante et de la Recherche Medicale
    Inventors: Agnes Labigne, Sebastin Suerbaum, Richard L. Ferrero, Jean-Michel Thiberge