Patents by Inventor Jean-Nicolas Desrosiers

Jean-Nicolas Desrosiers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS OF PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONES
    Publication number: 20220056025
    Abstract: This invention relates to novel methods to prepare substituted pyrido[2,3-d]pyrimidin-7(8H)-ones, and salts and stereoisomers thereof, as well as intermediates useful for the preparation of such compounds.
    Type: Application
    Filed: September 23, 2019
    Publication date: February 24, 2022
    Applicant: Pfizer Inc.
    Inventors: Adam Ross Brown, Jean-Nicolas Desrosiers, Shengquan Duan, Joel Michael Hawkins, Cheryl Myers Hayward, Mark Thomas Maloney, Sebastien Monfette, Hahdi Hakimioun Perfect, Daniel William Widlicka
  • Process for the manufacture of 6-alkynyl-pyridine derivatives
    Patent number: 11053237
    Abstract: The application includes a description of novel intermediates, of new manufacturing steps resulting in a novel and improved process for producing the intermediates and the final compounds, i.e., 6-alkynyl-pyridine derivatives. The intermediates of the invention are useful to produce 6-alkynyl-pyridine derivatives, which compounds are useful for the treatment of cancer.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: July 6, 2021
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Guanghua Lu, Guenther Huchler, Thomas Krueger, Michael Pangerl, Marco Santagostino, Jean-Nicolas Desrosiers
  • Chiral dihydrobenzooxaphosphole ligands and synthesis thereof
    Patent number: 10544177
    Abstract: This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: January 28, 2020
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Jean-Nicolas Desrosiers, Daniel Robert Fandrick, Nizar Haddad, Guisheng Li, Nitinchandra D. Patel, Bo Qu, Sonia Rodriguez, Chris Hugh Senanayake, Joshua Daniel Sieber, Zhulin Tan, Xiao-Jun Wang, Nathan K. Yee, Li Zhang, Yongda Zhang
  • PROCESS FOR THE MANUFACTURE OF 6-ALKYNYL-PYRIDINE DERIVATIVES
    Publication number: 20190308967
    Abstract: The application includes a description of novel intermediates, of new manufacturing steps resulting in a novel and improved process for producing the intermediates and the final compounds, i.e., 6-alkynyl-pyridine derivatives. The intermediates of the invention are useful to produce 6-alkynyl-pyridine derivatives, which compounds are useful for the treatment of cancer.
    Type: Application
    Filed: May 17, 2017
    Publication date: October 10, 2019
    Inventors: Guanghua LU, Guenther HUCHLER, Thomas KRUEGER, Michael PANGERL, Marco SANTAGOSTINO, Jean-Nicolas DESROSIERS
  • NOVEL CHIRAL DIHYDROBENZOOXAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF
    Publication number: 20190144475
    Abstract: This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.
    Type: Application
    Filed: January 10, 2019
    Publication date: May 16, 2019
    Inventors: Jean-Nicolas DESROSIERS, Daniel Robert FANDRICK, NIZAR HADDAD, Guisheng LI, Nitinchandra D. PATEL, Bo QU, Sonia RODRIGUEZ, Chris Hugh SENANAYAKE, Joshua Daniel SIEBER, Zhulin TAN, Xiao-Jun WANG, Nathan K. YEE, Li ZHANG, Yongda ZHANG
  • Chiral dihydrobenzooxaphosphole ligands and synthesis thereof
    Patent number: 10221203
    Abstract: This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: March 5, 2019
    Assignee: Boehringer Ingelheim International Gmbh
    Inventors: Jean-Nicolas Desrosiers, Daniel Robert Fandrick, Nizar Haddad, Guisheng Li, Nitinchandra D. Patel, Bo Qu, Sonia Rodriguez, Chris Hugh Senanayake, Joshua Daniel Sieber, Zhulin Tan, Xiao-Jun Wang, Nathan K. Yee, Li Zhang, Yongda Zhang
  • Chiral dihydrobenzoazaphosphole ligands and synthesis thereof
    Patent number: 10196413
    Abstract: This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: February 5, 2019
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Soumik Biswas, Jean-Nicolas Desrosiers, Kendricks Lao, Hari P. R. Mangunuru, Bo Qu, Sonia Rodriguez, Chris Hugh Senanayake, Joshua Daniel Sieber, Xiao-Jun Wang, Nathan K. Yee, Yongda Zhang
  • NOVEL CHIRAL DIHYDROBENZOOXAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF
    Publication number: 20180155375
    Abstract: This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.
    Type: Application
    Filed: December 6, 2017
    Publication date: June 7, 2018
    Inventors: Jean-Nicolas Desrosiers, Daniel Robert Fandrick, Nizar Haddad, Guisheng Li, Nitinchandra D. Patel, Bo Qu, Sonia Rodriguez, Chris Hugh Senanayake, Joshua Daniel Sieber, Zhulin Tan, Xiao-Jun Wang, Nathan K. Yee, Li Zhang, Yongda Zhang
  • NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF
    Publication number: 20180155377
    Abstract: This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.
    Type: Application
    Filed: December 5, 2017
    Publication date: June 7, 2018
    Inventors: Soumik Biswas, Jean-Nicolas Desrosiers, Kendricks Lao, Hari P.R. Mangunuru, Bo Qu, Sonia Rodriguez, Chris Hugh Senanayake, Joshua Daniel Sieber, Xiao-Jun Wang, Nathan K. Yee, Yongda Zhang
  • Process for preparing carboxylic acids
    Patent number: 9199904
    Abstract: The present invention relates to a process of making a compound of formula (XII) or (XIIA): wherein R1,R2, R4 and X are as defined herein.
    Type: Grant
    Filed: March 15, 2012
    Date of Patent: December 1, 2015
    Assignee: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Jean-Nicolas Desrosiers, Joe Ju Gao, Jason Alan Mulder, Jinhua J. Song, Xingzhong Zeng
  • HEXAHYDROINDENOPYRIDINE DERIVATIVES
    Publication number: 20150141651
    Abstract: This application relates methods of making compounds A and B: Compounds A and B are useful as intermediates for the preparation of pharmaceutically active compounds such as 11-?-hydroxysteroid hydrogenase type 1 (11-?-HSD1) inhibitors.
    Type: Application
    Filed: November 19, 2014
    Publication date: May 21, 2015
    Inventors: Jean-Nicolas DESROSIERS, Zhibin LI, Bo QU, Jolaine SAVOIE, Chris Hugh SENANAYAKE, Xudong WEI, Xingzhong ZENG
  • PROCESS FOR PREPARING CARBOXYLIC ACIDS
    Publication number: 20150038731
    Abstract: The present invention relates to a process of making a compound of formula (XII) or (XIIA): wherein R1, R2, R4 and X are as defined herein.
    Type: Application
    Filed: March 15, 2012
    Publication date: February 5, 2015
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Jean-Nicolas Desrosiers, Joe Ju Gao, Jason Alan Mulder, Jinhua J. Song, Xingzhong Zeng