Patents by Inventor Jean-Paul Fournier
Jean-Paul Fournier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 4983726Abstract: The invention relates to nitrosourea derivatives, a process for their preparation and pharmaceutical compositions containing them.The nitrosourea derivatives of the invention correspond to the following formula (I): ##STR1## in which: R can represent a hydrogen atom or an alkyl group from 1 to 30 carbon atoms, X represents a hydroxy group or an -NR.sub.1 R.sub.2 group, Y represents a hydrogen atom, a hydroxy group or an -NR'.sub.1 R'.sub.2 group, where R.sub.1 and/or R'.sub.1 each represent a hydrogen atom or a ##STR2## group, Hal being a halogen, and R.sub.2 and/or R'.sub.2 can each represent a hydrogen atom or an alkyl group comprising from 1 to 6 carbon atoms, R' and R" can represent hydrogen or OH, provided that at least X represents ##STR3## with R.sub.1 representing ##STR4## or Y represents ##STR5## with R'.sub.1 representing ##STR6## and provided that either R' represents hydrogen or R" represents hydrogen, and R' and R" cannot be simultaneously hydrogen atoms.Type: GrantFiled: November 24, 1989Date of Patent: January 8, 1991Assignee: Sanofi S.A.Inventors: Pierre Roger, Patrick Choay, Claude Monneret, Jean-Paul Fournier
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Patent number: 4980349Abstract: The invention relates to new compounds corresponding to formula I: ##STR1## in which: W represents C=O, CH.sub.2 or CHOH,Z represents ##STR2## R.sub.1 and R.sub.2 represent especially Cl or F, R, R' and R" represent especially H,X represents especially CH.sub.2,Y represents especially COOH,u and v are two integers ranging from 0 to 10,p and q take the value 0 or 1,n and m are two integers ranging 0 to 10 andt is 0 or 1the total number of carbon atoms in the chain ##STR3## ranging from 2 to 20, and to their physiologically acceptable salts obtained with organic or inorganic acids.These compounds are useful for preparing medicinal products which have, especially, anti-inflammatory properties.Type: GrantFiled: November 12, 1987Date of Patent: December 25, 1990Assignee: SANOFIInventors: Pierre Roger, Jean-Paul Fournier, Alain Martin, Jean Choay
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Patent number: 4902791Abstract: The invention relates to nitrosourea derivatives, a process for their preparation and pharmaceutical compositions containing them.The nitrosourea derivatives of the invention correspond to the following formula (I): ##STR1## in which: R can represent a hydrogen atom or an alkyl group from 1 to 30 carbon atoms, X represents a hydroxy group or an --NR.sub.1 R.sub.2 group, Y represents a hydrogen atom, a hydroxy group or an --NR'.sub.1 R'.sub.2 group, where R.sub.1 and/or R'.sub.1 each represent a hydrogen atom or a ##STR2## group, Hal being a halogen, and R.sub.2 and/or R'.sub.2 can each represent a hydrogen atom or an alkyl group comprising from 1 to 6 carbon atoms, R' and R" can represent hydrogen or OH, provided that at least X represents ##STR3## with R.sub.1 representing ##STR4## or Y represents ##STR5## with R'.sub.1 representing ##STR6## and provided that either R' represents hydrogen or R" represents hydrogen, and R' and R" cannot be simultaneously hydrogen atoms.Type: GrantFiled: April 14, 1988Date of Patent: February 20, 1990Assignee: Sanofi S.A.Inventors: Pierre Roger, Patrick Choay, Claude Monneret, Jean-Paul Fournier, Alain Martin
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Patent number: 4883903Abstract: The subject of the invention is a novel procedure for the preparation of the compounds of formula I: ##STR1## in which n varies in particular from 2 to 5 and R represents Cl, Br or FZ represents in particular hydrogen, characterized in that the halogenoformate of formula II: ##STR2## R and n having the meanings indicated above, Y representing a halogen, is made to react with NH.sub.2 CH.sub.2 CH.sub.2 Cl to form the compound of formula Ia: ##STR3## in which R has the meanings indicated above, and in that the compound Ia is treated directly with nitrosylsulfuric acid.Type: GrantFiled: April 22, 1988Date of Patent: November 28, 1989Assignee: SanofiInventors: Pierre Roger, Jean-Paul Fournier, Rolande Leroy
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Patent number: 4871843Abstract: The invention relates to new N-cyclic benzenesulfonamides, their process of preparation and their use as active substance of pharmaceutical compositions. The new benzenesulfonamides according to the invention correspond to the following general formula (I): ##STR1## in which: V represents, for example, hydrogen,W represents, for example CF.sub.3,X represents, for example, hydrogen,Y represents, for example, hydrogen,n is 2 or 3,Z represents, for example, the group NR.sub.4, in which R.sub.4 represents, for example, hydrogen.These compounds are useful in pharmaceutical compositions for the treatment of nervous disorders with anxiety.Type: GrantFiled: July 26, 1985Date of Patent: October 3, 1989Assignee: DROPIC-Societe Civile de gestion de droits de Propriete IndustrielleInventors: Pierre Roger, Patrick Choay, Jean-Paul Fournier
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Patent number: 4760062Abstract: The invention relates to new N-cyclic benzenesulfonamides, their process of preparation and their use as active substance of pharmaceutical compositions. The new benzenesulfonamides according to the invention correspond to the following general formula (I): ##STR1## in which: V represents, for example, hydrogen,W represents, for example CF.sub.3,X represents, for example, hydrogen,Y represents, for example, hydrogen,n is 2 or 3,Z represents, for example, the group NR.sub.4, in which R.sub.4 represents, for example, hydrogen.These compounds are useful in pharmaceutical compositions for the treatment of nervous disorders with anxiety.Type: GrantFiled: October 18, 1984Date of Patent: July 26, 1988Assignee: DROPIC, Societe Civile de gestion de droits de Propriete IndustrielleInventors: Pierre Roger, Patrick Choay, Jean-Paul Fournier
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Patent number: 4714700Abstract: The invention relates to new N-substituted benzenesulfonamides, the process for their preparation and their use.The compounds according to the invention correspond to the general formula (I): ##STR1## in which: n and m have values from 0 to 4;R.sub.3 and R.sub.4 represent in particular a lower alkyl radical;R.sub.1 and R.sub.2 represent in particular hydrogen atoms, linear or branched alkyl groups having from 1 to 4 carbon atoms;R.sub.5 represents particularly a hydrogen atom, a halogen, the NO.sub.2, NH.sub.2, or CF.sub.3 group;R.sub.6 and R.sub.7 represent in particular a hydrogen atom, an alkyl radical of 1 to 6 carbon atoms.The invention is useful in the preparation of tranquilizing or anxiolytic medicines.Type: GrantFiled: February 12, 1985Date of Patent: December 22, 1987Assignee: Choay S.A.Inventors: Jean-Paul Fournier, Patrick Choay
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Patent number: 4618459Abstract: The invention relates to trisubstituted sulfohalides, the process for their preparation and their use as intermediate products for the manufacture of novel compounds.The trisubstituted sulfohalides according to the invention correspond to the following general formula (I): ##STR1## in which: X is a halogen atom, particularly bromine or preferably chlorine;R.sub.3 and R.sub.4 each represent, independently of one another, a lower alkyl radical having from 1 to 4 carbon atoms, A represents hydrogen, halogen, alkoxy radicals having from 1 to 4 carbon atoms, alkylsulfonyl groups having from 1 to 4 carbon atoms, or the group NO.sub.2, or CF.sub.3.The invention is useful in the manufacture of medicaments.Type: GrantFiled: December 30, 1983Date of Patent: October 21, 1986Assignee: Choay S.A.Inventors: Jean-Paul Fournier, Patrick Choay
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Patent number: 4585769Abstract: The invention relates to new benzenesulfonyl-lactams, process for their preparation and their use as active substance in pharmaceutical compositions.Compounds according to the invention correspond to the general formula (I): ##STR1## in which: X can represent hydrogen,Y can represent the CF.sub.3 group,Z can represent chlorine,W can represent hydrogen,n is 1, 2 or 3,R.sub.1 can represent hydrogen,R.sub.2 can represent the OH group, provided that when n is 2 or 3, X or Z represents an alkoxy group from 1 to 4 carbon atoms or that Y represents the CF.sub.3 or NO.sub.2 group, and when n is 1, Y or W represents the CF.sub.3 group.These new compounds may be introduced as active substances, particularly in the treatment of disorders of the memory.Type: GrantFiled: October 18, 1984Date of Patent: April 29, 1986Assignee: DROPIC - Societe Civile de gestion de droits de propriete Industrielle CHOAYInventors: Pierre Roger, Patrick Choay, Jean-Paul Fournier
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Patent number: 4457875Abstract: The invention relates to trisubstituted sulfohalides, the process for their preparation and their use as intermediate products for the manufacture of novel compounds. The trisubstituted sulfohalides according to the invention correspond to the following general formula (I): ##STR1## in which: X is a halogen atom, particularly bromine or preferably chlorine;R.sub.3 and R.sub.4 each represent, independently of one another, a lower alkyl radical having from 1 to 4 carbon atoms, A represents hydrogen, halogen, alkoxy radicals having from 1 to 4 carbon atoms, alkylsulfonyl groups having from 1 to 4 carbon atoms, or the group NO.sub.2, or CF.sub.3. The invention is useful in the manufacture of medicaments.Type: GrantFiled: April 23, 1982Date of Patent: July 3, 1984Assignee: Choay S.A.Inventors: Jean-Paul Fournier, Patrick Choay
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Patent number: 4225611Abstract: Amino-4 chloro-5 methoxy-2 N-(N-ethyl methyl-2 pyrrolidino) benzenesulfonamide is a novel compound corresponding to the formula ##STR1## and is prepared by reacting sulfonyl chloride of the formula ##STR2## with the amine of the formula ##STR3## This compound and its addition salts with physiologically acceptable mineral or organic acids, is a useful medicament for the treatment of ulcerous gastro-duodenal disorders.Type: GrantFiled: April 5, 1978Date of Patent: September 30, 1980Assignee: Choay S.A.Inventors: Jean-Paul Fournier, Patrick Choay
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Patent number: 4211776Abstract: The invention relates to new N-substituted benzenesulphonamides of general formula ##STR1## in which n is 2 or 3,R.sub.1 and R.sub.2 are hydrogen atoms, methyl, ethyl groups, or jointly form with the nitrogen a nitrogenized heterocyclic ring having 5 or 6 members, in particular a piperidino, pyrrolidino or morpholino group.R.sub.3 is a hydrogen atom, an NO.sub.2 group, an NH.sub.2 group, or a halogen,R.sub.4 is a hydrogen, a halogen, NH.sub.2 group or a sulphonamide group.These compounds are useful as active substances of medicaments, in particular as antiemetic.Type: GrantFiled: October 2, 1978Date of Patent: July 8, 1980Assignee: Choay S.A.Inventors: Robert C. Moreau, Jean-Paul Fournier
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Patent number: 4132786Abstract: The invention relates to new N-substituted benzenesulphonamides of general formula ##STR1## in which N IS 2 OR 3,R.sub.1 and R.sub.2 are hydrogen atoms, methyl, ethyl groups, or jointly form with the nitrogen a nitrogenized heterocyclic ring having 5 or 6 members, in particular a piperidino, pyrrolidino or morpholino group,R.sub.3 is a hydrogen atom, an NO.sub.2 group, an NH.sub.2 group, or a halogen,R.sub.4 is a hydrogen, a halogen, an NH.sub.2 group or a sulphonamide group.These compounds are useful as active substances of medicaments, in particular as antiemetic.Type: GrantFiled: June 8, 1976Date of Patent: January 2, 1979Inventors: Robert C. Moreau, Jean-Paul Fournier