Patents by Inventor Jean-Paul Kan

Jean-Paul Kan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridazine derivatives
    Patent number: 5656631
    Abstract: The present invention relates to pyridazine derivatives of formula: ##STR1## which are useful as ligands of cholinergic receptors, in particular, receptors of the M.sub.1 type.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 12, 1997
    Assignee: Sanofi
    Inventors: Robert Boigegrain, Roger Brodin, Jean Paul Kan, Dominique Olliero, Camille Georges Wermuth, Jean-Jacques Bourguignon, Paul Worms
  • 3-(N-azabicycloalkyl)aminopyridazine derivatives and pharmaceutical compositions in which they are present
    Patent number: 5276036
    Abstract: The invention relates to 3-aminopyridazine derivatives.These compounds have the formula ##STR1## in which: R.sub.V is a linear or branched C.sub.1 -C.sub.4 alkyl group;R.sub.6 is hydrogen, a C.sub.1 -C.sub.3 alkoxy or a hydroxyl group; andZ is a group ##STR2## in which: n.sub.1 and n.sub.2 independently are zero or one,Y.sub.1 and Y.sub.2 independently are hydrogen or a C.sub.1 -C.sub.3 alkyl group, andT is a dialkylamino group in which the alkyls are C.sub.1 -C.sub.3, if Y.sub.1 or Y.sub.2 is other than hydrogen, or T is a heterocycle selected from: ##STR3## Application: drugs active on the central nervous system.
    Type: Grant
    Filed: May 15, 1992
    Date of Patent: January 4, 1994
    Assignee: Elf Sanofi
    Inventors: Jean-Jacques Bourguignon, Jean-Paul Kan, Camille G. Wermuth
  • Pyridazine derivatives having a psychotropic action, and medicaments in which they are present
    Patent number: 4631280
    Abstract: The invention relates to pyridazine derivatives substituted in the 4-position by a cyano group. It also relates to a process for the preparation of these products and their application as medicaments.
    Type: Grant
    Filed: May 20, 1985
    Date of Patent: December 23, 1986
    Assignee: Sanofi
    Inventors: Jean-Paul Kan, Kathleen Biziere, Camille-Georges Wermuth
  • 2-piperazinopyrimidine salt and pharmaceutical compositions containing it
    Patent number: 4602015
    Abstract: A salt of 2-(1-piperazinyl) pyrimidine salt with 2-naphthalene sulfonic acid, having a dopaminergic psychotropic activity and pharmaceutical compositions containing it as active principle for the treatment of behavioral problems.
    Type: Grant
    Filed: February 14, 1985
    Date of Patent: July 22, 1986
    Assignee: Sanofi
    Inventors: Emilio Crisafulli, Marco Frigerio, Jean-Paul Kan
  • Pyridazine derivatives having a psychotropic action and compositions
    Patent number: 4565814
    Abstract: This invention relates to pyridazine derivatives substituted in the 4-position by a cyano group having psychotropic activity. It also relates to a process for the preparation of these products and their application as medicaments.
    Type: Grant
    Filed: January 18, 1984
    Date of Patent: January 21, 1986
    Assignee: Sanofi
    Inventors: Jean-Paul Kan, Kathleen Biziere, Camille-Georges Wermuth
  • 1-Piperazinyl 4-phenylquinazoline compounds having antidepressant properties and drugs containing same
    Patent number: 4540696
    Abstract: The present invention relates to new derivatives of formula: ##STR1## in which: R.sub.3 denotes a halogen, preferably chlorine, or a nitro group,R.sub.4 represents hydrogen or a lower alkyl group having from 1 to 4 atoms of carbon,R.sub.5 represents an atom of halogen, preferably chlorine or fluorine.It also relates to a process for preparing products of formula (II) and to the drugs containing at least one product of formula (II).
    Type: Grant
    Filed: February 3, 1983
    Date of Patent: September 10, 1985
    Assignee: Sanofi S.A.
    Inventors: Kathleen Biziere, Andre Hallot, Jean-Paul Kan
  • Aminated derivatives of pyridazine substituted in 6 position by a heterocycle or an alicycle and compositions, said derivatives being active on the central nervous system
    Patent number: 4524070
    Abstract: The present invention relates to aminated derivatives of pyridazine of formula: ##STR1## in which: . R.sub.1 designates a 2-thienyl, 3-thienyl or cyclohexyl group;R.sub.2 represents a lower alkyl group (1 to 4 atoms of carbon), or an atom of hydrogen as well as the salts of said derivatives with the acids; which compounds effect the central nervous system and may be used in human medicine to treat depression. It also relates to a process for preparing said derivatives and the drugs containing them.
    Type: Grant
    Filed: January 18, 1984
    Date of Patent: June 18, 1985
    Assignee: Sanofi
    Inventors: Jean-Paul Kan, Kathleen Biziere, Camille-Georges Wermuth
  • Amino derivatives of pyridazine, and compositions thereof for the central nervous system
    Patent number: 4508720
    Abstract: The present invention relates to amino derivatives of pyridazine of general formula: ##STR1## in which one of the substituents R.sub.1, R.sub.2 or R.sub.3 represents a phenyl or hydroxyphenyl group, while the other two represent hydrogen or an alkyl group with C.sub.1 -C.sub.4 ;A represents a linear or branched alkylene group having 2 to 5 carbon atoms;X represents hydrogen or an alkyl group with C.sub.1 -C.sub.4, as well as the salts of said derivatives with the pharmaceutically acceptable acids, and also relates to a process for preparing the products of formula (I) and to drugs containing a product of formula (I).
    Type: Grant
    Filed: July 29, 1982
    Date of Patent: April 2, 1985
    Assignee: Sanofi
    Inventors: Jean-Paul Kan, Kathleen Biziere, Camille G. Wermuth