Abstract: Single-domain antibodies that bind the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) spike protein are disclosed. The single-domain antibodies include binding domains that bind epitopes of the Spike ectodomain inside and outside the receptor binding domain. The single-domain antibodies can be used for multiple purposes including in the research, diagnosis, and prophylactic or therapeutic treatment of COVID-19.

Abstract: The invention provides a plant cell, part, tissue culture or whole plant comprising at least one disrupted KRP gene of the present invention. The present invention also provides methods of increasing weight, size, and/or number of one or more organs, and/or yield of a plant by utilizing the disrupted KRP genes of the present invention. Furthermore, methods of breeding plants to produce new plants having increased weight, size, and/or number of one or more organs, and/or yield are provided. The present invention provides isolated Kinase inhibitor Protein (KIP) Related Protein (KRP) polynucleotide sequences and isolated KRP polypeptide sequences and methods of their use. Exemplary plants include wheat, rice and soy bean.

Abstract: The invention provides a wheat cell, part, tissue culture or whole plant comprising at least one disrupted KRP gene of the present invention. The present invention also provides methods of increasing weight, size, and/or number of one or more organs, and/or yield of a wheat plant by utilizing the disrupted KRP genes of the present invention. Furthermore, methods of breeding wheat plants to produce new wheat plants having increased weight, size, and/or number of one or more organs, and/or yield are provided. The present invention provides isolated Kinase Inhibitor Protein (KIP) Related Protein (KRP) polynucleotide sequences and isolated KRP polypeptide sequences and methods of their use.

Abstract: The present invention provides expression vectors comprising polynucleotides encoding mutant Zea mays KRP dominant negative proteins, and methods of using the same. In addition, transgenic plants expressing said KRP dominant negative proteins are provided. Furthermore, methods of increasing average seed weight, seed size, seed number and/or yield of a plant by using said KRP dominant negative proteins are provided.

Abstract: The invention provides a plant cell, part, tissue culture or whole plant comprising at least one disrupted KRP gene of the present invention. The present invention also provides methods of increasing weight, size, and/or number of one or more organs, and/or yield of a plant by utilizing the disrupted KRP genes of the present invention. Furthermore, methods of breeding plants to produce new plants having increased weight, size, and/or number of one or more organs, and/or yield are provided. The present invention provides isolated Kinase inhibitor Protein (KIP) Related Protein (KRP) polynucleotide sequences and isolated KRP polypeptide sequences and methods of their use. Exemplary plants include wheat, rice and soy bean.

Abstract: The invention provides a plant cell, part, tissue culture or whole plant comprising at least one disrupted KRP gene of the present invention. The present invention also provides methods of increasing weight, size, and/or number of one or more organs, and/or yield of a plant by utilizing the disrupted KRP genes of the present invention. Furthermore, methods of breeding plants to produce new plants having increased weight, size, and/or number of one or more organs, and/or yield are provided. The present invention provides isolated Kinase Inhibitor Protein (KIP) Related Protein (KRP) polynucleotide sequences and isolated KRP polypeptide sequences and methods of their use. Exemplary plants include wheat, rice and soybean.

Abstract: The invention provides a wheat cell, part, tissue culture or whole plant comprising at least one disrupted KRP gene of the present invention. The present invention also provides methods of increasing weight, size, and/or number of one or more organs, and/or yield of a wheat plant by utilizing the disrupted KRP genes of the present invention. Furthermore, methods of breeding wheat plants to produce new wheat plants having increased weight, size, and/or number of one or more organs, and/or yield are provided. The present invention provides isolated Kinase Inhibitor Protein (KIP) Related Protein (KRP) polynucleotide sequences and isolated KRP polypeptide sequences and methods of their use.

Abstract: The invention provides a wheat cell, part, tissue culture or whole plant comprising at least one disrupted KRP gene of the present invention. The present invention also provides methods of increasing weight, size, and/or number of one or more organs, and/or yield of a wheat plant by utilizing the disrupted KRP genes of the present invention. Furthermore, methods of breeding wheat plants to produce new wheat plants having increased weight, size, and/or number of one or more organs, and/or yield are provided. The present invention provides isolated Kinase Inhibitor Protein (KIP) Related Protein (KRP) polynucleotide sequences and isolated KRP polypeptide sequences and methods of their use.

Abstract: The invention provides early embryo and early endosperm specific or preferred promoters, which are capable of driving and/or regulating the expression of an operably linked nucleic acid in a maize plant during early development of embryo and/or endosperm, and methods of isolating them. The promoters are derived from Zea mays or other plant species. The invention also provides compositions comprising one or more said promoters and methods of using the same.

Abstract: The invention provides a plant cell, part, tissue culture or whole plant comprising at least one disrupted KRP gene of the present invention. The present invention also provides methods of increasing weight, size, and/or number of one or more organs, and/or yield of a plant by utilizing the disrupted KRP genes of the present invention. Furthermore, methods of breeding plants to produce new plants having increased weight, size, and/or number of one or more organs, and/or yield are provided. The present invention provides isolated Kinase Inhibitor Protein (KIP) Related Protein (KRP) polynucleotide sequences and isolated KRP polypeptide sequences and methods of their use. Exemplary plants include wheat, rice and soybean.

Abstract: The invention provides a wheat cell, part, tissue culture or whole plant comprising at least one disrupted KRP gene of the present invention. The present invention also provides methods of increasing weight, size, and/or number of one or more organs, and/or yield of a wheat plant by utilizing the disrupted KRP genes of the present invention. Furthermore, methods of breeding wheat plants to produce new wheat plants having increased weight, size, and/or number of one or more organs, and/or yield are provided. The present invention provides isolated Kinase Inhibitor Protein (KIP) Related Protein (KRP) polynucleotide sequences and isolated KRP polypeptide sequences and methods of their use.

Abstract: The present invention provides expression vectors comprising polynucleotides encoding mutant Zea mays KRP dominant negative proteins, and methods of using the same. In addition, transgenic plants expressing said KRP dominant negative proteins are provided. Furthermore, methods of increasing average seed weight, seed size, seed number and/or yield of a plant by using said KRP dominant negative proteins are provided.