Patents by Inventor Jean-Paul PFEFEN

Jean-Paul PFEFEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEW TREATMENT OF SMA
    Publication number: 20230338382
    Abstract: The present invention relates to 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one for use in the treatment of spinal muscular atrophy (SMA), its pharmaceutical composition to be used in the treatment of SMA, its methods of treatment thereof.
    Type: Application
    Filed: December 5, 2022
    Publication date: October 26, 2023
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Jean-Paul Pfefen, Heidemarie Kletzl, Lutz Mueller
  • Treatment of SMA
    Patent number: 11534444
    Abstract: The present invention relates to 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one for use in the treatment of spinal muscular atrophy (SMA), its pharmaceutical composition to be used in the treatment of SMA, its methods of treatment thereof.
    Type: Grant
    Filed: April 2, 2020
    Date of Patent: December 27, 2022
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jean-Paul Pfefen, Heidemarie Kletzl, Lutz Mueller
  • METHOD FOR TREATING MULTIPLE SCLEROSIS
    Publication number: 20210388099
    Abstract: The present invention concerns methods for treating multiple sclerosis (MS) in a patient, and an article of manufac-ture with instructions for such use.
    Type: Application
    Filed: March 16, 2021
    Publication date: December 16, 2021
    Inventors: David LEPPERT, Anne-Marie LI-KWAI-CHEUNG, Michele LIBONATI, Donna MASTERMAN, Jean-Paul PFEFEN, Craig SMITH, Algirdas Jonas Kakarieka WEISSKOPF, Jiameng ZHANG, Peter S. CHIN, Hideki GARREN
  • NEW TREATMENT OF SMA
    Publication number: 20200375993
    Abstract: The present invention relates to 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one for use in the treatment of spinal muscular atrophy (SMA), its pharmaceutical composition to be used in the treatment of SMA, its methods of treatment thereof.
    Type: Application
    Filed: April 2, 2020
    Publication date: December 3, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jean-Paul Pfefen, Heidemarie Kletzl, Lutz Mueller
  • METHOD FOR TREATING MULTIPLE SCLEROSIS
    Publication number: 20180327505
    Abstract: The present invention concerns methods for treating multiple sclerosis (MS) in a patient, and an article of manufacture with instructions for such use.
    Type: Application
    Filed: April 5, 2018
    Publication date: November 15, 2018
    Inventors: David LEPPERT, Anne-Marie LI-KWAI-CHEUNG, Michele LIBONATI, Donna MASTERMAN, Jean-Paul PFEFEN, Craig SMITH, Algirdas Jonas Kakarieka WEISSKOPF, Jiameng ZHANG, Peter S. CHIN, Hideki GARREN