Patents by Inventor Jean Philippe Nougayrede

Jean Philippe Nougayrede has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED ESCHERICHIA COLI STRAIN NISSLE AND TREATMENT OF GASTROINTESTINAL DISORDER
    Publication number: 20220265731
    Abstract: The invention relates to the field of modified Escherichia coli strain Nissle 1917 (EcN) and its use for treating gastro-in-testinal disorders. The invention is based on the study of the mechanisms implicated in the probiotic properties of the Escherichia coli strain Nissle 1917 (EcN). This study has allowed the inventors to decouple the probiotic activity of EcN from its genotoxic activity by demonstrating that EcN ClbP protein, the enzyme that activates the genotoxin colibactin, is also required for the siderophore-microcins activity of probiotic EcN, but interestingly, not its enzymatic domain that cleaves precolibactin to form active colibactin.
    Type: Application
    Filed: July 7, 2020
    Publication date: August 25, 2022
    Inventors: Eric Oswald, Jean-Philippe Nougayrede, Clémence Massip, Patricia Martin, Priscilla Branchu
  • Use of cells containing a specific DNA molecule as cytopathic agents to inhibit the proliferation of cells
    Patent number: 8277798
    Abstract: The present invention relates to the use of cells containing in their genome a specific DNA molecule, as cytopathic agents able to inhibit the proliferation of cells, when these proliferative cells are contacted with the cells containing the above-mentioned DNA molecule.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: October 2, 2012
    Assignees: Institut National de la Recherche Agronomique, Bayerische Julius-Maximilians-Universitat Wurzburg
    Inventors: Eric Oswald, Jörg Hacker, Jean Philippe Nougayrede, Ulrich Dobrindt, Frédéric Taieb, Fabrice Pierre
  • USE OF CELLS CONTAINING A SPECIFIC DNA MOLECULE AS CYTOPATHIC AGENTS TO INHIBIT THE PROLIFERATION OF CELLS
    Publication number: 20090238804
    Abstract: The present invention relates to the use of cells containing in their genome a specific DNA molecule, as cytopathic agents able to inhibit the proliferation of cells, when these proliferative cells are contacted with the cells containing the above-mentioned DNA molecule.
    Type: Application
    Filed: May 10, 2007
    Publication date: September 24, 2009
    Applicant: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE
    Inventors: Eric Oswald, Jörg Hacker, Jean Philippe Nougayrede, Ulrich Dobrindt, Frederic Taieb, Fabrice Pierre