Patents by Inventor Jean Philippe Stephan

Jean Philippe Stephan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING CANCER AND PREVENTING CANCER DRUG RESISTANCE
    Publication number: 20170209444
    Abstract: Provided herein are methods of using antagonists of G9a, for example, for treating cancer and/or preventing drug resistance in an individual. For example, a method of treating cancer in an individual comprising administering to the individual an antagonist of G9a alone or in combination with a cancer therapy agent is provided. In some embodiments, the antagonist of G9a increases the period of cancer sensitivity and/or delays development of cancer resistance.
    Type: Application
    Filed: June 23, 2015
    Publication date: July 27, 2017
    Applicant: Genentech Inc.
    Inventors: Marie Classon, Gulfem Dilek Guler, Robert Pitti, Jean-Philippe Stephan, Charles Albert Tindell
  • METHODS OF TREATING CANCER AND PREVENTING CANCER DRUG RESISTANCE
    Publication number: 20160160213
    Abstract: Provided herein are methods of treating and/or preventing cancer drug resistance using modulators of chromatin modifiers (e.g., antagonists of chromatin modifiers) described herein.
    Type: Application
    Filed: September 14, 2015
    Publication date: June 9, 2016
    Applicant: GENENTECH, INC.
    Inventors: Marie Classon, Jean-Philippe Stephan
  • METHODS OF TREATING CANCER AND PREVENTING CANCER DRUG RESISTANCE
    Publication number: 20160143910
    Abstract: Provided herein are methods of treating and/or preventing cancer drug resistance using antagonists of KDM5.
    Type: Application
    Filed: March 14, 2014
    Publication date: May 26, 2016
    Applicants: CONSTELLATION PHARMACEUTICALS, INC., GENENTECH, INC.
    Inventors: Shilpi Arora, Michael Robert Costa, Ted Lau, Patrick Trojer, Brian K. Albrecht, Shane Buker, Marie Classon, Victor S. Gehling, Jean-Christophe Harmange, Erica L. Jackson, Jun Liang, Heidi Phillips, Peter Sandy, Jeffrey Settleman, Jean-Philippe Stephan
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20090148878
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: March 18, 2008
    Publication date: June 11, 2009
    Inventors: Kevin P. Baker, Dan L. Eaton, Ellen Filvaroff, Audrey Goddard, J. Christopher Grimaldi, Austin L. Gurney, Victoria Smith, Jean Philippe Stephan, Colin K. Watanabe, William I. Wood, Zemin Zhang, Sherman Fong
  • PRO6308 polypeptide
    Patent number: 7491797
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: February 17, 2009
    Assignee: Genentech, Inc.
    Inventors: Kevin P. Baker, Dan L. Eaton, Ellen Filvaroff, Audrey Goddard, J. Christopher Grimaldi, Austin L. Gurney, Victoria Smith, Jean Philippe Stephan, Colin K. Watanabe, William I. Wood, Zemin Zhang, Sherman Fong
  • Anti-PRO7168 antibodies
    Patent number: 7452975
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: November 18, 2008
    Assignee: Genentech, Inc.
    Inventors: Kevin P. Baker, Dan L. Eaton, Ellen Filvaroff, Audrey Goddard, J. Christopher Grimaldi, Austin L. Gurney, Victoria Smith, Jean Philippe Stephan, Colin K. Watanabe, William I. Wood, Zemin Zhang, Sherman Fong
  • Anti-PRO4980 antibodies
    Patent number: 7312303
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: December 25, 2007
    Assignee: Genentech, Inc.
    Inventors: Kevin P. Baker, Dan L. Eaton, Ellen Filvaroff, Audrey Goddard, J. Christopher Grimaldi, Austin L. Gurney, Victoria Smith, Jean Philippe Stephan, Colin K. Watanabe, William I. Wood, Zemin Zhang, Sherman Fong
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Patent number: 7304126
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: December 4, 2007
    Assignee: Genentech, Inc.
    Inventors: Kevin P. Baker, Dan L. Eaton, Ellen Filvaroff, Audrey Goddard, J. Christopher Grimaldi, Austin L. Gurney, Victoria Smith, Jean Philippe Stephan, Colin K. Watanabe, William I. Wood, Zemin Zhang, Sherman Fong
  • PRO698 polypeptides
    Patent number: 7297769
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: September 9, 2002
    Date of Patent: November 20, 2007
    Assignee: Genentech, Inc.
    Inventors: Kevin P. Baker, Dan L. Eaton, Ellen Filvaroff, Audrey Goddard, J. Christopher Grimaldi, Austin L. Gurney, Victoria Smith, Jean Philippe Stephan, Colin K. Watanabe, William I. Wood, Zemin Zhang, Sherman Fong
  • PRO6496 polypeptides
    Patent number: 7297770
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods, for producing the polypeptides of the present invention.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: November 20, 2007
    Assignee: Genentech, Inc.
    Inventors: Kevin P. Baker, Dan L. Eaton, Ellen Filvaroff, Audrey Goddard, J. Christopher Grimaldi, Austin L. Gurney, Victoria Smith, Jean Philippe Stephan, Colin K. Watanabe, William I. Wood, Zemin Zhang, Sherman Fong
  • PRO7168 polypeptides
    Patent number: 7294696
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: November 13, 2007
    Assignee: Genentech Inc.
    Inventors: Kevin P. Baker, Dan L. Eaton, Ellen Filvaroff, Audrey Goddard, J. Christopher Grimaldi, Austin L. Gurney, Victoria Smith, Jean Philippe Stephan, Colin K. Watanabe, William I. Wood, Zemin Zhang, Sherman Fong
  • PRO10268 polypeptides
    Patent number: 7294695
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: November 13, 2007
    Assignee: Genentech, Inc.
    Inventors: Kevin P. Baker, Dan L. Eaton, Ellen Filvaroff, Audrey Goddard, J. Christopher Grimaldi, Austin L. Gurney, Victoria Smith, Jean Philippe Stephan, Colin K. Watanabe, William I. Wood, Zemin Zhang, Sherman Fong
  • PRO9925 POLYPEPTIDES
    Publication number: 20070238859
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: August 13, 2002
    Publication date: October 11, 2007
    Inventors: Kevin Baker, Luc Desnoyers, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Victoria Smith, Jean-Philippe Stephan, Colin Watanabe, William Wood
  • SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME
    Publication number: 20070207147
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: October 24, 2006
    Publication date: September 6, 2007
    Applicant: Genentech, Inc.
    Inventors: Kevin Baker, Luc Desnoyers, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Victoria Smith, Jean-Philippe Stephan, Colin Watanabe, William Wood
  • PRO1313 polypeptides
    Patent number: 7238790
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: September 11, 2002
    Date of Patent: July 3, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, Austin L. Gurney, Jean Philippe Stephan, William I. Wood
  • Anti-PRO 1313 antibodies
    Patent number: 7235642
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: September 11, 2002
    Date of Patent: June 26, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, Austin L. Gurney, Jean Philippe Stephan, William I. Wood
  • Non-human transgenic animal models for hepatocellular carcinoma
    Publication number: 20070143871
    Abstract: The invention relates to the field of non-human, transgenic animal models for hepatocellular carcinoma.
    Type: Application
    Filed: November 6, 2006
    Publication date: June 21, 2007
    Applicant: Genentech, Inc.
    Inventors: Dorothy French, Avi Ashkenazi, Jean-Philippe Stephan, Luc Desnoyers
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060074220
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: August 12, 2002
    Publication date: April 6, 2006
    Inventors: Kevin Baker, Luc Desnoyers, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Victoria Smith, Jean-Philippe Stephan, Colin Watanabe, William Wood
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060074033
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 12, 2002
    Publication date: April 6, 2006
    Inventors: Kevin Baker, Dan Eaton, Ellen Filvaroff, Audrey Goddard, J. Grimaldi, Austin Gurney, Victoria Smith, Jean-Philippe Stephan, Colin Watanabe, William Wood, Zemin Zhang, Sherman Fong
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20060074224
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: August 12, 2002
    Publication date: April 6, 2006
    Inventors: Kevin Baker, Luc Desnoyers, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Victoria Smith, Jean-Philippe Stephan, Colin Watanabe, William Wood