Patents by Inventor Jean-Pierre Caruelle

Jean-Pierre Caruelle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8883715
    Abstract: A process for treating fibroses including administering a therapeutically effective amount of a pharmaceutical composition which includes at least one biocompatible polymer of the following general formula (I): AaXxYy wherein: A represents a monomer selected from the group consisting of a sugar or —(O—CH2—CH2—CO)—, X represents a carboxyl group bonded to monomer A, Y represents a sulfate or sulfonate group bonded to monomer A a represents the number of monomers A such that the mass of the polymers of formula (I) is greater than approximately 5,000 da, x represents a substitution rate of the monomers A by the groups X, which is between approximately 20 and 150%, and y represents a substitution rate of the monomers A by the groups Y, which is between approximately 30 and 150%.
    Type: Grant
    Filed: April 12, 2013
    Date of Patent: November 11, 2014
    Inventors: Denis Barritault, Jean-Pierre Caruelle
  • Publication number: 20130287725
    Abstract: A process for treating fibroses including administering a therapeutically effective amount of a pharmaceutical composition which includes at least one biocompatible polymer of the following general formula (I): AaXxYy wherein: A represents a monomer selected from the group consisting of a sugar or —(O—CH2—CH2—CO)—, X represents a carboxyl group bonded to monomer A, Y represents a sulfate or sulfonate group bonded to monomer A a represents the number of monomers A such that the mass of the polymers of formula (I) is greater than approximately 5,000 da, x represents a substitution rate of the monomers A by the groups X, which is between approximately 20 and 150%, and y represents a substitution rate of the monomers A by the groups Y, which is between approximately 30 and 150%.
    Type: Application
    Filed: April 12, 2013
    Publication date: October 31, 2013
    Inventors: Denis BARRITAULT, Jean-Pierre CARUELLE
  • Patent number: 8476220
    Abstract: A process for treating fibroses including administering a therapeutically effective amount of a pharmaceutical composition which includes at least one biocompatible polymer of the following general formula (I): AaXxYy wherein: A represents a monomer selected from the group consisting of a sugar or —(O—CH2—CH2—CO)—, X represents a carboxyl group bonded to monomer A and is contained within a group according to the following formula: —R—COO—R?, in which R is a bond or an aliphatic hydrocarbon chain, optionally branched and/or unsaturated, and which can contain one or more aromatic rings except for benzylamine and benzylamine sulfonate, and R? represents a hydrogen atom or a cation, Y represents a sulfate or sulfonate group bonded to monomer A and is contained within a group according to one of the following formulas: —R—O—SO3—R?, —R—N—SO3—R?, —R—SO3—R?, in which R is a bond or an aliphatic hydrocarbon chain, optionally branched and/or unsaturated, and which can contain one or more aromatic rings except for benzy
    Type: Grant
    Filed: June 14, 2011
    Date of Patent: July 2, 2013
    Inventors: Denis Barritault, Jean-Pierre Caruelle
  • Publication number: 20110243881
    Abstract: A process for treating fibroses including administering a therapeutically effective amount of a pharmaceutical composition which includes at least one biocompatible polymer of the following general formula (I): AaXxYy wherein: A represents a monomer selected from the group consisting of a sugar or —(O—CH2—CH2—CO)—, X represents a carboxyl group bonded to monomer A and is contained within a group according to the following formula: —R—COO—R?, in which R is a bond or an aliphatic hydrocarbon chain, optionally branched and/or unsaturated, and which can contain one or more aromatic rings except for benzylamine and benzylamine sulfonate, and R? represents a hydrogen atom or a cation, Y represents a sulfate or sulfonate group bonded to monomer A and is contained within a group according to one of the following formulas: —R—O—SO3—R?, —R—N—SO3—R?, —R—SO3—R?, in which R is a bond or an aliphatic hydrocarbon chain, optionally branched and/or unsaturated, and which can contain one or more aromatic rings except for benzy
    Type: Application
    Filed: June 14, 2011
    Publication date: October 6, 2011
    Inventors: Denis Barritault, Jean-Pierre Caruelle
  • Patent number: 7998922
    Abstract: A biocompatible polymer constituted by a sequence of identical or different components of the general formula (I): AaXxYy, in which A represents a monomer, X represents a carboxyl group fixed on a monomer A, Y represents a sulfate or sulfonate group fixed on a monomer A; a represents the number of monomers A, x represents the substitution rate of the set of monomers A by the groups X, y represents the substitution rate of the set of monomers A by the groups Y. The invention also pertains to the pharmaceutical or diagnostic compositions containing at least one polymer of general formula (I).
    Type: Grant
    Filed: October 28, 2003
    Date of Patent: August 16, 2011
    Inventors: Denis Barritault, Jean-Pierre Caruelle
  • Publication number: 20090012040
    Abstract: A process for treating fibroses including administering a therapeutically effective amount of a pharmaceutical composition which includes at least one biocompatible polymer of the following general formula (I): AaXxYy wherein: A represents a monomer selected from the group consisting of a sugar or —(O—CH2—CH2—CO)—, X represents a carboxyl group bonded to monomer A and is contained within a group according to the following formula: —R—COO—R?, in which R is a bond or an aliphatic hydrocarbon chain, optionally branched and/or unsaturated, and which can contain one or more aromatic rings except for benzylamine and benzylamine sulfonate, and R? represents a hydrogen atom or a cation, Y represents a sulfate or sulfonate group bonded to monomer A and is contained within a group according to one of the following formulas: —R—O—SO3—R?, —R—N—SO3—R?, —R—SO3—R?, in which R is a bond or an aliphatic hydrocarbon chain, optionally branched and/or unsaturated, and which can contain one or more aromatic rings except for benzy
    Type: Application
    Filed: September 17, 2008
    Publication date: January 8, 2009
    Inventors: Denis Barritault, Jean-Pierre Caruelle
  • Publication number: 20040131583
    Abstract: A biocompatible polymer constituted by a sequence of identical or different components of the general formula (I): AaXxYy, in which A represents a monomer, X represents a carboxyl group fixed on a monomer A, Y represents a sulfate or sulfonate group fixed on a monomer A; a represents the number of monomers A, x represents the substitution rate of the set of monomers A by the groups X, y represents the substitution rate of the set of monomers A by the groups Y. The invention also pertains to the pharmaceutical or diagnostic compositions containing at least one polymer of general formula (I).
    Type: Application
    Filed: October 28, 2003
    Publication date: July 8, 2004
    Inventors: Denis Barritault, Jean-Pierre Caruelle
  • Patent number: 6689741
    Abstract: A biocompatible polymer constituted by a sequence of identical or different components of the general formula (I): AaXxYy, in which A represents a monomer, X represents a carboxyl group fixed on a monomer A, Y represents a sulfate or sulfonate group fixed on a monomer A; a represents the number of monomers A, x represents the substitution rate of the set of monomers A by the groups X, y represents the substitution rate of the set of monomers A by the groups Y. The invention also pertains to the pharmaceutical or diagnostic compositions containing at least one polymer of general formula (I).
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: February 10, 2004
    Inventors: Denis Barritault, Jean-Pierre Caruelle
  • Patent number: 6573251
    Abstract: Use of at least one polymer or one biopolymer called HBGFPP, specifically protecting the growth factors of FGFs and beta TGFs families from tryptic degradation in the manufacture of a drug for the treatment of lesions of the nervous system.
    Type: Grant
    Filed: November 30, 2000
    Date of Patent: June 3, 2003
    Inventors: Denis Barritault, Jean-Pierre Caruelle, Ahmed Aamiri, Jean Gautron
  • Publication number: 20010023246
    Abstract: Use of at least one polymer or one biopolymer called HBGFPP, specifically protecting the growth factors of FGFs and beta TGFs families from tryptic degradation in the manufacture of a drug for the treatment of lesions of the nervous system.
    Type: Application
    Filed: November 30, 2000
    Publication date: September 20, 2001
    Inventors: Denis Barritault, Jean-Pierre Caruelle, Ahmed Aamiri, Jean Gautron
  • Publication number: 20010021758
    Abstract: A biocompatible polymer constituted by a sequence of identical or different components of the general formula (I): AaXxYy, in which A represents a monomer, X represents a carboxyl group fixed on a monomer A, Y represents a sulfate or sulfonate group fixed on a monomer A; a represents the number of monomers A, x represents the substitution rate of the set of monomers A by the groups X, y represents the substitution rate of the set of monomers A by the groups Y. The invention also pertains to the pharmaceutical or diagnostic compositions containing at least one polymer of general formula (I).
    Type: Application
    Filed: January 19, 2001
    Publication date: September 13, 2001
    Inventors: Denis Barritault, Jean-Pierre Caruelle
  • Patent number: 5852003
    Abstract: Use of at least one polymer or one biopolymer, called HBGFPP, specifically protecting the growth factors of the FGF and beta TGF families from tryptic degradation in the manufacture of a drug for the treatment of muscular tissues.
    Type: Grant
    Filed: January 3, 1997
    Date of Patent: December 22, 1998
    Assignee: Societe Valbiofrance
    Inventors: Denis Barritault, Jean-Pierre Caruelle, Pascal Desgranges, Jean Gautron, Anne Meddahi
  • Patent number: 5852004
    Abstract: Use of at least one polymer or one biopolymer, called HBGFPPs, specifically protecting the growth factors of families of FGFs and beta TGFs from tryptic degradation and not significantly inhibiting coagulation, in the manufacture of a drug for the treatment of lesions of the digestive tract and of primary or secondary derived tissues of the endoderm and the mesoderm.
    Type: Grant
    Filed: December 30, 1996
    Date of Patent: December 22, 1998
    Assignee: Societe Valbiofrance
    Inventors: Denis Barritault, Jean-Pierre Caruelle, Anne Meddahi
  • Patent number: 5693625
    Abstract: Compositions useful for regenerating cells and tissues comprise at least one functionalized dextran which has been substituted with carboxymethyl, benzylamide, or benzylamide sulfonate. These dextrans can be used alone or in combination with acid or basic fibroblast growth factors to enhance tissue or cell regeneration. Additionally, these dextrans enhance the stability of acid or basic fibroblast growth factors.
    Type: Grant
    Filed: March 24, 1994
    Date of Patent: December 2, 1997
    Assignee: Therapeutiques Substitutives
    Inventors: Denis Barritault, Jacqueline Jozefonvicz, Michele Tardieu, Faouzi Slaoui, Jean-Pierre Caruelle, Jose Courty