Patents by Inventor Jean-Pierre Clamme

Jean-Pierre Clamme has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA INTERFERENCE DELIVERY FORMULATION AND METHODS FOR MALIGNANT TUMORS
    Publication number: 20240141342
    Abstract: A method for ameliorating or treating a malignant tumor by administering a therapeutically effective amount of a formulation containing RNAi agents. A formulation for use in distributing RNAi molecules targeted to a human GST-? for treating a malignant tumor in a subject. The formulation may include nanoparticles composed of an ionizable lipid, a DSPE lipid, and additional lipids. A drug product may be made by lyophilization of the formulation.
    Type: Application
    Filed: April 11, 2023
    Publication date: May 2, 2024
    Inventors: Bharat Majeti, Jean-Pierre Clamme, Li Wang, Roger C. Adami, Wenbin Ying
  • RNA interference delivery formulation and methods for malignant tumors
    Patent number: 11708575
    Abstract: This invention provides formulations for use in distributing RNAi molecules targeted to a human GST-? for treating a malignant tumor in a subject. The formulation can include nanoparticles composed of an ionizable lipid, a DSPE lipid, and additional lipids. A drug product can be made by lyophilization of the formulation. This invention further provides methods for ameliorating or treating a malignant tumor by administering a therapeutically effective amount of a formulation containing the RNAi agents.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: July 25, 2023
    Assignee: Nitto Denko Corporation
    Inventors: Bharat Majeti, Jean-Pierre Clamme, Li Wang, Roger C. Adami, Wenbin Ying
  • RNA INTERFERENCE DELIVERY FORMULATION AND METHODS FOR MALIGNANT TUMORS
    Publication number: 20200157540
    Abstract: This invention provides formulations for use in distributing RNAi molecules targeted to a human GST-? for treating a malignant tumor in a subject. The formulation can include nanoparticles composed of an ionizable lipid, a DSPE lipid, and additional lipids. A drug product can be made by lyophilization of the formulation. This invention further provides methods for ameliorating or treating a malignant tumor by administering a therapeutically effective amount of a formulation containing the RNAi agents.
    Type: Application
    Filed: November 15, 2019
    Publication date: May 21, 2020
    Inventors: Bharat Majeti, Jean-Pierre Clamme, Li Wang, Roger C. Adami, Wenbin Ying