Abstract: The invention relates to peptide derivatives modeled on the basis of pepstatin.These derivatives inhibit renin and acid proteases.

Abstract: The invention relates to pepstatin analogs which inhibit renin and acid proteases.These analogs are particularly suitable for the treatment of arterial tension.

Abstract: The present invention relates to derivatives of tryptamine of formula: ##STR1## in which: R.sub.1 represents a CH.sub.2 OH group, a --C.tbd.N group, ##STR2## or a --COOR.sub.6 group in which R.sub.4, R.sub.5 and R.sub.6 denote a lower alkyl group or hydrogen;R.sub.2 represents hydrogen or a C.tbd.N group;R.sub.3 denotes hydrogen, a CH.sub.3 group or a CH.sub.2 OH group, and the addition salts of the products of formula I with the pharmaceutically acceptable, mineral or organic acids. It also relates to a process for preparing said compounds and to the drugs active on the cardiovascular system, containing said compounds.

Abstract: The present invention relates to peptide derivatives of the general formula:R--X--Y--Statyl.sub.1 --Ala--Statyl.sub.2 --R' (1),in which:Statyl.sub.1 and Statyl.sub.2 represent the radical derived from the aminoacid statine,R denotes a hydrogen atom or an acylating group attached to the terminal amino group of the aminoacid X--,X and Y, which are identical or different, denote aminoacids of the L or D configuration if a center of asymmetry exists in the molecule, and optionally protected in their side chain, with the proviso that X and Y cannot simultaneously denote valine, andR' denotes OH, O-lower alkyl, NH.sub.2 or a group NH-R.sub.1, in which R.sub.1 represents a lower alkyl or lower aralkyl group.It also relates to a process for the preparation of the products of the formula (1) and to the medicaments containing a product of the formula (1) as the active principle.