Patents by Inventor Jean-Pierre Genet
Jean-Pierre Genet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6878665Abstract: The invention relates to novel diphosphines, in optically pure or racemic form, of formula (I): in which: R1 and R2 are a (C5-C7)cycloalkyl group, an optionally substituted phenyl group or a 5-membered heteroaryl group; and A is (CH2—CH2) or CF2. The invention further relates to the use of a compound of formula (I) as a ligand for the preparation of a metal complex useful as a chiral catalyst in asymmetric catalysis, and to the chiral metal catalysts comprising at least one ligand of formula (I).Type: GrantFiled: September 16, 2002Date of Patent: April 12, 2005Assignee: SynkemInventors: Sébastien Duprat de Paule, Nicolas Champion, Virginie Vidal, Jean-Pierre Genet, Philippe Dellis
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Publication number: 20040260101Abstract: The invention relates to novel diphosphines, in optically pure or racemic form, of formula (I): 1Type: ApplicationFiled: March 23, 2004Publication date: December 23, 2004Inventors: Sebastien Duprat De Paule, Nicolas Champion, Virginie Vidal, Jean-Pierre Genet, Philippe Dellis
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Publication number: 20040138470Abstract: Novel chiral diphosphines (R) or (S), and their use as optically active ligand for preparing diphosphino-metallic complexes, and the diphosphino-metallic complexes containing said chiral diphosphines (R) or (S), and the use of the diphosphino-metallic complexes as catalyst in asymmetric catalysis of unsaturated compounds bearing functional groups.Type: ApplicationFiled: November 20, 2003Publication date: July 15, 2004Inventors: Jean-Pierre Genet, Angela Marinetti, Guillaume Michaud, Michel Bulliard
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Patent number: 6590100Abstract: The present invention provides a process for preparing a polyaromatic compound comprising at least one sequence of two aromatic rings. The process of the invention, which consists in reacting an aromatic compound bearing a leaving group and an arylboronic acid and/or its derivatives in the presence of a base and an effective amount of a nickel catalyst, is characterized in that the reaction is conducted in a reaction solvent which is water optionally in a mixture with an organic solvent and in the presence of an effective amount of a catalyst based on nickel with at least one water-soluble phosphine ligand.Type: GrantFiled: May 15, 2002Date of Patent: July 8, 2003Assignee: Rhodia ChimieInventors: Jean-Christophe Galland, Monique Savignac, Jean-Pierre Genet
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Publication number: 20020173652Abstract: The present invention provides a process for preparing a polyaromatic compound comprising at least one sequence of two aromatic rings.Type: ApplicationFiled: May 15, 2002Publication date: November 21, 2002Inventors: Jean-Christophe Galland, Monique Savignac, Jean-Pierre Genet
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Patent number: 6156889Abstract: The subject matter of the present invention relates to a reagent and a process useful for cleaving a functional group protected by an alkoxycarbonyl group during an organic synthesis. This reagent comprises: a) an aqueous phase; b) a catalyst comprising at least one group VIII element in the periodic table of elements and at least one water-soluble ligand, wherein the group VIII element in the periodic table is maintained in the aqueous phase by the formation of a complex with at least one water-soluble ligand; and c) a nucleophilic compound soluble in the aqueous phase; and optionally d) an organic phase.Type: GrantFiled: October 9, 1998Date of Patent: December 5, 2000Assignee: Rhodia ChimieInventors: Jean-Marie Bernard, Errol Blart, Jean-Pierre Genet, Monique Savignac, Sandrine Lemaire-Audoire
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Patent number: 5874600Abstract: A catalyst of ruthenium (II) which includes bidentate phosphine ligands. The catalyst is obtainable by a process which includes the steps of treating equimolar amounts of an appropriate Ru(II) complex and a bidentate diphosphine ligand with an acid of formula HX, wherein X is a non-coordinating anion. The acid is used in a ratio which does not exceed 2 molar equivalents per mole of Ru(II) complex and the treatment is carried out in a non-coordinating or weakly coordinating solvent and under an inert atmosphere. This catalyst is useful for the preparation of the preferred isomer of HEDIONE, having the (+)-(1R)-cis-configuration.Type: GrantFiled: July 10, 1997Date of Patent: February 23, 1999Assignee: Firmenich SAInventors: Valentin Rautenstrauch, Koenraad P. M. Vanhessche, Jean-Pierre Genet, Jean-Yves Lenoir
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Patent number: 5847117Abstract: The subject matter of the present invention relates to a reagent and a process useful for cleaving a functional group protected by an alkoxycarbonyl group during an organic synthesis. This reagent comprises: a) an aqueous phase; b) a catalyst comprising at least one group VIII element in the periodic table of elements and at least one water-soluble ligand, wherein the group VIII element in the periodic table is maintained in the aqueous phase by the formation of a complex with at least one water-soluble ligand; and c) a nucleophilic compound soluble in the aqueous phase; and optionally d) an organic phase.Type: GrantFiled: August 18, 1993Date of Patent: December 8, 1998Assignee: Rhone-Poulenc ChimieInventors: Jean-Marie Bernard, Errol Blart, Jean-Pierre Genet, Monique Savignac, Sandrine Lemaire-Audoire
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Patent number: 5773617Abstract: The present invention relates to a reagent and to a process which are useful, when carrying out an organic synthesis, for cleaving an allylic group from a function which is protected with the latter.This reagent is defined in that it contains:a) a solvent system;b) a catalyst containing at least one element from column VIII of the Periodic Table of the Elements, the said element from column VIII of the Periodic Table being coordinated with at least one coordination agent which is soluble in the said solvent system;c) a compound which is at least partially soluble in the said solvent system and which contains at least one nucleophilic function.Application to organic synthesis.Type: GrantFiled: February 22, 1996Date of Patent: June 30, 1998Assignee: Rhone-Poulenc ChimieInventors: Jean-Marie Bernard, Errol Blart, Jean-Pierre Genet, Sandrine Lemaire-Audoire, Monique Savignac
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Patent number: 5614641Abstract: The present invention concerns a process for enantioselective catalytic hydrogenation of the ketone C.dbd.O double bond to a secondary alcohol function, said process using a neutral ruthenium complex as the catalyst and a compound containing a C.dbd.O group as the substrate to be hydrogenated, characterised in that it comprises hydrogenation of the substrate using a diallyl (diphosphino) ruthenium compound with formula ##STR1## where al preferably represents CH.sub.2 CH.dbd.CH.sub.2 or CH.sub.2 C(CH.sub.3).dbd.CH.sub.2,Q represents a hydrocarbon bridge containing at least two catenary carbon atoms and which can contain one to four catenary heteroatoms selected from O, S, N and Si,R.sup.1 to R.sup.4 may be identical or different and each represents a C.sub.1 -C.sub.18 alkyl, C.sub.5 -C.sub.7 cycloalkyl or C.sub.6 -C.sub.12 aryl group.Type: GrantFiled: March 9, 1995Date of Patent: March 25, 1997Assignee: Elf AquitaineInventors: Jean-Pierre Genet, Sylvain Juge, Jean-Alex Laffitte, Catherine Pinel, Serge Mallart
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Patent number: 5426216Abstract: The present invention relates to a process for the hydrogenation of ethylenically unsaturated organic compounds. This process is carried out in a homogeneous medium containing a hydrogenation catalyst formed by a complex of ruthenium with a phosphine, which comprises two allylic groups as ligands on the Ru.Type: GrantFiled: August 12, 1993Date of Patent: June 20, 1995Assignee: Society Nationale Elf AquitaineInventors: Jean-Pierre Genet, Sylvain Juge, Jean A. Laffitte, Catherine Pinel, Sergio Mallart
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Patent number: 5324850Abstract: Method for the preparation of a chiral catalyst, comprised of an organic complex of ruthenium and phosphorus, consisting in heating a complex of ruthenium with a phosphine, within an organic liquid, inert in relation to substances in presence, the heated complex being based on a diene and an allylic compound; the product obtained following the heating is subjected to the action of an acid in an organic solvent.Type: GrantFiled: February 21, 1992Date of Patent: June 28, 1994Assignee: Societe Nationale Elf AquitaineInventors: Sylvain Juge, Jean-Pierre Genet, Sergio Mallart
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Patent number: 5264602Abstract: This invention is concerned with new chiral diphosphinite-borane compound of the formula ##STR1## wherein R.sup.1 and R.sup.2, identical or different, represent each a C.sub.1 -C.sub.18 alkyl, C.sub.5 -C.sub.18 cycloalkyl, C.sub.7 -C.sub.18 aralkyl or C.sub.6 -C.sub.14 aryl group which can bear functional groups,R.sup.3 represents a C.sub.1 -C.sub.18 alkyl, C.sub.5 -C.sub.18 cycloalkyl, C.sub.7 -C.sub.18 aralkyl, C.sub.6 -C.sub.14 aryl, C.sub.1 -C.sub.18 alkoxy, C.sub.5 -C.sub.18 cycloalkyloxy, C.sub.7 -C.sub.18 aralkyloxy or C.sub.6 -C.sub.14 aryloxy group,Z represents a bridge linking the two phosphinite P atoms, said bridge being (i) a hydrocarbon chain having from 1 to 12 catenary C atoms or (ii) a heterohydrocarbon chain comprising from 1 to 12 catenary C atoms and at least one catenary heteroatom selected from the group consisting of O, S, Si, P and N.These chiral compounds are useful in the manufacture of chiral diphosphine compounds.Type: GrantFiled: January 9, 1992Date of Patent: November 23, 1993Assignee: Societe Nationale Elf AquitaineInventors: Sylvain Juge, Jean-Pierre Genet, Jean-Alex Laffitte, Massoud Stephan
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Patent number: 5166389Abstract: New chemical product, constituted by an organic phosphorus compound of the structure ##STR1## where Q is an N or O atom, T is an alkylene or arylene, possibly carrying substituents, or not existing, while R.sup.1 to R.sup.7, the same or different, are H or aliphatic, cycloaliphatic and/or arylic hydrocarbon radicals, possibly substituted, R.sup.3 not existing when Q is oxygen. This product is used as an intermediate in the preparation of different derivatives of phosphinous acid.Type: GrantFiled: July 29, 1991Date of Patent: November 24, 1992Assignee: Societe Nationale Elf AquitaineInventors: Sylvain Juge, Jean-Pierre Genet
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Patent number: 5084582Abstract: The invention relates to a method of oxidizing epoxyalcohols, in a medium containing an organic solvent and water, by means of a solid oxidizing compound, in the presence of a catalyst based on a ruthenium salt. The proportion of water relative to that of organic solvent is sufficiently small for at least the major part of the oxidizing compound to remain in the solid state in the reaction medium, which is heterogeneous.Type: GrantFiled: January 18, 1991Date of Patent: January 28, 1992Assignee: Societe Nationale Elf AquitaineInventors: Jean-Pierre Genet, Dominique Pons, Sylvain Juge
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Patent number: 5043465Abstract: New organic phosphorus compounds, comprised of hetero-phosphacycloalkanes whose phosphorus atom forms a complex with a borane. They can be prepared by the action of a borane on a hetero-phosphacycloalkane, within a solvent, at temperatures ranging from -20.degree. to +60.degree. C. Their transformation into other derivatives, phosphinites or phosphines in particular, can be carried out without any modification in the chirality of the initial complex. An especially useful application is their conversion into highly optically active phosphines, used in particular as catalysts in various reactions.Type: GrantFiled: December 28, 1989Date of Patent: August 27, 1991Assignee: Societe Nationale Elf AquitaineInventors: Sylvain Juge, Jean-Pierre Genet
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Patent number: 4952728Abstract: New chemical product, constituted by an organic phosphorus compound of the structure ##STR1## where Q is an N or O atom, T is an alkylene or arylene, possibly carrying substituents, or not existing, while R.sup.1 to R.sup.7, the same or different, are H or aliphatic, cycloaliphatic and/or arylic hydrocarbon radicals, possibly substituted, R.sup.3 not existing when Q is oxygen.This product is used as an intermediate in the preparation of different derivatives of phosphinous acid.Type: GrantFiled: August 26, 1987Date of Patent: August 28, 1990Assignee: Societe Nationale Elf AquitaineInventors: Sylvain Juge, Jean-Pierre Genet
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Patent number: 4307244Abstract: Novel penten-2-yl derivatives of the formula in the trans form ##STR1## wherein R is selected from the group consisting of hydrogen and acetyl and to a novel process for the preparation of methyl 2,2-dimethyl-3-(2'-methyl-propenyl)-cyclopropane-1,1-dicarboxylate which is an intermediate for chrysanthemic acid.Type: GrantFiled: August 11, 1980Date of Patent: December 22, 1981Assignee: Roussel UclafInventors: Jacqueline Ficini, Jean-Pierre Genet
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Patent number: 4245112Abstract: Novel penten-2-yl derivatives of the formula in the trans form ##STR1## wherein R is selected from the group consisting of hydrogen and acetyl and to a novel process for the preparation of methyl 2,2-dimethyl-3-(2'-methyl-propenyl)-cyclopropane-1,1-dicarboxylate which is an intermediate for chrysanthemic acid.Type: GrantFiled: November 27, 1979Date of Patent: January 13, 1981Assignee: Roussel UclafInventors: Jacqueline Ficini, Jean-Pierre Genet