Abstract: The invention concerns a device and a method for concentrating pathogenic germs potentially present in blood products or derivatives and for detecting said germs comprising the following steps: (a) subjecting a sample of said blood product to a blood cell aggregating treatment, (b) eliminating the aggregates formed at step (a) by passing the treated sample over a first filter allowing through the contaminating germs but not the cell aggregates, (c) selectively lyzing the residual cells of the filtrate obtained at step (b), (d) recuperating the contaminating germs by passing the lysate of step (c) over a second filter to detect the contaminating germs possibly trapped.

Abstract: The invention concerns a device for preparing a body fluid for a bacteriological analysis thereof comprising a container provided with a chamber (4) wherein a piston (5) is mobile between an opening position and a closing position, the chamber (4) including a separation zone (7) and means for introducing (15, 16) a fluid into said chamber and the piston (5) including a closure means (8) co-operating with the separation zone (7) so as to define an upper volume (9) and a lower volume (10) on either side of said zone, the upper volume (9) and the lower volume (10) mutually communicating when the piston (5) is in opening position and being tightly isolated from each other when the piston (5) is in closing position. The invention also concerns a preparation method using such a device (1).

Abstract: The invention concerns a device and a method for concentrating pathogenic germs potentially present in blood products or derivatives and for detecting said germs comprising the following steps: (a) subjecting a sample of said blood product to a blood cell aggregating treatment, (b) eliminating the aggregates formed at step (a) by passing the treated sample over a first filter allowing through the contaminating germs but not the cell aggregates, (c) selectively lyzing the residual cells of the filtrate obtained at step (b), (d) recuperating the contaminating germs by passing the lysate of step (c) over a second filter to detect the contaminating germs possibly trapped.

Abstract: The invention concerns a device and a method for concentrating pathogenic germs potentiaily present in blood products or derivatives and for detecting said germs comprising the following steps: (a) subjecting a sample of said blood product to a blood cell aggregating treatment, (b) eliminating the aggregates formed at step (a) by passing the treated sample over a first filter allowing through the contaminating germs but not the cell aggregates, (c) selectively lyzing the residual cells of the filtrate obtained at step (b), (d) recuperating the contaminating germs by passing the lysate of step (c) over a second filter to detect the contaminating germs possibly trapped.

Abstract: A method and device for continuously drawing and mixing liquid samples originating from at least two different containers are described. The device comprises a mixing chamber, which is connected to each of the containers. The device is characterized in that it comprises, between the container and the mixing chamber, at least one intermediate sample chamber for each container, being connected in order to transfer all or a portion of the sampled liquid to the mixing chamber. The device has a vertical configuration.

Abstract: The present invention relates to a method for extracting DNA from microorganisms possibly present in a blood sample, comprising the following steps: i) filtration of a blood sample through a filtration membrane, the pores of which have a diameter ranging from 0.01 ?m to 50 ?m, in particular from 0.1 ?m to 10 ?m, and most particularly from 0.2 ?m to 1 ?m; ii)) washing of said filtration membrane; and iii) extraction of the deoxyribonucleic acids from the microorganisms possibly present on said filtration membrane.

Abstract: The invention concerns a device for preparing a body fluid for a bacteriological analysis thereof comprising a container provided with a chamber (4) wherein a piston (5) is mobile between an opening position and a closing position, the chamber (4) including a separation zone (7) and means for introducing (15, 16) a fluid into said chamber and the piston (5) including a closure means (8) co-operating with the separation zone (7) so as to define an upper volume (9) and a lower volume (10) on either side of said zone, the upper volume (9) and the lower volume (10) mutually communicating when the piston (5) is in opening position and being tightly isolated from each other when the piston (5) is in closing position. The invention also concerns a preparation method using such a device (1).

Abstract: A method and device for continuously drawing and mixing liquid samples originating from at least two different containers are described. The device comprises a mixing chamber, which is connected to each of the containers. The device is characterized in that it comprises, between the container and the mixing chamber, at least one intermediate sample chamber for each container, being connected in order to transfer all or a portion of the sampled liquid to the mixing chamber. The device has a vertical configuration.

Abstract: A process for detecting microorganisms present in a biological fluid including a) contacting a sample of the biological fluid with a reaction environment comprising a marking agent that is a derivative of cyanines and at least one reactant of cellular penetration of the membrane of the microorganisms, b) filtering the sample on a filter capable of retaining the marked microorganisms present in the sample, and c) detecting the marked microorganisms retained in the filter in stage (b).

Abstract: A method for detecting contaminating microbes possibly present in a blood product including blood cells including a) subjecting a sample of the blood product to an aggregation treatment of the blood cells, b) substantially eliminating aggregates formed in step (a) by passage of the sample over a first filter allowing passage of contaminating microbes, but not cell aggregates, c) selectively lysing residual cells of the filtrate obtained in step (b), d) recovering the contaminating microbes by passage of the lysate from step (c) over a second filter allowing passage of cellular debris, e) adding a marker agent of the contaminating microbes either during step (a) or step (c), and f) analyzing material on the second filter to detect labeled contaminating microbes possibly retained by the second filter; and a device for concentrating contaminating microbes possibly present in a blood product including blood cells including a first watertight, sterile tank containing at least one blood cell aggregation agent and,