Patents by Inventor Jean-Pierre J. Issa

Jean-Pierre J. Issa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminothiazole compounds and methods using same
    Patent number: 11787794
    Abstract: The present invention includes novel aminothiazole compounds of formula (I), which are useful in preventing or treating cancer in a subject in need thereof.
    Type: Grant
    Filed: November 7, 2019
    Date of Patent: October 17, 2023
    Assignee: Temple University-Of The Commonwealth System of Higher Education
    Inventors: Jean-Pierre J. Issa, Hanghang Zhang, Magid Abou-Gharbia, Wayne E. Childers, George C. Morton
  • Bridged bicycloalkyl-substituted aminothiazoles and their methods of use
    Patent number: 10941126
    Abstract: The present invention includes novel bridged bicycloalkyl-substituted aminothiazole compounds useful in preventing or treating cancer in a subject in need thereof. The present invention also includes methods of preventing or treating cancer in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of the invention.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: March 9, 2021
    Assignee: TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Wayne C. Childers, Magid A. Abou-Gharbia, George C. Morton, Jean-Pierre J. Issa, Hanghang Zhang
  • Novel Aminothiazole Compounds and Methods Using Same
    Publication number: 20200071314
    Abstract: The present invention includes novel aminothiazole compounds useful in preventing or treating cancer in a subject in need thereof. The present invention also includes methods of preventing or treating cancer in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of the invention.
    Type: Application
    Filed: November 7, 2019
    Publication date: March 5, 2020
    Inventors: Jean-Pierre J. Issa, Hanghang Zhang, Magid Abou-Gharbia, Wayne E. Childers, George C. Morton
  • Aminothiazole compounds and methods using same
    Patent number: 10513516
    Abstract: The present invention includes novel aminothiazole compounds of formula (I) useful in preventing or treating cancer in a subject in need thereof. The present invention also includes methods of preventing or treating cancer in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of the invention.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: December 24, 2019
    Assignee: Temple University—Of The Commonwealth System of Higher Education
    Inventors: Jean-Pierre J. Issa, Hanghang Zhang, Magid Abu-Gharbia, Wayne E. Childers, George C. Morton
  • Novel Bridged Bicycloalkyl-Substituted Aminothiazoles and Their Methods of Use
    Publication number: 20190352272
    Abstract: The present invention includes novel bridged bicycloalkyl-substituted aminothiazole compounds useful in preventing or treating cancer in a subject in need thereof. The present invention also includes methods of preventing or treating cancer in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of the invention.
    Type: Application
    Filed: January 19, 2018
    Publication date: November 21, 2019
    Inventors: Wayne C. Childers, Magid A. Abou-Gharbia, George C. Morton, Jean-Pierre J. Issa, Hanghang Zhang
  • Hypomethylation of TET2 target genes for identifying a curable subgroup of acute myeloid leukemia
    Publication number: 20180312927
    Abstract: The invention provides AML-specific methylation biomarkers (SP140, MCCC1, EHMT1 and MTSS1). In one embodiment, a biomarker is differentially methylated, specifically in AML.
    Type: Application
    Filed: October 19, 2016
    Publication date: November 1, 2018
    Inventors: Jean-Pierre J. Issa, Jumpei Yamazaki
  • Novel Aminothiazole Compounds and Methods Using Same
    Publication number: 20180215750
    Abstract: The present invention includes novel aminothiazole compounds useful in preventing or treating cancer in a subject in need thereof. The present invention also includes methods of preventing or treating cancer in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of the invention.
    Type: Application
    Filed: July 21, 2016
    Publication date: August 2, 2018
    Inventors: Jean-Pierre J. Issa, Hanghang Zhang, Magid Abu-Gharbia, Wayne E. Childers, George C. Morton