Abstract: There is provided a radiographic three-dimensional phantom for inter alia mimicking specific anatomical parts in a computerized tomography scan. Methods are provided for a variety of purposes including detecting a difference between a measured optical deformation of a radiographic three-dimensional phantom pair and a theoretical deformation of the radiographic three-dimensional phantom pair. These three-dimensional phantom can be divided into a plurality of portions, and non-radiopaque markers can be added to the portions. The portions of the three-dimensional phantom can be re-assembled, and images of the three-dimensional phantom can be generated and compared.

Abstract: The present invention offers an alternative for cancer treatment where radiation, thermotherapy, or another therapeutic modality must be delivered to an internal cavity of a subject, for example to treat mouth, anal, cervical, and vaginal cancers. The invention is a new approach that builds on recent results in 3D printing and steerable needle motion planning to create customized implants containing customized curvature-constrained internal channels that fit securely, minimize air gaps, and precisely guide treatment sources through internal printed channels to accurately reach tumors and minimize damage to healthy tissue.

Abstract: The present invention offers an alternative for cancer treatment where radiation, thermotherapy, or another therapeutic modality must be delivered to an internal cavity of a subject, for example to treat mouth, anal, cervical, and vaginal cancers. The invention is a new approach that builds on recent results in 3D printing and steerable needle motion planning to create customized implants containing customized curvature-constrained internal channels that fit securely, minimize air gaps, and precisely guide treatment sources through internal printed channels to accurately reach tumors and minimize damage to healthy tissue.

Abstract: There is provided a radiographic phantom for inter alia mimicking specific anatomical parts in a computerized tomography scan. Methods are provided for a variety of purposes including detecting a difference between a measured optical deformation of a radiographic phantom pair and a theoretical deformation of the radiographic phantom pair.

Abstract: There is provided a radiographic three-dimensional phantom for inter alia mimicking specific anatomical parts in a computerized tomography scan. Methods are provided for a variety of purposes including detecting a difference between a measured optical deformation of a radiographic three-dimensional phantom pair and a theoretical deformation of the radiographic three-dimensional phantom pair. These three-dimensional phantom can be divided into a plurality of portions, and non-radiopaque markers can be added to the portions. The portions of the three-dimensional phantom can be re-assembled, and images of the three-dimensional phantom can be generated and compared.

Abstract: There is provided a radiographic phantom for inter alia mimicking specific anatomical parts in a computerized tomography scan. Methods are provided for a variety of purposes including detecting a difference between a measured optical deformation of a radiographic phantom pair and a theoretical deformation of the radiographic phantom pair.

Abstract: A system includes acquisition of a three-dimensional cone beam image, and determination of a dose to be delivered based on the three-dimensional image and on parameters of a treatment beam to deliver the dose. Some systems may include modification of a three-dimensional cone beam image to correct for scatter radiation, and determination of a dose based on the modified three-dimensional cone beam image.

Abstract: Herein are described methods and tools for acquiring accurately co-registered PET and TRUS images, as well as the construction and use of PET-TRUS prostate phantoms. Ultrasound imaging with a transrectal probe provides anatomical detail in the prostate region that can be accurately co-registered with the sensitive functional information from the PET imaging. Imaging the prostate with both PET and transrectal ultrasound (TRUS) will help determine the location of any cancer within the prostate region. This dual-modality imaging should help provide better detection and treatment of prostate cancer. Multi-modality phantoms are also described.

Abstract: A system includes acquisition of a three-dimensional cone beam image, and determination of a dose to be delivered based on the three-dimensional image and on parameters of a treatment beam to deliver the dose. Some systems may include modification of a three-dimensional cone beam image to correct for scatter radiation, and determination of a dose based on the modified three-dimensional cone beam image.

Abstract: A radioactive implant characterized by a biological effectiveness comparable to that of palladium-103 and, simultaneously, by a half-life of the order of that of iodine-125. More specifically, the present invention provides a radioactive implant having improved biological effectiveness, by lowering the average energy of the photon spectrum of a relatively long half-life radioisotope element using x-ray fluorescence. Selection of a fluorescent material within elements having an atomic number between 39 and 45, preferably between 40 and 42, for surrounding a radioactive inner core comprising the radioisotope element, is described.