Patents by Inventor Jean Provost

Jean Provost has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12066312
    Abstract: A method for determining a flow rate and/or a concentration of particles of a fluid flowing in a chamber, which includes the steps of: producing an ultrasound beam of a given frequency with a first transducer such that all fluid components traveling through an intersection region between the ultrasound beam and the chamber are insonated by the first transducer; receiving Doppler-shifted ultrasound signals generated by the fluid components in the insonated region of the chamber with a second transducer; acquiring the ultrasound signals received by the second transducer during an acquisition time; obtaining a Doppler Power Spectrum of the acquired ultrasound signals; and determining the flow rate and/or the concentration of particles of the fluid by adjustment between, on the one hand, the obtained Doppler Power Spectrum and, on the other hand, a model of the Doppler Power Spectrum.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: August 20, 2024
    Assignees: AENITIS TECHNOLOGIES, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ÉCOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
    Inventors: Jean Provost, Jérémie Gachelin, Baptiste Pialot, Olivier Couture, Emmanuel Vincent
  • Patent number: 11940578
    Abstract: An imaging method including: a) acquiring N successive positron emission tomography (PET) low resolution images ?i and simultaneously, N successive Ultrafast Ultrasound Imaging (UUI) images Ui of a moving object; b) determining from each UUI image Ui, the motion vector fields Mi that corresponds to the spatio-temporal geometrical transformation of the motion of the object; c) obtaining a final estimated high resolution image H of the object by iterative determination of a high resolution image Hn+1 obtained by applying several correction iterations to a current estimated high resolution image Hn, n being the number of iterations, starting from an initial estimated high resolution image H1 of the object, each correction iteration including at least: i) warping the estimated high resolution image Hn using the motion vector fields Mi to determine a set of low resolution reference images Lni; ii) determining a differential image Di by difference between each PET image ?i and the corresponding low resolution re
    Type: Grant
    Filed: January 28, 2021
    Date of Patent: March 26, 2024
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ DE PARIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
    Inventors: Bertrand Tavitian, Mickaël Tanter, Mailyn Perez-Liva, Joaquin Lopez Herraiz, Jean Provost
  • Publication number: 20230309944
    Abstract: The invention relates to a method for determining at least one property of an object, the method comprising a step of: a) obtaining first data relative to the object by an ultrasound imaging technique imaging the object at a frame rate superior to 300 Hz, characterized in that the method further comprises a step of: b) obtaining second data relative to the object by imaging the object with at least one of a X-ray and a ?-ray, and c) determining the at least one property of the object based on the first data and the second data.
    Type: Application
    Filed: June 7, 2023
    Publication date: October 5, 2023
    Inventors: Jean PROVOST, Anikitos GAROFALAKIS, Mathieu PERNOT, Mickaël TANTER, Bertrand TAVITIAN, Thomas VIEL
  • Publication number: 20230301630
    Abstract: There is provided a method for ultrasound imaging comprising applying an ultrasound modulation wave at a fixed frequency F1 and a period P1 to a target in a body, the body having received an injection of microbubbles through a fluid, the modulation wave causing the microbubbles to undergo stable acoustic cavitation, emitting, toward the target and concurrently with the modulation wave, ultrasound imaging pulses centered at a frequency F2 and having a pulse repetition period of n*P1 and a pulse delay of m*P1/k, where the pulse delay varies with m, m<k, and k>1, detecting reflections of the ultrasound pulses by the microbubbles after each emission for a duration corresponding to a maximum depth of the target, and forming ultrasound images from the reflections.
    Type: Application
    Filed: August 5, 2021
    Publication date: September 28, 2023
    Inventors: Simon BLAIS, Jonathan POREE, Jean PROVOST
  • Publication number: 20230301623
    Abstract: There is provided a method and a system for ultrasound imaging in presence of relative motion between a body and an imaging probe. A plurality of Eulerian-based ultrasound images of the body acquired at successive times T with the imaging probe is obtained. Lagrangian coordinates for the body are computed using data from the Eulerian-based ultra-sound images. Lagrangian-based ultrasound images of the body are formed by providing the data from the Eulerian-based ultrasound images in the Lagrangian coordinate system.
    Type: Application
    Filed: August 5, 2021
    Publication date: September 28, 2023
    Inventors: Philippe CORMIER, Jonathan POREE, Jean PROVOST
  • Publication number: 20210396559
    Abstract: A method for determining a flow rate and/or a concentration of particles of a fluid flowing in a chamber, which includes the steps of: producing an ultrasound beam of a given frequency with a first transducer such that all fluid components traveling through an intersection region between the ultrasound beam and the chamber are insonated by the first transducer; receiving Doppler-shifted ultrasound signals generated by the fluid components in the insonated region of the chamber with a second transducer; acquiring the ultrasound signals received by the second transducer during an acquisition time; obtaining a Doppler Power Spectrum of the acquired ultrasound signals; and determining the flow rate and/or the concentration of particles of the fluid by adjustment between, on the one hand, the obtained Doppler Power Spectrum and, on the other hand, a model of the Doppler Power Spectrum.
    Type: Application
    Filed: October 18, 2019
    Publication date: December 23, 2021
    Applicants: AENITIS TECHNOLOGIES, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ÉCOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
    Inventors: Jean PROVOST, Jérémie GACHELIN, Baptiste PIALOT, Olivier COUTURE, Emmanuel VINCENT
  • Patent number: 11096660
    Abstract: Ultrasound methods, devices, and systems are described which support a useful compromise in terms of spatial resolution and temporal resolution for capturing motion in tissue structures. Tissue engineering articles, methods, systems, and devices which employ ultrasound to deliver biological agents to selected regions of a tissue scaffold, deliver mechanical stimulation to cells growing in a tissue scaffold, and enhance the perfusion of fluids through tissue scaffolds.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: August 24, 2021
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Elisa E. Konofagou, Jean Provost, Jianwen Luo, Stanley J. Okrasinski, Stéphane Thiébaut, Vu Thanh-Hieu Nguyen
  • Publication number: 20210239863
    Abstract: An imaging method including: a) acquiring N successive positron emission tomography (PET) low resolution images ?i and simultaneously, N successive Ultrafast Ultrasound Imaging (UUI) images Ui of a moving object; b) determining from each UUI image Ui, the motion vector fields Mi that corresponds to the spatio-temporal geometrical transformation of the motion of the object; c) obtaining a final estimated high resolution image H of the object by iterative determination of a high resolution image Hn+1 obtained by applying several correction iterations to a current estimated high resolution image Hn, n being the number of iterations, starting from an initial estimated high resolution image H1 of the object, each correction iteration including at least: i) warping the estimated high resolution image Hn using the motion vector fields Mi to determine a set of low resolution reference images Lni; ii) determining a differential image Di by difference between each PET image ?i and the corresponding low resolution re
    Type: Application
    Filed: January 28, 2021
    Publication date: August 5, 2021
    Inventors: Bertrand TAVITIAN, Mickaël TANTER, Mailyn PEREZ-LIVA, Joaquin LOPEZ HERRAIZ, Jean PROVOST
  • Publication number: 20210085284
    Abstract: Systems and methods for detecting electromechanical wave propagation within a body structure of a patient in a series of image frames representing movement the body structure are provided. Image data is acquired comprising a series of image frames corresponding to the movement of a body structure. A correlation calculation is performed on the image frames to generate a displacement map representing the relative displacement between the first and second image frames. A video is generated comprising a series of displacement maps. The parameters of movement of the body structure are detected by analysis of the displacement maps. The image acquisition can detect the movement of the body structure without inducing such movement.
    Type: Application
    Filed: May 11, 2020
    Publication date: March 25, 2021
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Elisa E. Konofagou, Jean Provost
  • Patent number: 10687785
    Abstract: Systems and methods for detecting electromechanical wave propagation within a body structure of a patient in a series of image frames representing movement the body structure are provided. Image data is acquired comprising a series of image frames corresponding to the movement of a body structure. A correlation calculation is performed on the image frames to generate a displacement map representing the relative displacement between the first and second image frames. A video is generated comprising a series of displacement maps. The parameters of movement of the body structure are detected by analysis of the displacement maps. The image acquisition can detect the movement of the body structure without inducing such movement.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: June 23, 2020
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERISTY IN THE CITY OF NEW YORK
    Inventors: Elisa E. Konofagou, Jean Provost
  • Publication number: 20200163646
    Abstract: Techniques for mapping behavior of a heart include acquiring a series of two or more images of the heart. The series of images is taken at one or more pixel locations, each pixel location corresponding to a region of the heart. Image data corresponding to the pixel locations can be obtained, and a periodicity of the image data measured for each of the pixel locations over the series of images. The periodicity corresponds to an electromechanical signal of the heart in the region corresponding to the measured one or more pixel locations.
    Type: Application
    Filed: November 7, 2019
    Publication date: May 28, 2020
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Elisa E. Konofagou, Jean Provost, Alok Gambhir, Alexandre Costet, Elaine Wan, Julien Grondin
  • Publication number: 20200107817
    Abstract: The present invention relates to the field of acoustoelectric and acoustooptical imaging methods. It is known a specific example of an acoustoelectric imaging method, in which focused ultrasonic waves are emitted so as to form an image of the current, line by line. However, the acquisition process disclosed is slow, and all the more so because, as the resulting electrical signals are very weak, a high level of averaging is required. Low frame rates are therefore obtained. That is why the inventors worked on an imaging method with improved contrast and resolution. The present invention proposes a method for imaging a medium (10) wherein ultrasound contrast agents (12) are present.
    Type: Application
    Filed: March 22, 2018
    Publication date: April 9, 2020
    Inventors: Jean PROVOST, Mickael TANTER, Béatrice BERTHON
  • Patent number: 10517564
    Abstract: Techniques for mapping behavior of a heart include acquiring a series of two or more images of the heart. The series of images is taken at one or more pixel locations, each pixel location corresponding to a region of the heart. Image data corresponding to the pixel locations can be obtained, and a periodicity of the image data measured for each of the pixel locations over the series of images. The periodicity corresponds to an electromechanical signal of the heart in the region corresponding to the measured one or more pixel locations.
    Type: Grant
    Filed: April 9, 2015
    Date of Patent: December 31, 2019
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Elisa E. Konofagou, Jean Provost, Alok Gambhir, Alexandre Costet, Elaine Wan, Julien Grondin
  • Publication number: 20180271471
    Abstract: The invention relates to a method for determining at least one property of an object, the method comprising a step of: a) obtaining first data relative to the object by an ultrasound imaging technique imaging the object at a frame rate superior to 300 Hz, characterized in that the method further comprises a step of: b) obtaining second data relative to the object by imaging the object with at least one of a X-ray and a ?-ray, and c) determining the at least one property of the object based on the first data and the second data.
    Type: Application
    Filed: September 29, 2016
    Publication date: September 27, 2018
    Inventors: Jean PROVOST, Anikitos GAROFALAKIS, Mathieu PERNOT, Mickaël TANTER, Bertrand TAVITIAN, Thomas VIEL
  • Publication number: 20170148163
    Abstract: Systems and methods for matching a characteristic of multiple sectors of a moving tissue to verify an overlap thereof are disclosed herein. In an exemplary method, tissue data for at least a first sector and a second sector of a moving tissue is acquired. A characteristic of at least a portion of the first and second sectors is estimated from the acquired tissue data, and the estimated characteristics are matched to verify whether a portion of the first sector overlaps with a portion of the second sector. Estimating can include estimating a displacement such as an axial displacement and/or lateral displacements. Estimating can further include estimating a strain, a velocity, a strain rate and/or a stiffness or equivalent.
    Type: Application
    Filed: December 2, 2016
    Publication date: May 25, 2017
    Inventors: Elisa E. Konofagou, Jean Provost
  • Patent number: 9514358
    Abstract: Systems and methods for matching a characteristic of multiple sectors of a moving tissue to verify an overlap thereof are disclosed herein. In an exemplary method, tissue data for at least a first sector and a second sector of a moving tissue is acquired. A characteristic of at least a portion of the first and second sectors is estimated from the acquired tissue data, and the estimated characteristics are matched to verify whether a portion of the first sector overlaps with a portion of the second sector. Estimating can include estimating a displacement such as an axial displacement and/or lateral displacements. Estimating can further include estimating a strain, a velocity, a strain rate and/or a stiffness or equivalent.
    Type: Grant
    Filed: March 21, 2013
    Date of Patent: December 6, 2016
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Elisa Konofagou, Jean Provost
  • Publication number: 20160296203
    Abstract: Ultrasound methods, devices, and systems are described which support a useful compromise in terms of spatial resolution and temporal resolution for capturing motion in tissue structures. Tissue engineering articles, methods, systems, and devices which employ ultrasound to deliver biological agents to selected regions of a tissue scaffold, deliver mechanical stimulation to cells growing in a tissue scaffold, and enhance the perfusion of fluids through tissue scaffolds.
    Type: Application
    Filed: April 8, 2016
    Publication date: October 13, 2016
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Elisa E. KONOFAGOU, Jean PROVOST, Jianwen LUO, Stanley J. OKRASINSKI, Stéphane THIÉBAUT, Vu Thanh-Hieu NGUYEN
  • Publication number: 20160249880
    Abstract: Systems and methods for detecting electromechanical wave propagation within a body structure of a patient in a series of image frames representing movement the body structure are provided. Image data is acquired comprising a series of image frames corresponding to the movement of a body structure. A correlation calculation is performed on the image frames to generate a displacement map representing the relative displacement between the first and second image frames. A video is generated comprising a series of displacement maps. The parameters of movement of the body structure are detected by analysis of the displacement maps. The image acquisition can detect the movement of the body structure without inducing such movement.
    Type: Application
    Filed: February 19, 2016
    Publication date: September 1, 2016
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Elisa E. Konofagou, Jean Provost
  • Publication number: 20160157728
    Abstract: The invention relates to an acoustic-electric imaging method, which includes: a measurement step during which incident ultrasonic waves having different wavefronts are emitted in a medium 1 to be imaged, and at least one electric sensor is used to capture raw electric signals Erawl(t) respectively during the propagation of the incident waves; a step of forming an image, during which an image of the medium including an electric current map is determined from the raw electric signals Erawl(t).
    Type: Application
    Filed: July 21, 2014
    Publication date: June 9, 2016
    Inventors: Mickaël Tanter, Mathieu Pernot, Mathias Fink, Jean Provost
  • Patent number: 9320491
    Abstract: Ultrasound methods, devices, and systems are described which support a useful compromise in terms of spatial resolution and temporal resolution for capturing motion in tissue structures. Tissue engineering articles, methods, systems, and devices which employ ultrasound to deliver biological agents to selected regions of a tissue scaffold, deliver mechanical stimulation to cells growing in a tissue scaffold, and enhance the perfusion of fluids through tissue scaffolds.
    Type: Grant
    Filed: October 18, 2013
    Date of Patent: April 26, 2016
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Elisa E. Konofagou, Jean Provost, Jianwen Luo, Stanley J. Okrasinski, III, Stéphane Thiébaut, Vu Thanh-Hieu Nguyen