Patents by Inventor Jean-Robert Labrosse

Jean-Robert Labrosse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for the preparation of 1-aryl-5-alkyl pyrazole compounds
    Patent number: 9273007
    Abstract: Provided are improved processes for the preparation of 1-aryl pyrazole compounds of formula (I) and (IB): which are substituted at the 5-position of the pyrazole ring with a carbon-linked functional group. The process described are efficient and scalable and do not utilize hazardous sulfenyl halide reagents.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: March 1, 2016
    Assignee: MERIAL, INC.
    Inventors: Charles Q. Meng, Loic Patrick Le Hir de Fallois, Hyoung Ik Lee, Xinxi Zhan, Jean Robert Labrosse, Michel Mulhauser
  • PROCESSES FOR THE PREPARATION OF 1-ARYL-5-ALKYL PYRAZOLE COMPOUNDS
    Publication number: 20150073153
    Abstract: Provided are improved processes for the preparation of 1-aryl pyrazole compounds of formula (I) and (IB): which are substituted at the 5-position of the pyrazole ring with a carbon-linked functional group. The process described are efficient and scalable and do not utilize hazardous sulfenyl halide reagents.
    Type: Application
    Filed: November 17, 2014
    Publication date: March 12, 2015
    Applicant: Merial Limited
    Inventors: Charles Q. Meng, Loic Patrick Le Hir de Fallois, Hyoung Ik Lee, Xinxi Zhan, Jean Robert Labrosse, Michel Mulhauser
  • Processes for the preparation of 1-aryl-5-alkyl pyrazole compounds
    Patent number: 8937185
    Abstract: Provided are improved processes for the preparation of 1-aryl pyrazole compounds of formula (I) and (IB): which are substituted at the 5-position of the pyrazole ring with a carbon-linked functional group. The process described are efficient and scalable and do not utilize hazardous sulfenyl halide reagents.
    Type: Grant
    Filed: April 22, 2013
    Date of Patent: January 20, 2015
    Assignee: Merial Limited
    Inventors: Charles Q Meng, Loic Patrick Le Hir de Fallois, Hyoung Ik Lee, Xinxi Zhan, Jean Robert Labrosse, Michel Mulhauser
  • Pyrimidinone derivatives, preparation thereof and pharmaceutical use thereof
    Patent number: 8815853
    Abstract: The invention relates to novel products of formula (Ia) or (Ib): these products being in all the isomeric forms and salts as drugs, notably as anticancer drugs.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: August 26, 2014
    Assignee: Sanofi
    Inventors: Jerome Arigon, Maurice Brollo, Jacques Clement, Romain Combet, Florence Durand, Youssef El Ahmad, Jean-Robert Labrosse, Jean-Philippe Letallec, Baptiste Ronan
  • PYRIMIDINONE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL USE THEREOF
    Publication number: 20130289031
    Abstract: The invention relates to novel products of formula (Ia) or (Ib): these products being in all the isomeric forms and salts as drugs, notably as anticancer drugs.
    Type: Application
    Filed: December 22, 2011
    Publication date: October 31, 2013
    Applicant: SANOFI
    Inventors: Jerome Arigon, Maurice Brollo, Jacques Clement, Romain Combet, Florence Durand, Youssef El Ahmad, Jean-Robert Labrosse, Jean-Philippe Letallec, Baptiste Ronan
  • PROCESSES FOR THE PREPARATION OF 1-ARYL-5-ALKYL PYRAZOLE COMPOUNDS
    Publication number: 20130281710
    Abstract: Provided are improved processes for the preparation of 1-aryl pyrazole compounds of formula (I) and (IB): which are substituted at the 5-position of the pyrazole ring with a carbon-linked functional group. The process described are efficient and scalable and do not utilize hazardous sulfenyl halide reagents.
    Type: Application
    Filed: April 22, 2013
    Publication date: October 24, 2013
    Applicant: MERIAL LIMITED
    Inventors: Charles Q. Meng, Loic Patrick Le Hir de Fallois, Hyoung Ik Lee, Xinxi Zhan, Jean Robert Labrosse, Michel Mulhauser
  • Pyridopyrimidone derivatives, preparation thereof, therapeutic use thereof
    Patent number: 7842806
    Abstract: The disclosure relates to pyrido[2,3-d]pyrimidone compounds, to the preparation thereof and to the therapeutic use thereof, wherein said compounds are of general formula (I): in the form of a base or of an addition salt with an acid which is pharmaceutically acceptable, in the form of hydrates or of solvates, and also in the form of enantiomers, diastereoisomers and a mixture thereof. The disclosure also relates to processes for preparing said compounds, to pharmaceutical compositions containing a compound of general formula (I), and to the therapeutic use of said compounds and compositions.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: November 30, 2010
    Assignee: sanofi-aventis
    Inventors: Pierre Perreaut, Samir Jegham, Bernard Bourrie, Pierre Casellas, Jean-Robert Labrosse, Florence Durand
  • PYRIDOPYRIMIDONE DERIVATIVES, PREPARATION THEREOF, THERAPEUTIC USE THEREOF
    Publication number: 20090048277
    Abstract: The disclosure relates to pyrido[2,3-d]pyrimidone compounds, to the preparation thereof and to the therapeutic use thereof, wherein said compounds are of general formula (I): in the form of a base or of an addition salt with an acid which is pharmaceutically acceptable, in the form of hydrates or of solvates, and also in the form of enantiomers, diastereoisomers and a mixture thereof. The disclosure also relates to processes for preparing said compounds, to pharmaceutical compositions containing a compound of general formula (I), and to the therapeutic use of said compounds and compositions.
    Type: Application
    Filed: July 2, 2008
    Publication date: February 19, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Pierre PERREAUT, Samir JEGHAM, Bernard BOURRIE, Pierre CASELLAS, Jean-Robert LABROSSE, Florence DURAND