Patents by Inventor Jean-Sébastien Delisle

Jean-Sébastien Delisle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EXPANSION OF NK AND DC CELLS IN VIVO MEDIATING IMMUNE RESPONSE
    Publication number: 20210085714
    Abstract: It is provided a method of expanding dendritic (DC) cells and/or natural killer (NK) cells in vivo in a patient comprising the steps of producing a graft of stem and progenitor cells cultured with UM171 or analogues therefrom and expanded before being administered to the patient. The expansion or increase in dendritic (DC) cells and/or natural killer (NK) cells population in the patient results in an increase immune response reducing transplant related mortality (TRM), severe graft-versus-host disease (GVHD), relapse, and/or severe viral infections.
    Type: Application
    Filed: February 20, 2019
    Publication date: March 25, 2021
    Inventors: Guy SAUVAGEAU, Sandra COHEN, Jean ROY, Silvy LACHANCE, Jean-Sébastien DELISLE, Jalila CHAGRAOUI
  • NOVEL MINOR HISTOCOMPATIBILITY ANTIGENS AND USES THEREOF
    Publication number: 20190359681
    Abstract: Novel minor histocompatibility antigens (MiHAs) are described. These novel MiHAs were selected based on two features: (i) they are encoded by loci with a minor allele frequency (MAF) of at least 0.05; and (ii) they have adequate tissue distribution. Compositions, nucleic acids and cells related to these novel MiHAs are also described. The present application also discloses the use of these novel MiHAs, and related compositions, nucleic acids and cells, in applications related to cancer immunotherapy, for example for the treatment of hematologic cancers such as leukemia.
    Type: Application
    Filed: August 13, 2019
    Publication date: November 28, 2019
    Inventors: Claude Perreault, Diana Paola Granados, Jean-Sébastien Delisle, Pierre Thibault, Sébastien Lemieux
  • Minor histocompatibility antigens and uses thereof
    Patent number: 10414813
    Abstract: Novel minor histocompatibility antigens (MiHAs) are described. These novel MiHAs were selected based on two features: (i) they are encoded by loci with a minor allele frequency (MAF) of at least 0.05; and (ii) they have adequate tissue distribution. Compositions, nucleic acids and cells related to these novel MiHAs are also described. The present application also discloses the use of these novel MiHAs, and related compositions, nucleic acids and cells, in applications related to cancer immunotherapy, for example for the treatment of hematologic cancers such as leukemia.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: September 17, 2019
    Assignees: UNIVERSITÉ DE MONTRÉAL, RSEM, LIMITED PARTNERSHIP
    Inventors: Claude Perreault, Diana Paola Granados, Jean-Sébastien Delisle, Pierre Thibault, Sébastien Lemieux
  • NOVEL MINOR HISTOCOMPATIBILITY ANTIGENS AND USES THEREOF
    Publication number: 20180030112
    Abstract: Novel minor histocompatibility antigens (MiHAs) are described. These novel MiHAs were selected based on two features: (i) they are encoded by loci with a minor allele frequency (MAF) of at least 0.05; and (ii) they have adequate tissue distribution. Compositions, nucleic acids and cells related to these novel MiHAs are also described. The present application also discloses the use of these novel MiHAs, and related compositions, nucleic acids and cells, in applications related to cancer immunotherapy, for example for the treatment of hematologic cancers such as leukemia.
    Type: Application
    Filed: February 9, 2016
    Publication date: February 1, 2018
    Inventors: Claude Perreault, Diana Paola Granados, Jean-Sébastien Delisle, Pierre Thibault, Sébastien Lemieux