Patents by Inventor Jean Sainte-Laudy

Jean Sainte-Laudy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Allergy test based on flow cytometric analysis
    Patent number: 8563258
    Abstract: The invention pertains to a method for the determination of basophil activation induced by a test substance by flow cytometric measurement of the changes of the mean or median fluorescence intensities (MFI) of the basophilic Fc?RI receptor present on the cell surface of basophils (MFI-Fc?RI) and/or the IgE antibodies bound to the Fc?RI receptor (MFI-IgE), and the CD63 antigen exposed on the cell surface of basophils after their activation (MFI-CD63), by means of a mixture of anti-CD63, anti-Fc?RI or anti-IgE, and anti-CCR3 antibodies each labelled with a distinct fluorophore, of which at least one antibody acts as a basophil selection marker and at least two antibodies act as basophil activation markers, and bringing the mean fluorescence intensities of the activation markers in correlation to obtain an Activation Index.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: October 22, 2013
    Assignee: Buhlmann Laboratories AG
    Inventors: Jean Sainte-Laudy, Michael Schneider, Jakob Matthias Weber
  • ALLERGY TEST BASED ON FLOW CYTOMETRIC ANALYSIS
    Publication number: 20100221756
    Abstract: The invention pertains to a method for the determination of basophil activation induced by a test substance by flow cytometric measurement of the changes of the mean or median fluorescence intensities (WI) of the basophilic Fc?RI receptor present on the cell surface of basophils (MFI-Fc?RI) and/or the IgE antibodies bound to the Fc?RI receptor (MFI-IgE), and the CD63 antigen exposed on the cell surface of basophils after their activation (MFI-CD63), by means of a mixture of anti-CD63, anti-Fc?RI or anti-IgE, and anti-CCR3 antibodies each labelled with a distinct fluorophore, of which at least one antibody acts as a basophil selection marker and at least two antibodies act as basophil activation markers, and bringing the mean fluorescence intensities of the activation markers in correlation to obtain an Activation Index.
    Type: Application
    Filed: September 11, 2008
    Publication date: September 2, 2010
    Applicant: BUHLMANN LABORATORIES AG
    Inventors: Jean Sainte-Laudy, Michael Schneider, Jakob Weber