Abstract: The present invention relates to gene promoters whose methylation status correlates with the clinical survival outcome of glioblastoma patients treated according to the Stupp protocol. More specifically, the invention provides methods and kits for the prognosis of survival outcome and/or treatment response in glioblastoma patients.

Abstract: The invention relates to a dispenser device for dispensing components designed for enabling parts to be assembled together. The device comprises: a main storage magazine for storing the components; an extraction plate for extracting components, which plate has an inclined edge that is arranged to come to bear on the components; actuation means for actuating the plate so as to drive it in up-and-down vertical reciprocating motion, and so as to remove the components upwards; and a temporary storage system for temporarily storing the components, which system has an upstream portion arranged to come into register with the edge when the plate is in the high position, and to enable components to be transferred from the plate into said storage system, which system is provided with transfer means arranged to convey the components from the upstream portion towards a downstream portion that is designed to enable the components to be extracted in succession from the device.

Abstract: The invention relates to a process and a device for producing a contour of a planiform piece, intended, in particular, for the internal trim of motor vehicles, in which the piece (1) is cut to define at least an apex (2) of the contour (3), having a given profile P, and a side (4), or so-called first side, of the contour (3) extending from the apex (2). According to the invention, there are carried out sequentially: on one hand, cutting of the piece (1) to produce simultaneously at least the apex (2), according to the profile P, and to cut the first side (4) over a portion, referred to as a fraction F, of its length extending from the apex (2); on the other hand, at least another operation of cutting the piece (1) to produce the first side (4), including at least a portion at least of the fraction F.

Abstract: The invention relates to a process and a device for forming a planiform piece intended, in particular, for the interior fittings of motor vehicles, in which a layer of support material (1) is covered, at least on one of its faces (2) and in the area of a portion (3), at least, of its contour, or so-called portion to be bordered, with a cladding sheet (4) and said support (1) is cut along said portion to be bordered (3) in such a way that said cladding (4) projects from said support (1) in the area of said portion. According to the invention, a cutting tool (5) is pre-positioned between said cladding (4) and said support (1) along said portion to bordered (3) said cutting is effected with said cutting tool (5), when the support (1) is covered by the cladding (4).

Abstract: A decorative component for use as a piece of trim including an unlaminated flexible sheet of material having a front face and a back face and a periphery, and a stiffener for fixing a shape of the sheet of material relative to a desired shape of the decorative component. The stiffener is a flexible bead affixed to at least a portion of only the periphery of only the back base of the sheet of material. The front face of the sheet of material is an aspect conferring face.

Abstract: A decorative component for use as a piece of trim of a vehicle having a sheet of material with a stiffening element affixed thereto. The sheet of material has an aspect conferring face on one face thereof. The stiffening element fixes the shape of the sheet of material relative to a desired shape of the decorative component. The stiffening element is a bead affixed to at least a portion of the periphery of the sheet of material. The bead can be wither continuous or discontinuous along the periphery.

Abstract: A decorative component for use as a piece of trim including an unlaminated flexible sheet of material having a front face and a back face and a periphery, and a stiffener for fixing a shape of the sheet of material relative to a desired shape of the decorative component. The stiffener is a flexible bead affixed to at least a portion of only the periphery of only the back base of the sheet of material. The front face of the sheet of material is an aspect conferring face.

Abstract: The invention relates to a process and a device for producing a contour of a planiform piece, intended, in particular, for the internal trim of motor vehicles, in which said piece (1) is cut to define at least an apex (2) of said contour (3), having a given profile P, and a side (4), or so-called first side, of said contour (3) extending from said apex (2). According to the invention, there are carried out sequentially: on one hand, cutting of said piece (1) to produce simultaneously at least said apex (2), according to said profile P, and to cut said first side (4) over a portion, referred to as a fraction F, of its length extending from said apex (2); on the other hand, at least another operation of cutting said piece (1) to produce said first side (4), including at least a portion at least of said fraction F.

Abstract: The invention relates to a process and a device for forming a planiform piece intended, in particular, for the interior fittings of motor vehicles, in which a layer of support material (1) is covered, at least on one of its faces (2) and in the area of a portion (3), at least, of its contour, or so-called portion to be bordered, with a cladding sheet (4) and said support (1) is cut along said portion to be bordered (3) in such a way that said cladding (4) projects from said support (1) in the area of said portion. According to the invention, a cutting tool (5) is pre-positioned between said cladding (4) and said support (1) along said portion to bordered (3) said cutting is effected with said cutting tool (5), when the support (1) is covered by the cladding (4).

Abstract: A decorative component (1), in particular designed to constitute a piece of internal trim of a vehicle, including at least a sheet of material (2) provided with stiffening means (3) and having, at least locally, on at least one of its faces, referred to as an aspect conferring face (4), an aesthetic and comfortable aspect. According to the method, the stiffening means (3) include a bead (5) of material, whether continuous or discontinuous, provided on a part at least of the periphery of the sheet (2) to fix its shape according to the shape desired for the component. The method also relates to manufacturing such a decorative component and to a use thereof, as well as to a process for manufacturing a piece of internal trim of a vehicle, for example a door panel, using the decorative component.

Abstract: The invention relates first of all to a decorative component (1), in particular designed to constitute a piece of trim or to be integrated in a piece of internal trim of a vehicle, constituted by at least a sheet of material (2), provided with stiffening means (3) and having, at least locally, on at least one of its faces, referred to as an aspect conferring face (4), an aesthetic and/or comfortable aspect.