Patents by Inventor Jean-Yves Francois Dubois

Jean-Yves Francois Dubois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Host cells and methods of producing disulfide bond containing proteins
    Patent number: 8852886
    Abstract: The invention provides for genetically modified Bacillus host cells having decreased cytoplasmic reductase activity, such as decreased TrxA activity, and a nucleic acid encoding a heterologous Staphylococcal oxidase. The invention also provides for methods of producing di-sulfide bond containing proteins using the host cells of the invention and methods of improving protein folding using the host cell of the invention.
    Type: Grant
    Filed: March 24, 2009
    Date of Patent: October 7, 2014
    Assignee: Danisco US Inc.
    Inventors: Jean-Yves Francois Dubois, Roelof Hendrik Matthijs Kouwen, Jan Maarten Van Dijl
  • Host Cells and Methods Of Producing Disulfide Bond Containing Proteins
    Publication number: 20110236926
    Abstract: The invention provides for genetically modified Bacillus host cells having decreased cytoplasmic reductase activity, such as decreased TrxA activity, and a nucleic acid encoding a heterologous Staphylococcal oxidase. The invention also provides for methods of producing di-sulfide bond containing proteins using the host cells of the invention and methods of improving protein folding using the host cell of the invention.
    Type: Application
    Filed: March 24, 2009
    Publication date: September 29, 2011
    Inventors: Jean-Yves Francois Dubois, Roelof Hendrik Matthijs Kouwen, Jan Maarten Van Dijl