Patents by Inventor Jean-Yves Reginster

Jean-Yves Reginster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8329874
    Abstract: Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.
    Type: Grant
    Filed: August 30, 2011
    Date of Patent: December 11, 2012
    Assignee: Université de Liège
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
  • Publication number: 20120010389
    Abstract: Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.
    Type: Application
    Filed: August 30, 2011
    Publication date: January 12, 2012
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
  • Publication number: 20110223684
    Abstract: Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.
    Type: Application
    Filed: January 20, 2011
    Publication date: September 15, 2011
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
  • Patent number: 7915001
    Abstract: Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: March 29, 2011
    Assignee: Universite De Liege
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
  • Patent number: 7728112
    Abstract: A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals utilizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG (SEQ ID NO:1), located in the helical region of collagen type II.
    Type: Grant
    Filed: August 7, 2008
    Date of Patent: June 1, 2010
    Assignee: Universite de Liege
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
  • Publication number: 20090203040
    Abstract: Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.
    Type: Application
    Filed: June 27, 2008
    Publication date: August 13, 2009
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
  • Publication number: 20090042220
    Abstract: A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals utilizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG (SEQ ID NO:1), located in the helical region of collagen type II.
    Type: Application
    Filed: August 7, 2008
    Publication date: February 12, 2009
    Applicant: Universite de Liege
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
  • Patent number: 7410770
    Abstract: A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals utilizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG, located in the helical region of collagen type II.
    Type: Grant
    Filed: March 12, 2003
    Date of Patent: August 12, 2008
    Assignee: Universite De Liege
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
  • Patent number: 7393649
    Abstract: Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.
    Type: Grant
    Filed: March 12, 2003
    Date of Patent: July 1, 2008
    Assignee: Universite de Liege
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
  • Publication number: 20050176081
    Abstract: Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.
    Type: Application
    Filed: March 12, 2003
    Publication date: August 11, 2005
    Inventors: Jean-Yves Reginster, Michelle Deberg, Yves Henrotin
  • Publication number: 20050170429
    Abstract: A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals ultizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG, located in the helical region of collagen type II.
    Type: Application
    Filed: March 12, 2003
    Publication date: August 4, 2005
    Inventors: Jean-Yves Reginster, Michele Deberg, Yves Henrotin, Stephan Christgau