Patents by Inventor Jeanette Fairhurst

Jeanette Fairhurst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-IL36R ANTIBODIES
    Publication number: 20220162326
    Abstract: The present invention provides antibodies and antigen-binding fragments (e.g., human antibodies) that bind specifically to human Interleukin-36 receptor (IL36R). Methods for treating or preventing diseases mediated by IL36R (e.g., skin or colon inflammatory conditions such as palmo-plantar pustular psoriasis, palmoplantar pustulosis, generalized pustular psoriasis, ulcerative colitis or IBD) using the antibodies and fragments are also provided along with methods of making the antibodies and fragments.
    Type: Application
    Filed: February 1, 2022
    Publication date: May 26, 2022
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Jeanette Fairhurst, Elena Garnova, William Olson, Sokol Haxhinasto
  • Anti-IL36R antibodies
    Patent number: 11267893
    Abstract: The present invention provides antibodies and antigen-binding fragments (e.g., human antibodies) that bind specifically to human Interleukin-36 receptor (IL36R). Methods for treating or preventing diseases mediated by IL36R (e.g., skin or colon inflammatory conditions such as palmo-plantar pustular psoriasis, palmoplantar pustulosis, generalized pustular psoriasis, ulcerative colitis or IBD) using the antibodies and fragments are also provided along with methods of making the antibodies and fragments.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: March 8, 2022
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Jeanette Fairhurst, Elena Garnova, William Olson, Sokol Haxhinasto
  • ANTI-IL36R ANTIBODIES
    Publication number: 20200017592
    Abstract: The present invention provides antibodies and antigen-binding fragments (e.g., human E antibodies) that bind specifically to human IL-36 receptor. Methods for treating or preventing diseases mediated by IL36R (e.g., skin or colon inflammatory conditions such as palmo-plantar pustular psoriasis, palmoplantar pustulosis, generalized pustular psoriasis, ulcerative colitis or IBD) using the antibodies and fragments are also provided along with methods of making the antibodies and fragments.
    Type: Application
    Filed: July 16, 2019
    Publication date: January 16, 2020
    Inventors: Jeanette Fairhurst, Elena Garnova, William Olson
  • IL-4/IL-13 specific polypeptides and therapeutic uses thereof
    Patent number: 7410781
    Abstract: Polypeptides and multimeric polypeptides capable of binding interleukin-4 (IL-4) and interluekin-13 (IL-13) which are useful therapeutically in methods of treating IL-4 and IL-13-related conditions or diseases.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: August 12, 2008
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Margaret Karow, Jeanette Fairhurst
  • High affinity antibodies to human IL-6 receptor
    Publication number: 20070280945
    Abstract: A human antibody or an antigen-binding fragment which binds human IL-6 receptor (hIL-6R) with a KD of about 500 pM or less and blocks IL-6 activity with an IC50 of 200 pM or less. In preferred embodiments, the antibody the antibody or antigen-binding fragment binds hIL-6R with an affinity at least 2-fold higher relative to its binding monkey IL-6R.
    Type: Application
    Filed: June 1, 2007
    Publication date: December 6, 2007
    Inventors: Sean Stevens, Tammy Huang, Joel Martin, Jeanette Fairhurst, Ashique Rafique, Eric Smith, Kevin Pobursky, Nicholas Papadopoulos, James Fandl, Gang Chen, Margaret Karow
  • High affinity human antibodies to human IL-18 receptor
    Publication number: 20070237776
    Abstract: An isolated antibody or antibody fragment that binds human interleukin-18 receptor alpha (hIL-18R?), comprising a light chain variable region (LCVR) selected from the group consisting of SEQ ID NO: 5, 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 61, 65, 69, 73, 77, and 81 and/or a heavy chain variable region (HCVR) selected from the group consisting of SEQ ID NO: 3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 63, 67, 71, 75, and 79, or a fragment or sequence modified by an amino acid substitution, deletion or addition thereof.
    Type: Application
    Filed: April 6, 2007
    Publication date: October 11, 2007
    Inventors: Tammy Huang, Sean Stevens, Joel Martin, Jeanette Fairhurst, Kevin Pobursky, Margaret Karow, Joan Windsor, Warren Mikulka
  • IL-4/IL-13 specific polypeptides and therapeutic uses thereof
    Publication number: 20050191730
    Abstract: Polypeptides and multimeric polypeptides capable of binding interleukin-4 (IL-4) and interluekin-13 (IL-13) which are useful therapeutically in methods of treating IL-4 and IL-13-related conditions or diseases.
    Type: Application
    Filed: February 25, 2005
    Publication date: September 1, 2005
    Inventors: Margaret Karow, Jeanette Fairhurst