Patents by Inventor Jeanine D. Mattson

Jeanine D. Mattson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomarkers for TSLP treatment
    Patent number: 9732151
    Abstract: The present invention relates to biomarker responsive to treatment with an anti-Thymic Stromal Lymphopoietin (TSLP) antibody.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: August 15, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Maribel Beaumont, Jeanine D. Mattson, Jennifer R. Louten, Terrill K. McClanahan, Rene de Waal Malefyt
  • BIOMARKERS FOR TSLP TREATMENT
    Publication number: 20140302061
    Abstract: The present invention relates to biomarker responsive to treatment with a TSLP antagonist.
    Type: Application
    Filed: October 31, 2012
    Publication date: October 9, 2014
    Inventors: Maribel Beaumont, Jeanine D. Mattson, Jennifer R. Louten, Terrill K. McClanahan, Rene de Waal Malefyt
  • Canine thymic stromal lymphopoietin protein and uses thereof to treat allergic symptoms
    Patent number: 8791242
    Abstract: The present invention discloses a canine TSLP protein and a nucleic acid that encodes that protein. Peptide fragments of the protein that comprise specific epitopes of the canine TSLP protein are also disclosed. The canine TSLP protein and related peptide fragments may be used as an antigen for immunological assays, as well as for vaccines that induce anti-TSLP antibodies. The present invention further discloses methods of making and using the canine TSLP gene, the canine TSLP protein, and the related peptide fragments.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: July 29, 2014
    Assignee: Intervet Inc.
    Inventors: Jeanine D. Mattson, Daniel M. Gorman, Rene de Waal Malefyt, Mohamad A. Morsey
  • CANINE THYMIC STROMAL LYMPHOPOIETIN PROTEIN AND USES THEREOF
    Publication number: 20130183291
    Abstract: The present invention discloses a canine TSLP protein and a nucleic acid that encodes that protein. Peptide fragments of the protein that comprise specific epitopes of the canine TSLP protein are also disclosed. The canine TSLP protein and related peptide fragments may be used as an antigen for immunological assays, as well as for vaccines that induce anti-TSLP antibodies. The present invention further discloses methods of making and using the canine TSLP gene, the canine TSLP protein, and the related peptide fragments.
    Type: Application
    Filed: November 11, 2011
    Publication date: July 18, 2013
    Inventors: Jeanine D. Mattson, Daniel M. Gorman, Rene de Waal Malefyt, Mohamad A. Morsey
  • BIOMARKERS FOR IDIOPATHIC PULMONARY FIBROSIS
    Publication number: 20130116166
    Abstract: Biomarkers, kits, and diagnostic and treatment methods for idiopathic pulmonary fibrosis are provided.
    Type: Application
    Filed: April 25, 2011
    Publication date: May 9, 2013
    Inventors: Bela Desai, Jeanine D. Mattson, Robert Fick, JR.
  • Nucleic acids encoding TNF?
    Patent number: 8426573
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: April 23, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • MAMMALIAN GENES; RELATED REAGENTS AND METHODS
    Publication number: 20120164147
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Application
    Filed: March 7, 2012
    Publication date: June 28, 2012
    Applicant: SCHERING CORPORATION
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • Nucleic acid encoding TNFx protein
    Patent number: 8148507
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: April 3, 2012
    Assignee: Schering Corporation
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • Fusion proteins comprising canine thymic stromal lymphopoietin protein and uses thereof
    Patent number: 8076456
    Abstract: The present invention discloses a canine TSLP protein and a nucleic acid that encodes that protein. Peptide fragments of the protein that comprise specific epitopes of the canine TSLP protein are also disclosed. The canine TSLP protein and related peptide fragments may be used as an antigen for immunological assays, as well as for vaccines that induce anti-TSLP antibodies. The present invention further discloses methods of making and using the canine TSLP gene, the canine TSLP protein, and the related peptide fragments.
    Type: Grant
    Filed: March 10, 2010
    Date of Patent: December 13, 2011
    Assignee: Intervet Inc.
    Inventors: Jeanine D. Mattson, Daniel M. Gorman, Rene de Waal Malefyt, Mohamad A. Morsey
  • Canine RANKL and methods for preparing and using the same
    Patent number: 8030450
    Abstract: The present invention provides isolated nucleic acid molecules that encode a substantial part of canine RANKL polypeptide, including the extracellular domains of that polypeptide, the polypeptide and fragments thereof. Vectors and host cells encoding and expressing canine RANKL polypeptide are provided, as well as antibodies that bind to RANKL and that inhibit RANKL activity. Also provided are methods of treating an animal to inhibit or treat the loss of bone minerals.
    Type: Grant
    Filed: November 6, 2008
    Date of Patent: October 4, 2011
    Assignee: Intervet Inc.
    Inventors: Jeanine D. Mattson, Terrill McClanahan
  • MAMMALIAN GENES; RELATED REAGENTS AND METHODS
    Publication number: 20110165165
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Application
    Filed: December 21, 2010
    Publication date: July 7, 2011
    Applicant: Schering Corporation
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • CANINE THYMIC STROMAL LYMPHOPOIETIN PROTEIN AND USES THEREOF
    Publication number: 20110033478
    Abstract: The present invention discloses a canine TSLP protein and a nucleic acid that encodes that protein. Peptide fragments of the protein that comprise specific epitopes of the canine TSLP protein are also disclosed. The canine TSLP protein and related peptide fragments may be used as an antigen for immunological assays, as well as for vaccines that induce anti-TSLP antibodies. The present invention further discloses methods of making and using the canine TSLP gene, the canine TSLP protein, and the related peptide fragments.
    Type: Application
    Filed: March 10, 2010
    Publication date: February 10, 2011
    Inventors: JEANINE D. MATTSON, DANIEL M. GORMAN, RENE DE WAAL MALEFYT, MOHAMAD A. MORSEY
  • Canine thymic stromal lymphopoietin protein and uses thereof
    Patent number: 7718772
    Abstract: The present invention discloses a canine TSLP protein and a nucleic acid that encodes that protein. Peptide fragments of the protein that comprise specific epitopes of the canine TSLP protein are also disclosed. The canine TSLP protein and related peptide fragments may be used as an antigen for immunological assays, as well as for vaccines that induce anti-TSLP antibodies. The present invention further discloses methods of making and using the canine TSLP gene, the canine TSLP protein, and the related peptide fragments.
    Type: Grant
    Filed: December 11, 2007
    Date of Patent: May 18, 2010
    Assignee: Schering-Plough Animal Health Corporation
    Inventors: Jeanine D. Mattson, Daniel M. Gorman, Rene de Waal Malefyt, Mohamad A. Morsey
  • MAMMALIAN GENES; RELATED REAGENTS AND METHODS
    Publication number: 20100104576
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Application
    Filed: December 22, 2009
    Publication date: April 29, 2010
    Applicant: SCHERING CORPORATION
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • MAMMALIAN GENES; RELATED REAGENTS AND METHODS
    Publication number: 20090155242
    Abstract: Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
    Type: Application
    Filed: September 22, 2008
    Publication date: June 18, 2009
    Applicant: SCHERING CORPORATION
    Inventors: Christi L. Parham, Daniel M. Gorman, Hirokazu Kurata, Naoko Arai, Theodore R. Sana, Jeanine D. Mattson, Erin E. Murphy, Chetan Savkoor, Jeffery Grein, Kathleen M. Smith, Terrill K. McClanahan
  • CANINE RANKL AND METHODS FOR PREPARING AND USING THE SAME
    Publication number: 20090148456
    Abstract: The present invention provides isolated nucleic acid molecules that encode a substantial part of canine RANKL polypeptide, including the extracellular domains of that polypeptide, the polypeptide and fragments thereof. Vectors and host cells encoding and expressing canine RANKL polypeptide are provided, as well as antibodies that bind to RANKL and that inhibit RANKL activity. Also provided are methods of treating an animal to inhibit or treat the loss of bone minerals.
    Type: Application
    Filed: November 6, 2008
    Publication date: June 11, 2009
    Inventors: Jeanine D. Mattson, Terrill McClanahan
  • MAMMALIAN CELL SURFACE ANTIGENS; RELATED REAGENTS
    Publication number: 20090092597
    Abstract: Purified genes encoding a T cell surface antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this antigen are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Application
    Filed: August 9, 2007
    Publication date: April 9, 2009
    Inventors: DANIEL M. GORMAN, JEANINE D. MATTSON
  • Canine RANKL and methods for preparing and using the same
    Patent number: 7462700
    Abstract: The present invention provides isolated nucleic acid molecules that encode a substantial part of canine RANKL polypeptide, including the extracellular domains of that polypeptide, the polypeptide and fragments thereof. Vectors and host cells encoding and expressing canine RANKL polypeptide are provided, as well as antibodies that bind to RANKL and that inhibit RANKL activity. Also provided are methods of treating an animal to inhibit or treat the loss of bone minerals.
    Type: Grant
    Filed: December 10, 2003
    Date of Patent: December 9, 2008
    Assignee: Schering-Plough Animal Health Corporation
    Inventors: Jeanine D. Mattson, Terrill McClanahan
  • Canine Thymic Stromal Lymphopoietin Protein and Uses Thereof
    Publication number: 20080152620
    Abstract: The present invention discloses a canine TSLP protein and a nucleic acid that encodes that protein. Peptide fragments of the protein that comprise specific epitopes of the canine TSLP protein are also disclosed. The canine TSLP protein and related peptide fragments may be used as an antigen for immunological assays, as well as for vaccines that induce anti-TSLP antibodies. The present invention further discloses methods of making and using the canine TSLP gene, the canine TSLP protein, and the related peptide fragments.
    Type: Application
    Filed: December 11, 2007
    Publication date: June 26, 2008
    Inventors: Jeanine D. Mattson, Daniel M. Gorman, Rene de Waal Malefyt, Mohamad A. Morsey
  • Mammalian cell surface antigens; related reagents
    Patent number: 7063841
    Abstract: Purified genes encoding a T cell surface antigen from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this antigen are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: June 20, 2006
    Assignee: Schering Corporation
    Inventors: Daniel E. Gorman, Jeanine D. Mattson