Patents by Inventor Jeanne A Hardy

Jeanne A Hardy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTRACELLULAR DELIVERY OF THERAPEUTIC PROTEINS DESIGNED TO INVADE AND AUTONOMOUSLY LYSE AND METHODS OF USE THEREOF
    Publication number: 20240115671
    Abstract: Provided herein is a bacterial delivery platform that harnesses mechanisms unique to Salmonella to intracellularly deliver protein-based drugs.
    Type: Application
    Filed: February 9, 2022
    Publication date: April 11, 2024
    Inventors: Neil S. Forbes, Vishnu Raman, Nele Van Dessel, Jeanne A. Hardy
  • FUROXAN-BASED COMPOUNDS AND USES THEREOF
    Publication number: 20230121110
    Abstract: Described herein are compounds of the formula (I), as well as pharmaceutical compositions comprising such compounds, and methods for using such compounds/pharmaceutical compositions for treating neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, Huntington's disease, and multiple sclerosis (MS).
    Type: Application
    Filed: October 24, 2022
    Publication date: April 20, 2023
    Inventors: Jeanne A. Hardy, Penchala Narasimharao Meka
  • Furoxan-based compounds and uses thereof
    Patent number: 11512094
    Abstract: Described herein are compounds of the formula (I), as well as pharmaceutical compositions comprising such compounds, and methods for using such compounds/pharmaceutical compositions for treating neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, Huntington's disease, and multiple sclerosis (MS).
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: November 29, 2022
    Assignee: University of Massachusetts
    Inventors: Jeanne A. Hardy, Penchala Narasimharao Meka
  • FUROXAN-BASED COMPOUNDS AND USES THEREOF
    Publication number: 20200339596
    Abstract: Described herein are compounds of the formula (I), as well as pharmaceutical compositions comprising such compounds, and methods for using such compounds/pharmaceutical compositions for treating neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, Huntington's disease, and multiple sclerosis (MS).
    Type: Application
    Filed: January 11, 2019
    Publication date: October 29, 2020
    Inventors: Jeanne A. Hardy, Penchala Narasimharao Meka
  • POLYMERS AND POLYMERIC ASSEMBLIES FOR PEPTIDE AND PROTEIN ENCAOSULATION AND RELEASE, AND METHODS THEREOF
    Publication number: 20180140710
    Abstract: The invention provides polymers and polymeric nanogels that stably encapsulate peptides and proteins, which are controllably released upon degradable of the nano-structures in response to specific microenvironment, and compositions and methods of preparation and use thereof.
    Type: Application
    Filed: May 3, 2016
    Publication date: May 24, 2018
    Inventors: Sankaran Thayumanavan, Jeanne A Hardy
  • Methods for identifying allosteric sites
    Publication number: 20040014140
    Abstract: The present invention relates to exosites and methods for identifying exosites in protein targets. The present invention also relates to methods for identifying allosteric sites and identifying compounds that bind therein.
    Type: Application
    Filed: April 8, 2003
    Publication date: January 22, 2004
    Inventors: Daniel A. Erlanson, Stig K. Hansen, Jeanne Hardy, Joni Lam, Thomas O'Brien