Patents by Inventor Jeanne Leszczynski

Jeanne Leszczynski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process of screening plasma samples for effective antibody titers against respiratory viruses
    Patent number: 5582827
    Abstract: A process for identifying plasma samples containing effective antibody titers for the treatment and/or prophylaxis of infections caused by a respiratory virus. The process comprises contacting a plasma sample containing antibodies against a respiratory virus with the respiratory virus. The mixture of plasma sample and virus is then contacted with a plurality of cells. The remaining non-neutralized virus in the sample is then determined through an immunoassay following replication of the virus in the cells. Plasma samples which, at a preselected minimum antibody titer value, prevent viral replication in the cells, are then selected. Plasma from which the selected samples were derived are then pooled to provide an immunoglobulin preparation having increased effectiveness in the prophylaxis and/or treatment of infections caused by the respiratory virus.
    Type: Grant
    Filed: January 27, 1995
    Date of Patent: December 10, 1996
    Assignee: Massachusetts Health Research Institute, Inc.
    Inventors: George R. Siber, Jeanne Leszczynski
  • Effective antibody titers against respiratory viruses
    Patent number: 5412077
    Abstract: A process for identifying plasma samples containing effective antibody titers for the treatment and/or prophylaxis of infections caused by a respiratory virus. The process comprises contacting a plasma sample containing antibodies against a respiratory virus with the respiratory virus. The mixture of plasma sample and virus is then contacted with a plurality of cells. The remaining non-neutralized virus in the sample is then determined through an immunoassay following replication of the virus in the cells. Plasma samples which, at a preselected minimum antibody titer value, prevent viral replication in the cells, are then selected. Plasma from which the selected samples were derived are then pooled to provide an immunoglobulin preparation having increased effectiveness in the prophylaxis and/or treatment of infections caused by the respiratory virus.
    Type: Grant
    Filed: August 4, 1993
    Date of Patent: May 2, 1995
    Assignee: Massachusetts Health Research Institute, Inc.
    Inventors: George R. Siber, Jeanne Leszczynski