Abstract: Systems and methods for controlling fluid flow are described. In some aspects, a system may include a first port, a second port, and a third port. The system may be configured to be in a first state if a male fitting of a device is not inserted in a female fitting of the third port. The valve may block a first fluid path defined between the first port and the third port if the system is in the first state. The system may also be configured to be in a second state if a male fitting of a device is fully inserted in the female fitting of the third port. The valve may block a second fluid path defined between the first port and the second port if the system is in the second state.

Abstract: Systems and methods for directing fluid flow are described. In some embodiments, a system may include a first port, a second port, and a third port. The system may have a first state in which a male fitting of a device is not inserted in a female fitting of the third port. A valve assembly may block a first fluid path defined between the first port and the third port when the system is in the first state. The system may also have a second state in which the male fitting of the device is fully inserted in the female fitting of the third port. The valve assembly may block a second fluid path defined between the first port and the second port when the system is in the second state.

Abstract: Systems and methods for directing fluid flow are described. In some embodiments, a system may include a first port, a second port, and a third port. The system may have a first state in which a male fitting of a device is not inserted in a female fitting of the third port. The valve assembly may block a first fluid path defined between the first port and the third port when the system is in the first state. The system may also have a second state in which a male fitting of a device is fully inserted in the female fitting of the third port. The valve assembly may block a second fluid path defined between the first port and the second port when the system is in the second state.

Abstract: Fluorescent compositions with enhanced fluorescent intensity are provided. Methods for using the fluorescent compositions in medical imaging are also provided. The enhanced fluorescent compositions can be a mixture or solution comprising a fluorescent dye and a light-scattering emulsion or fluorescence-enhancing diluent. The fluorescent dye, e.g., indocyanine green (ICG), is activated by near-infrared radiation. The fluorescence-enhancing diluent can be milk, infant formula, intravenous fat emulsions, soy bean oil, egg phospholipids, Intralipid, Liposyn, Nutralipid, Soyacal, Travamulsion, SMOFlipid, Clinoleic, Lipovenoes and/or combinations thereof. The fluorescent intensity of the enhanced fluorescent composition can be 5 to 20 or more times greater than that of the fluorescent dye in solution without added fluorescence-enhancing diluent.