Abstract: Microorganisms comprising a maltose-inducible promoter and methods of use in producing biologics and introducing biologics to sites in a maltose-dependent manner. The microorganisms include a maltose-inducible promoter operably connected to a coding sequence of a biologic. The biologic may be a polypeptide or a nucleic acid. Polypeptide biologics may include lytic proteins and/or secreted proteins. Nucleic acid biologics may include antisense RNA, other types of RNA, or other types of nucleic acids. The microorganisms can be used to produce the biologics and/or introduce the biologics to in vitro or in vivo sites in a maltose-dependent manner. The microorganisms can also be used in maltose-dependent gene silencing.

Abstract: Microorganisms comprising a maltose-inducible promoter and methods of use in producing biologics and introducing biologics to sites in a maltose-dependent manner. The microorganisms include a maltose-inducible promoter operably connected to a coding sequence of a biologic. The biologic may be a polypeptide or a nucleic acid. Polypeptide biologics may include lytic proteins and/or secreted proteins. Nucleic acid biologics may include antisense RNA, other types of RNA, or other types of nucleic acids. The microorganisms can be used to produce the biologics and/or introduce the biologics to in vitro or in vivo sites in a maltose-dependent manner. The microorganisms can also be used in maltose-dependent gene silencing.

Abstract: Methods and microorganisms for systemically introducing a polypeptide in the bloodstream of a subject. The methods of the invention include administering into the gastrointestinal tract of a subject a bacterium configured to express and produce and release the polypeptide. The bacterium is administered in an amount effective to introduce the polypeptide in the bloodstream of the subject, preferably in a detectable amount. The microorganisms of the invention include lactic acid bacteria, such as Lactobacillus reuteri, that comprise a recombinant gene configured to express a polypeptide to be systemically introduced.

Abstract: Microorganisms comprising a maltose-inducible promoter and methods of use in producing biologics and introducing biologics to sites in a maltose-dependent manner. The microorganisms include a maltose-inducible promoter operably connected to a coding sequence of a biologic. The biologic may be a polypeptide or a nucleic acid. Polypeptide biologics may include lytic proteins and/or secreted proteins. Nucleic acid biologics may include antisense RNA, other types of RNA, or other types of nucleic acids. The microorganisms can be used to produce the biologics and/or introduce the biologics to in vitro or in vivo sites in a maltose-dependent manner. The microorganisms can also be used in maltose-dependent gene silencing.

Abstract: Disclosed herein is an organic light-emitting display (OLED) device that includes: a substrate having an active area and an inactive area surrounding the active area; a first planarization layer flattening a surface on circuit elements in the active area and inactive area; an organic light-emitting element on the first planarization layer; an encapsulation element on the organic light-emitting element and the first planarization layer, the encapsulation element having a first inorganic layer, a second inorganic layer and an organic layer between the first and second inorganic layers; and a structure in the inactive area and spaced apart from the first planarization layer. The structure includes a first layer made of a same material as the first planarization layer; a plurality of walls on the first layer and spaced apart from each other; and a second layer that fills a space between the plurality of walls.

Abstract: Methods and microorganisms for systemically introducing a polypeptide in the bloodstream of a subject. The methods of the invention include administering into the gastrointestinal tract of a subject a bacterium configured to express and produce and release the polypeptide. The bacterium is administered in an amount effective to introduce the polypeptide in the bloodstream of the subject, preferably in a detectable amount. The microorganisms of the invention include lactic acid bacteria, such as Lactobacillus reuteri, that comprise a recombinant gene configured to express a polypeptide to be systemically introduced.

Abstract: Disclosed herein is an organic light-emitting display (OLED) device that includes: a substrate having an active area and an inactive area surrounding the active area; a first planarization layer flattening a surface on circuit elements in the active area and inactive area; an organic light-emitting element on the first planarization layer; an encapsulation element on the organic light-emitting element and the first planarization layer, the encapsulation element having a first inorganic layer, a second inorganic layer and an organic layer between the first and second inorganic layers; and a structure in the inactive area and spaced apart from the first planarization layer. The structure includes a first layer made of a same material as the first planarization layer; a plurality of walls on the first layer and spaced apart from each other; and a second layer that fills a space between the plurality of walls.

Abstract: A display device includes: a display panel for displaying an image toward a plurality of viewing zones; a light guide plate under the display panel; a lens array disposed along a side of the light guide plate, the lens array including a plurality of lenses; a light source part including a plurality of line light sources each emitting a ray toward the lens array; a position sensing unit for obtaining a position information about the plurality of viewing zones; and a control unit for controlling the display panel, the light source part and the position sensing unit according to the position information.

Abstract: A display device includes: a display panel for displaying an image toward a plurality of viewing zones; a light guide plate under the display panel; a lens array disposed along a side of the light guide plate, the lens array including a plurality of lenses; a light source part including a plurality of line light sources each emitting a ray toward the lens array; a position sensing unit for obtaining a position information about the plurality of viewing zones; and a control unit for controlling the display panel, the light source part and the position sensing unit according to the position information.