Patents by Inventor Jee Won MOK

Jee Won MOK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD AND SYSTEM FOR CULTURING CORNEAL STEM CELL-LIKE CELL LINE BY INDUCING DIFFERENTIATION OF INDUCED PLURIPOTENT STEM CELL USING PROTEIN LIGAND
    Publication number: 20190177690
    Abstract: The present invention relates to a method for culturing corneal stem cell-like cell lines by inducing differentiation of induced pluripotent stem cells (iPSC). The method comprises the following steps: preparing a basal medium comprising DMEM F12, L-ascorbic acid, sodium selenite, and sodium chloride; adding additives for culturing induced pluripotent stem cells to the basal medium; preparing a feeder free culture medium by coating the basal medium with Vitronectin recombinant human protein; adding induced pluripotent stem cells to the feeder free culture medium and culturing them; adding additives for creating an environment for stem cell growth to the feeder free culture medium; adding BMP4 and Wnt3a sequentially to the feeder free culture medium in order to induce differentiation of the induced pluripotent stem cells into corneal stem cell-like cell lines; and culturing the cells differentiated from the induced pluripotent stem cells in PI culture fluid.
    Type: Application
    Filed: August 4, 2017
    Publication date: June 13, 2019
    Inventors: Choun Ki JOO, Jee Won MOK, Hee Jung JU, Jun Sub CHOI