Patents by Inventor Jee Youn Lee

Jee Youn Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250027041
    Abstract: The present invention relates to a composition for inducing direct conversion through oligomerization of CtBPs, and uses of stem cells treated therewith. Since the compounds of the present invention can induce transdifferentiation of adult stem cells into neural progenitor cells by regulating the oligomerization of CtBPs, the compounds can be used for inducing oligomerization of CtBPs or direct conversion. In addition, since ciNSC5 derived from direct conversion exhibits remarkable therapeutic effects in an ALS mouse model, an MS mouse model, a PD rat model, and a chronic spinal cord injury rat model, ciNSC5 can be used as a cellular therapeutic agent.
    Type: Application
    Filed: November 21, 2022
    Publication date: January 23, 2025
    Applicant: YJ CERAPEUTICS INC.
    Inventors: Tae Young YUNE, Jee Youn LEE
  • Patent number: 12202889
    Abstract: The present disclosure provides antibodies that specifically bind to human FAM19A5 and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human FAM19A5 and modulate FAM19A5 activity, e.g., inhibit, suppress, reduce, or reverse the onset of reactive gliosis and/or excessive proliferation of reactive astrocytes, utilizing such antibodies. The present disclosure also provides methods for treating disorders, such as central nervous system damage, a degenerative brain disorder, or a neuropathic pain, by administering an antibody that specifically binds to human FAM19A5.
    Type: Grant
    Filed: April 18, 2022
    Date of Patent: January 21, 2025
    Assignee: NEURACLE SCIENCE CO., LTD.
    Inventors: Bongcheol Kim, Jae Young Seong, Jong Ik Hwang, Eun Bee Cho, Junho Chung, Junyeong Jin, Tae Young Yune, Jee Youn Lee
  • Publication number: 20250017489
    Abstract: A method for counting coughs is provided. The method includes determining a plurality of time points in the sound signal, extracting a plurality of cropped signals from the sound signal by cropping portions of the sound signal, wherein each of the cropped portions corresponds to a signal with a predetermined time length from each of the determined time points in the sound signal, transforming each of the plurality of cropped signals into a spectrogram image, thereby forming a plurality of spectrogram images, determining whether each of the plurality of spectrogram images represents a cough by inputting each of the plurality of spectrogram images into a cough determination model, wherein the cough determination model is a classification model trained to classify the inputted spectrogram image into a cough or non-cough, determining a plurality of tags according to results determined by the cough determination model.
    Type: Application
    Filed: October 2, 2024
    Publication date: January 16, 2025
    Applicant: Soundable Health Korea, Inc.
    Inventors: Jee Young SONG, Ji Young JUNG, Sang Youn KANG, Kyeong Yeon DOO, On Sub KIM, Ah Ra LEE
  • Publication number: 20250023060
    Abstract: An electrode catalyst is configured such that non-noble metal particles, noble metal particles or nitride-doped noble metal particles are supported on a carbon support, wherein the carbon support has a 2D planar crystal structure or a 3D polyhedral crystal structure and is doped with nitrogen, thereby exhibiting increased catalytic activity.
    Type: Application
    Filed: September 20, 2024
    Publication date: January 16, 2025
    Applicants: HYUNDAI MOTOR COMPANY, Kia Corporation, Daegu Gyeongbuk Institute of Science and Technology
    Inventors: Eun Jik Lee, Jee Youn Hwang, Ji Hoon Jang, Ha Young Lee, Jong Sung Yu
  • Publication number: 20220401492
    Abstract: The present invention relates to a composition for treating a spinal cord injury and provides a composition for treating a spinal cord injury comprising, as an active ingredient, stem cells treated with a particular compound and then cultured.
    Type: Application
    Filed: November 18, 2019
    Publication date: December 22, 2022
    Applicant: YJ CERAPEUTICS INC.
    Inventors: Tae Young YUNE, Hea Young PARK, Jee Youn LEE, Sang Ryong JEON, Bong Gun JU
  • Publication number: 20220372122
    Abstract: The present disclosure provides antibodies that specifically bind to human FAM19A5 and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human FAM19A5 and modulate FAM19A5 activity, e.g., inhibit, suppress, reduce, or reverse the onset of reactive gliosis and/or excessive proliferation of reactive astrocytes, utilizing such antibodies. The present disclosure also provides methods for treating disorders, such as central nervous system damage, a degenerative brain disorder, or a neuropathic pain, by administering an antibody that specifically binds to human FAM19A5.
    Type: Application
    Filed: April 18, 2022
    Publication date: November 24, 2022
    Applicant: NEURACLE SCIENCE CO., LTD.
    Inventors: Bongcheol KIM, Jae Young SEONG, Jong Ik HWANG, Eun Bee CHO, Junho CHUNG, Junyeong JIN, Tae Young YUNE, Jee Youn LEE
  • Patent number: 11332521
    Abstract: The present disclosure provides antibodies that specifically bind to human FAM19A5 and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human FAM19A5 and modulate FAM19A5 activity, e.g., inhibit, suppress, reduce, or reverse the onset of reactive gliosis and/or excessive proliferation of reactive astrocytes, utilizing such antibodies. The present disclosure also provides methods for treating disorders, such as central nervous system damage, a degenerative brain disorder, or a neuropathic pain, by administering an antibody that specifically binds to human FAM19A5.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: May 17, 2022
    Assignee: Neuracle Science Co., Ltd.
    Inventors: Bongcheol Kim, Jae Young Seong, Jong Ik Hwang, Eun Bee Cho, Junho Chung, Junyeong Jin, Tae Young Yune, Jee Youn Lee
  • Publication number: 20200316020
    Abstract: The present invention relates to a pharmaceutical composition for the prevention and treatment of blood-brain barrier disorder and central nervous system diseases containing fluoxetine and vitamin C as active ingredients.
    Type: Application
    Filed: June 19, 2020
    Publication date: October 8, 2020
    Applicant: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Tae Young Yune, Hyung-Hwan Baik, Jee Youn Lee, Sam Kim
  • Patent number: 10772866
    Abstract: The present invention relates to a pharmaceutical composition for the prevention and treatment of blood-brain barrier disorder and central nervous system diseases containing fluoxetine and vitamin C as active ingredients.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: September 15, 2020
    Assignee: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Tae Young Yune, Hyung-Hwan Baik, Jee Youn Lee, Sam Kim
  • Publication number: 20190300599
    Abstract: The present disclosure provides antibodies that specifically bind to human FAM19A5 and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human FAM19A5 and modulate FAM19A5 activity, e.g., inhibit, suppress, reduce, or reverse the onset of reactive gliosis and/or excessive proliferation of reactive astrocytes, utilizing such antibodies. The present disclosure also provides methods for treating disorders, such as central nervous system damage, a degenerative brain disorder, or a neuropathic pain, by administering an antibody that specifically binds to human FAM19A5.
    Type: Application
    Filed: November 7, 2017
    Publication date: October 3, 2019
    Applicant: NEURACLE SCIENCE CO., LTD.
    Inventors: Bongcheol KIM, Jae Young SEONG, Jong Ik HWANG, Eun Bee CHO, Junho CHUNG, Junyeong JIN, Tae Young YUNE, Jee Youn LEE
  • Publication number: 20160317492
    Abstract: The present invention relates to a pharmaceutical composition for the prevention and treatment of blood-brain barrier disorder and central nervous system diseases containing fluoxetine and vitamin C as active ingredients.
    Type: Application
    Filed: April 28, 2016
    Publication date: November 3, 2016
    Applicant: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Tae Young Yune, Hyung-Hwan Baik, Jee Youn Lee, Sam Kim
  • Publication number: 20140303256
    Abstract: The present invention relates to a pharmaceutical composition for the prevention and treatment of blood-brain barrier disorder comprising fluoxetine as an active ingredient. More particularly, fluoxetine inhibits the expressions of matrix metalloproteinase(MMP)-2, MMP-9, and MMP-12, which are reported to be related to blood-brain barrier (BBB) disruption and inflammatory reaction after spinal cord injury, specifically inhibits the activations of MMP-2 and MMP-9, inhibits the decomposition of ZO-1, the most representative tight junction protein, so as to maintain tight junction between endothelial cells and to protect blood-brain barrier thereby, inhibits the increase of blood-brain barrier permeability, and inhibits the expressions of chemoattractants of blood cells, such as CXCL-1, CXCL-2, CCL-2, CCL-3 and CCL-4 so as to reduce inflow of blood into spinal cord and recover exercise function which has been deteriorated by spinal cord injury.
    Type: Application
    Filed: October 19, 2012
    Publication date: October 9, 2014
    Applicant: UNIVERSITY INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
    Inventors: Tae Young Yune, Tae Hwan Oh, Hyung Hwan Baik, Jee Youn Lee
  • Patent number: D846100
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: April 16, 2019
    Assignee: COWAY CO., LTD.
    Inventors: Young jo Kim, Sang Hwa Lee, Jee Youn Lee
  • Patent number: D900960
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: November 3, 2020
    Assignee: Coway Co., Ltd.
    Inventors: Jee Youn Lee, Young Jo Kim