Abstract: The present invention relates to a biomarker for predicting responsiveness to an anticancer agent and a use thereof, and more particularly, to: a marker composition for predicting responsiveness to atezolizumab, avelumab, or durvalumab, the marker composition comprising at least one gene selected from the group consisting of armadillo repeat-containing X-linked protein 1 (ARMCX1), serine/threonine-protein kinase D1 (PRKD1), and tyrosine kinase 2 (TYK2), or protein(s) encoded by the at least one gene; a composition for predicting responsiveness; a kit comprising the composition; and a method for providing information for predicting responsiveness. Gene markers according to the present invention are analyzed using patient-derived formalin-fixed paraffin-embedded tissues, and thus do not require the separate collection of samples, and the therefore convenient to analyze.

Abstract: A method of providing tooth-brushing guide information according to an embodiment of the present invention includes an operation in which a user terminal analyzes a captured image of a user, recognizes the face of the user, and identifies landmarks of the face; an operation in which the user terminal generates a personalized dental model of the user using the landmarks, an operation in which the user terminal provides a virtual dental image by augmented reality using the dental model; and an operation in which the user terminal provides tooth-brushing guide information using the dental model.

Abstract: Provided is a method for automatically performing image alignment without a user input. An image alignment method performed by an image alignment device, according to one embodiment of the present invention, can comprise the steps of: recognizing at least one person in an inputted image; determining a person-of-interest among the recognized persons; and performing image alignment, on the basis of the person-of-interest, on the inputted image, wherein the image alignment is performed without an input of a user of the image alignment deice for the image alignment.

Abstract: Provided is a method for automatically performing image alignment without a user input. An image alignment method performed by an image alignment device, according to one embodiment of the present invention, can comprise the steps of: recognizing at least one person in an inputted image; determining a person-of-interest among the recognized persons; and performing image alignment, on the basis of the person-of-interest, on the inputted image, wherein the image alignment is performed without an input of a user of the image alignment device for the image alignment.

Abstract: The present disclosure describes a biomarker for predicting a response to an anticancer agent for immunotherapy, and more particularly, to a marker composition for predicting a response to a programmed cell death protein 1 (PD-1) inhibitor, pembrolizumab, which includes one or more genes selected from the group consisting of armadillo repeat-containing X-linked protein 1 (ARMCX1; NCBI accession number: NM_016608), serine/threonine-protein kinase D1 (PRKD1; NCBI accession number: NM_002742) and tyrosine kinase 2 (TYK2; NCBI accession number: NM_003331) or a protein encoded by the gene, and a composition, kit and information providing method for predicting a response to an anticancer agent. Since the gene marker according to the present disclosure utilizes a formalin-fixed paraffin-embedded tissue derived from a patient for analysis, separate sampling is not needed, and thus analysis is convenient.

Abstract: An embodiment provides a semiconductor device comprising: a substrate; a bonding layer disposed on the substrate; an electrode layer disposed on the bonding layer; a semiconductor structure disposed on the electrode layer and including a first conductive semiconductor layer, a second conductive semiconductor layer, and an active layer disposed between the first conductive semiconductor layer and the second conductive semiconductor layer; a first electrode electrically connected to the first conductive semiconductor layer; and a second electrode electrically connected to the second conductive semiconductor layer, wherein the second conductive semiconductor layer includes a through-hole, and the second electrode is disposed in the through-hole so as to be electrically connected to the electrode layer.

Abstract: A method of providing tooth-brushing guide information according to an embodiment of the present invention includes an operation in which a user terminal analyzes a captured image of a user, recognizes the face of the user, and identifies landmarks of the face; an operation in which the user terminal generates a personalized dental model of the user using the landmarks, an operation in which the user terminal provides a virtual dental image by augmented reality using the dental model; and an operation in which the user terminal provides tooth-brushing guide information using the dental model.

Abstract: Provided is a method for automatically performing image alignment without a user input. An image alignment method performed by an image alignment device, according to one embodiment of the present invention, can comprise the steps of: recognizing at least one person in an inputted image; determining a person-of-interest among the recognized persons; and performing image alignment, on the basis of the person-of-interest, on the inputted image, wherein the image alignment is performed without an input of a user of the image alignment device for the image alignment.

Abstract: A smart toothbrush is provided. The smart toothbrush includes a toothbrush head configured to be provided with bristles, a toothbrush body configured to be connected to the toothbrush head and to be able to be held, a temperature sensor configured to measure a temperature within an oral cavity of a user while the user is brushing teeth using the smart toothbrush, and a processor configured to determine a tooth brushing section in which the user is brushing teeth within the oral cavity, based on a temperature value measured by the temperature sensor.

Abstract: Provided is a GaN light-emitting diode (LED) device. The LED device may include a substrate, an n-type GaN layer on the substrate, an active layer on the n-type GaN layer, a p-type GaN layer on the active layer, a current spreading layer including a transparent conductive metal oxide material on the p-type GaN layer, a plurality of upper current injection electrodes provided on the current spreading layer to be spaced apart from each other, an upper electrode pattern extending to cover the upper current injection electrodes, and an upper electrode pad electrically connected to the upper electrode pattern. The upper electrode pattern may include first and second upper electrode patterns, which are sequentially stacked and are a silver or silver alloy thin layer and a transparent conductive metal oxide thin layer, respectively.

Abstract: A smart toothbrush is provided. The smart toothbrush includes a toothbrush head configured to be provided with bristles, a toothbrush body configured to be connected to the toothbrush head and to be able to be held, a temperature sensor configured to measure a temperature within an oral cavity of a user while the user is brushing teeth using the smart toothbrush, and a processor configured to determine a tooth brushing section in which the user is brushing teeth within the oral cavity, based on a temperature value measured by the temperature sensor.

Abstract: Provided is a GaN light-emitting diode (LED) device. The LED device may include a substrate, an n-type GaN layer on the substrate, an active layer on the n-type GaN layer, a p-type GaN layer on the active layer, a current spreading layer including a transparent conductive metal oxide material on the p-type GaN layer, a plurality of upper current injection electrodes provided on the current spreading layer to be spaced apart from each other, an upper electrode pattern extending to cover the upper current injection electrodes, and an upper electrode pad electrically connected to the upper electrode pattern. The upper electrode pattern may include first and second upper electrode patterns, which are sequentially stacked and are a silver or silver alloy thin layer and a transparent conductive metal oxide thin layer, respectively.

Abstract: The present invention relates to a marker for predicting a gastric cancer prognosis, a composition and a kit for predicting gastric cancer prognosis comprising an agent for measuring the expression level thereof, and a method for predicting gastric cancer prognosis using the marker. According to the present invention, gastric cancer prognosis may be predicted promptly and accurately, and an appropriate treatment plan can be determined based on the predicted prognosis, which has an advantage of contributing to significant reduction of death caused by gastric cancer. Particularly, according to the present invention, the survival rate can be remarkably increased by using the treatment method for a stage III gastric cancer patient to a patient who has been predicted to have a negative prognosis among stage Ib/II gastric cancer patients.

Abstract: The present invention relates to a marker for predicting a gastric cancer prognosis, a composition and a kit for predicting gastric cancer prognosis comprising an agent for measuring the expression level thereof, and a method for predicting gastric cancer prognosis using the marker. According to the present invention, gastric cancer prognosis may be predicted promptly and accurately, and an appropriate treatment plan can be determined based on the predicted prognosis, which has an advantage of contributing to significant reduction of death caused by gastric cancer. Particularly, according to the present invention, the survival rate can be remarkably increased by using the treatment method for a stage III gastric cancer patient to a patient who has been predicted to have a negative prognosis among stage Ib/II gastric cancer patients.