Patents by Inventor Jeevan Ghosalkar

Jeevan Ghosalkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12090163
    Abstract: The invention relates to pharmaceutical compositions comprising ((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)oxy)methyl pivalate or a pharmaceutically acceptable derivative thereof, optionally with an additional agent, methods of making them, and their use in medicine.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: September 17, 2024
    Assignee: CIPLA LIMITED
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar, Atul Daroi, Siddharth Agrawal
  • Publication number: 20240016814
    Abstract: Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include administering to a patient in need thereof an effective amount of desipramine or a salt thereof. The compositions include an effective amount of desipramine or a salt thereof, in some instances combined with one or more additional agents for the treatment of pulmonary hypertension.
    Type: Application
    Filed: April 17, 2023
    Publication date: January 18, 2024
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Publication number: 20240009214
    Abstract: The present invention relates to methods of treatment of infections caused by coronaviridae virus (including COV-ID-19) using ((((((R)-1-(6-amino-9h-purin-9-yl) propan-2-yl) oxy) methyl) (phenoxy) phosphoryl)oxy)methyl pivalate, its derivatives or metabolites thereof. The methods of the present invention can be used in patients with infections caused by coronaviridae virus (including COVID-19) administering ((((((R)-1-(6-amino-9h-purin-9-yl) propan-2-yl) oxy) methyl) (phenoxy) phosphoryl)oxy)methyl pivalate, its derivatives or metabolites in combination with one or more anti-viral drugs.
    Type: Application
    Filed: December 1, 2021
    Publication date: January 11, 2024
    Inventors: Kalpana JOSHI, Jeevan GHOSALKAR, Deepak GAIKWAD
  • Patent number: 11612612
    Abstract: An oral or injectable pharmaceutical composition is provided for treating diseases caused by retroviruses or hepatitis B viruses. The composition comprises a therapeutically effective amount of at least one anti-retroviral drug and a therapeutically effective amount of at least one pharmacokinetic booster or enhancer or derivative thereof. Methods and kits are also provided.
    Type: Grant
    Filed: October 15, 2020
    Date of Patent: March 28, 2023
    Assignee: CIPLA LIMITED
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar, Preeti Raut
  • Publication number: 20230030113
    Abstract: Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include administering to a patient in need thereof an effective amount of Quetiapine or derivative thereof. The compositions include an effective amount of Quetiapine or derivative thereof, in some instances combined with one or more additional agents for the treatment of pulmonary hypertension.
    Type: Application
    Filed: September 22, 2022
    Publication date: February 2, 2023
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Patent number: 11478483
    Abstract: Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include administering to a patient in need thereof an effective amount of Quetiapine or derivative thereof. The compositions include an effective amount of Quetiapine or derivative thereof, in some instances combined with one or more additional agents for the treatment of pulmonary hypertension.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: October 25, 2022
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Publication number: 20220193043
    Abstract: The present invention relates to method of increasing the bioavailability/bio-efficacy of tizanidine by co-administering with resveratrol and bioenhancer. The formulation comprising tizanidine, resvetarol and bioenhancer are also provided which can be used for treatment of muscle spasticity.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 23, 2022
    Inventors: Kalpana JOSHI, Jeevan GHOSALKAR, Deepak Dnyaneshwar GAIKWAD
  • Patent number: 11224591
    Abstract: A pharmaceutical composition is provided for the treatment of systemic infections as well as colonic diseases. The composition comprises a therapeutically effective amount of rifaximin and a therapeutically effective amount of at least one alkaloid or derivative thereof. Methods and kits are also provided.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: January 18, 2022
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Publication number: 20210401851
    Abstract: Disclosed herein are methods of treating cancers by administration of a PAR-4 agonist.
    Type: Application
    Filed: September 9, 2021
    Publication date: December 30, 2021
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Publication number: 20210299098
    Abstract: Disclosed is a method for treating of cancer, specifically pancreatic cancer by administering a selective estrogen receptor modulator (SERM), e.g., levormeloxifene, alone or in combination with one or more additional cancer therapies.
    Type: Application
    Filed: March 30, 2021
    Publication date: September 30, 2021
    Inventors: Kalpana JOSHI, Jeevan GHOSALKAR, Vinay SONAWANE
  • Patent number: 11129836
    Abstract: Disclosed herein are methods of treating cancers by administration of a PAR-4 agonist.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: September 28, 2021
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Patent number: 11040041
    Abstract: The present invention is concerned with the treatment of Pulmonary Arterial Hypertension (PAH) by administering Paliperidone. The instant invention further relates to use of a pharmaceutical composition comprising Paliperidone, for the treatment of PAH.
    Type: Grant
    Filed: January 22, 2020
    Date of Patent: June 22, 2021
    Assignee: Cipla (UK) Limited
    Inventors: Karl Roberts, Geena Malhotra, Dhiraj Abhyankar, Kalpana Joshi, Jeevan Ghosalkar
  • Publication number: 20210100786
    Abstract: A pharmaceutical formulation is provided comprising combination of anti-tuberculosis drug drugs optionally in combination of bioenhancers. The formulation is used for the treatment of diseases caused by mycobacterium tuberculosis. The process of preparation of the formulation is also provided.
    Type: Application
    Filed: April 5, 2019
    Publication date: April 8, 2021
    Inventors: Geena MALHOTRA, Kalpana JOSHI, Preeti RAUT, Jeevan GHOSALKAR, Neeta DIXIT
  • Publication number: 20210038619
    Abstract: An oral or injectable pharmaceutical composition is provided for treating diseases caused by retroviruses or hepatitis B viruses. The composition comprises a therapeutically effective amount of at least one anti-retroviral drug and a therapeutically effective amount of at least one pharmacokinetic booster or enhancer or derivative thereof. Methods and kits are also provided.
    Type: Application
    Filed: October 15, 2020
    Publication date: February 11, 2021
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar, Preeti Raut
  • Publication number: 20200405729
    Abstract: Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include administering to a patient in need thereof an effective amount of desipramine or a salt thereof. The compositions include an effective amount of desipramine or a salt thereof, in some instances combined with one or more additional agents for the treatment of pulmonary hypertension.
    Type: Application
    Filed: September 16, 2020
    Publication date: December 31, 2020
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Patent number: 10857113
    Abstract: Methods of treating renal cancer, including renal cell carcinoma, using bezafibrate are disclosed herein. Bezafibrate can be administered as a monotherapy or as part of a comprehensive treatment program, which can also include administration with other anti-cancer drugs, surgical treatments or exposure to ionizing radiation.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: December 8, 2020
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Patent number: 10709715
    Abstract: Disclosed herein are methods of treating pulmonary hypertension, including pulmonary arterial hypertension, by administering to a patient in need thereof an effective amount of temozolomide, optionally in conjunction with one or more additional therapeutic agents. Compositions and kits including temozolomide for use in treating pulmonary hypertension, including pulmonary arterial hypertension, are also disclosed.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: July 14, 2020
    Assignee: Cipla Limited
    Inventors: Geena Malhotra, Kalpana Joshi, Jeevan Ghosalkar
  • Publication number: 20200215074
    Abstract: Disclosed herein are methods for treating cancer in a subject in need thereof by administering an agent or pharmaceutically acceptable derivative thereof, optionally with another agent, induces prostate apoptosis response-4 (Par-4) production by non-cancerous normal cells, to promote apoptosis in cancer cells.
    Type: Application
    Filed: June 22, 2018
    Publication date: July 9, 2020
    Inventors: Geena MALHOTRA, Kalpana JOSHI, Jeevan GHOSALKAR
  • Publication number: 20200155557
    Abstract: The present invention is concerned with the treatment of Pulmonary Arterial Hypertension (PAH) by administering Paliperidone. The instant invention further relates to use of a pharmaceutical composition comprising Paliperidone, for the treatment of PAH.
    Type: Application
    Filed: January 22, 2020
    Publication date: May 21, 2020
    Inventors: Karl Roberts, Geena Malhotra, Dhiraj Abhyankar, Kalpana Joshi, Jeevan Ghosalkar
  • Publication number: 20200113919
    Abstract: The invention relates to pharmaceutical compositions comprising ((((((R)-1-(6-amino-9H-purin-9-yl) propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)oxy)methyl pivalate or a pharmaceutically acceptable derivative thereof, optionally with an additional agent, methods of making them, and their use in medicine.
    Type: Application
    Filed: June 29, 2018
    Publication date: April 16, 2020
    Inventors: Geena MALHOTRA, Kalpana JOSHI, Jeevan GHOSALKAR, Atul DAROI, Siddharth AGRAWAL