Patents by Inventor Jeff DeFalco

Jeff DeFalco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES THAT BIND TUMOR TISSUE FOR DIAGNOSIS AND THERAPY
    Publication number: 20230140035
    Abstract: Provided herein are antibodies that bind to tumor tissue through a binding interaction with an extracellular RNA-protein complex. Such antibodies are used in methods of inducing an immune response and methods of inhibiting tumor cell growth. Additionally provided are methods of producing such antibodies.
    Type: Application
    Filed: September 26, 2022
    Publication date: May 4, 2023
    Inventors: Jeff DeFalco, Daniel Eric Emerling, Jessica Finn, Norman Michael Greenberg, Vera Huang, Shaun M. Lippow, Fengling Liu, Amy Manning-Bog, William H. Robinson, Alexander Scholz, Tito Serafini, Nikhil Vad, Wayne Volkmuth, Yann Chong TAN
  • Antibodies that bind tumor tissue for diagnosis and therapy
    Patent number: 11472885
    Abstract: Provided herein are antibodies that bind to tumor tissue through a binding interaction with an extracellular RNA-protein complex. Such antibodies are used in methods of inducing an immune response and methods of inhibiting tumor cell growth. Additionally provided are methods of producing such antibodies.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: October 18, 2022
    Assignee: Atreca, Inc.
    Inventors: Jeff DeFalco, Daniel Eric Emerling, Jessica Finn, Norman Michael Greenberg, Vera Huang, Shaun M. Lippow, Fengling Liu, Amy Manning-Bog, William H. Robinson, Alexander Scholz, Tito Serafini, Yann Chong Tan, Nikhil Vad, Wayne Volkmuth
  • USE OF NANOEXPRESSION TO INTERROGATE ANTIBODY REPERTOIRES
    Publication number: 20220155319
    Abstract: Disclosed herein are methods and compositions for using nanoexpression to interrogate antigen specificity within antibody repertoires. Also disclosed herein is an antibody display system composition comprising one or more recombinant nucleic acid sequences comprising a first nucleic acid sequence encoding a heavy chain variable region sequence or fragment thereof operatively linked to a first identification region sequence and a second nucleic acid sequence encoding a light chain variable region sequence or fragment thereof operatively linked to a second identification region sequence.
    Type: Application
    Filed: January 31, 2022
    Publication date: May 19, 2022
    Inventors: Jeff DeFALCO, Daniel EMERLING, Shaun LIPPOW, Sean CARROLL, Wayne VOLKMUTH, Norm GREENBERG, Tito SERAFINI
  • USE OF NANOEXPRESSION TO INTERROGATE ANTIBODY REPERTOIRES
    Publication number: 20200355698
    Abstract: Disclosed herein are methods and compositions for using nanoexpression to interrogate antigen specificity within antibody repertoires. Also disclosed herein is an antibody display system composition comprising one or more recombinant nucleic acid sequences comprising a first nucleic acid sequence encoding a heavy chain variable region sequence or fragment thereof operatively linked to a first identification region sequence and a second nucleic acid sequence encoding a light chain variable region sequence or fragment thereof operatively linked to a second identification region sequence.
    Type: Application
    Filed: April 9, 2020
    Publication date: November 12, 2020
    Inventors: Jeff DeFalco, Daniel Emerling, Shaun Lippow, Sean Carroll, Wayne Volkmuth, Norm Greenberg, Tito Serafini
  • ANTIBODIES THAT BIND TUMOR TISSUE FOR DIAGNOSIS AND THERAPY
    Publication number: 20200325242
    Abstract: Provided herein are antibodies that bind to tumor tissue through a binding interaction with an extracellular RNA-protein complex. Such antibodies are used in methods of inducing an immune response and methods of inhibiting tumor cell growth. Additionally provided are methods of producing such antibodies.
    Type: Application
    Filed: February 14, 2020
    Publication date: October 15, 2020
    Inventors: Jeff DeFalco, Daniel Eric Emerling, Jessica Finn, Norman Michael Greenberg, Vera Huang, Shaun M. Lippow, Fengling Liu, Amy Manning-Bog, William H. Robinson, Alexander Scholz, Tito Serafini, Yann Chong Tan, Nikhil Vad, Wayne Volkmuth
  • Use of nanoexpression to interrogate antibody repertoires
    Patent number: 10620219
    Abstract: Disclosed herein are methods and compositions for using nanoexpression to interrogate antigen specificity within antibody repertoires. Also disclosed herein is an antibody display system composition comprising one or more recombinant nucleic acid sequences comprising a first nucleic acid sequence encoding a heavy chain variable region sequence or fragment thereof operatively linked to a first identification region sequence and a second nucleic acid sequence encoding a light chain variable region sequence or fragment thereof operatively linked to a second identification region sequence.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: April 14, 2020
    Assignee: ATRECA, INC.
    Inventors: Jeff DeFalco, Daniel Emerling, Shaun Lippow, Sean Carroll, Wayne Volkmuth, Norm Greenberg, Tito Serafini
  • USE OF NANOEXPRESSION TO INTERROGATE ANTIBODY REPERTOIRES
    Publication number: 20180100864
    Abstract: Disclosed herein are methods and compositions for using nanoexpression to interrogate antigen specificity within antibody repertoires. Also disclosed herein is an antibody display system composition comprising one or more recombinant nucleic acid sequences comprising a first nucleic acid sequence encoding a heavy chain variable region sequence or fragment thereof operatively linked to a first identification region sequence and a second nucleic acid sequence encoding a light chain variable region sequence or fragment thereof operatively linked to a second identification region sequence.
    Type: Application
    Filed: December 13, 2017
    Publication date: April 12, 2018
    Inventors: Jeff DeFALCO, Daniel EMERLING, Shaun LIPPOW, Sean CARROLL, Wayne VOLKMUTH, Norm GREENBERG, Tito SERAFINI
  • Use of Nanoexpression to Interrogate Antigen Repertoires
    Publication number: 20150011405
    Abstract: Disclosed herein are methods and compositions for using nanoexpression to interrogate antigen specificity within antibody repertoires. Also disclosed herein is an antibody display system composition comprising one or more recombinant nucleic acid sequences comprising a first nucleic acid sequence encoding a heavy chain variable region sequence or fragment thereof operatively linked to a first identification region sequence and a second nucleic acid sequence encoding a light chain variable region sequence or fragment thereof operatively linked to a second identification region sequence.
    Type: Application
    Filed: June 30, 2014
    Publication date: January 8, 2015
    Inventors: Jeff DeFalco, Tito Serafini, Wayne Volkmuth
  • Neural tracing with a conditional herpesvirus and methods and uses thereof
    Publication number: 20030054340
    Abstract: The present invention relates to methods for tracing or characterization of neural circuits or neural connections across synapses. The invention relates to recombinant neurotropic viruses which are useful in tracing or characterizing neural connections across multiple synapses.
    Type: Application
    Filed: March 28, 2002
    Publication date: March 20, 2003
    Inventors: Jeffrey M. Friedman, Jeff DeFalco, Lynn W. Enquist, Mark Tomishima