Patents by Inventor Jeff Gray

Jeff Gray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200292560
    Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of Proheparin-binding EGF-like growth factor, Tenascin C, Angiopoietin-related protein 4, Fibroblast growth factor 19, Fibroblast growth factor 21, Heparin-binding growth factor 1, Angiopoietin-related protein 6, Proepiregulin, Probetacellulin, Amphiregulin, Angiogenin, Thrombospondin-2, and Collagen alpha-1 (XVIII) chain as diagnostic and prognostic biomarkers in renal injuries.
    Type: Application
    Filed: April 10, 2020
    Publication date: September 17, 2020
    Applicant: ASTUTE MEDICAL, INC.
    Inventors: JOSEPH ANDERBERG, JEFF GRAY, PAUL MCPHERSON, KEVIN NAKAMURA, JAMES PATRICK KAMPF
  • Publication number: 20200138600
    Abstract: Insertion tool assemblies for positioning an implant at a target location in a patient. Insertion tool assemblies that comprise first and second jaw portions configured to engage an implant; a sleeve assembly coupled to the first and second jaw portions; and a handle coupled to the sleeve assembly.
    Type: Application
    Filed: January 6, 2020
    Publication date: May 7, 2020
    Inventors: Mark Weiman, Christopher Angelucci, Jason Gray, Noah Hansell, Jeff Bennett, Cameron Salzberger
  • Publication number: 20200103415
    Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more of Metalloproteinase inhibitor 1, Metalloproteinase inhibitor 2, Metalloproteinase inhibitor 4, C—C motif chemokine 15, C—C motif chemokine 18, C—C motif chemokine 23, and/or, C—C motif chemokine 24 as diagnostic and prognostic biomarker assays in renal injuries.
    Type: Application
    Filed: February 6, 2018
    Publication date: April 2, 2020
    Applicant: ASTUTE MEDICAL, INC.
    Inventors: JOSEPH ANDERBERG, PAUL MCPHERSON, JAMES PATRICK KAMPF, KEVIN NAKAMURA, JEFF GRAY, THOMAS KWAN
  • Publication number: 20200064360
    Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect Chitinase-3-like protein 1 as diagnostic and prognostic biomarker assays in renal injuries.
    Type: Application
    Filed: November 11, 2019
    Publication date: February 27, 2020
    Applicant: ASTUTE MEDICAL, INC.
    Inventors: JOSEPH ANDERBERG, JEFF GRAY, PAUL MCPHERSON, KEVIN NAKAMURA, JAMES PATRICK KAMPF
  • Publication number: 20200046217
    Abstract: A system may include a retractor movable between a radially-collapsed configuration and a radially-expanded configuration, a retraction tool having a tissue-engaging element and an anchor-engaging element, and a first member configured to form a releasable coupling with the anchor-engaging element at each of a plurality of spaced apart positions.
    Type: Application
    Filed: August 6, 2019
    Publication date: February 13, 2020
    Inventors: Art Butcher, Paul Smith, Ryan V. Wales, Jeff Gray, Scott E. Brechbiel, Sean P. Fleury, Laura E. Christakis, Gary A. Jordan
  • Patent number: 10548744
    Abstract: Insertion tool assemblies for positioning an implant at a target location in a patient. Insertion tool assemblies that comprise first and second jaw portions configured to engage an implant; a sleeve assembly coupled to the first and second jaw portions; and a handle coupled to the sleeve assembly.
    Type: Grant
    Filed: November 1, 2016
    Date of Patent: February 4, 2020
    Assignee: Globus Medical, Inc.
    Inventors: Mark Weiman, Christopher Angelucci, Jason Gray, Noah Hansell, Jeff Bennett, Cameron Salzberger
  • Publication number: 20190388726
    Abstract: Handle grip are configured to interface to the end of a bar allowing a user to employ the bar for motion, exercise, stretching or other activity. For example, the handle grips may slip onto the bar under force. The handle grips include a grip section, configured to provide a surface the user can grab. Accordingly, the grip surface may include features that increase the effective friction coefficient. The handle grip also includes an end section configured to react both axial and lateral loads applied by the user via the grip section. The bar can be sectioned, making storage and transport easier. Accordingly, the sectioned bar can be assembly to provide the desired length of exercise bar.
    Type: Application
    Filed: June 25, 2018
    Publication date: December 26, 2019
    Inventors: Jeff Mains, Neal Valera, Mitch Taylor, Dennis Dunphy, Randy Hew, Mike Schroder, Frank Gray
  • Publication number: 20190353667
    Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more of Angiopoietin-related protein 6, Complement C5, Fibroblast growth factor 21, Fibroblast growth factor 23, Pro-interleukin-16, C—X—C motif chemokine 9, Hepatocyte growth factor-like protein, and/or Tumor necrosis factor receptor superfamily member 1 IB as diagnostic and prognostic biomarker assays in renal injuries.
    Type: Application
    Filed: February 6, 2018
    Publication date: November 21, 2019
    Applicant: ASTUTE MEDICAL, INC.
    Inventors: JOSEPH ANDERBERG, PAUL MCPHERSON, JAMES PATRICK KAMPF, KEVIN NAKAMURA, JEFF GRAY, THOMAS KWAN
  • Patent number: 10473671
    Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect Chitinase-3-like protein 1 as diagnostic and prognostic biomarker assays in renal injuries.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: November 12, 2019
    Assignee: Astute Medical, Inc.
    Inventors: Joseph Anderberg, Jeff Gray, Paul McPherson, Kevin Nakamura, James Patrick Kampf
  • Publication number: 20190298364
    Abstract: The present disclosure relates generally to the field of medical devices and establishing fluid communication between body lumens. In particular, the present disclosure relates to devices and methods for establishing a controlled flow or access passage between body lumens.
    Type: Application
    Filed: March 22, 2019
    Publication date: October 3, 2019
    Inventors: Michael Walsh, Darren Curran, Otto Van Der Kooij, Daniel Tuck, Javier Palomar-Moreno, Jeff Gray, Martyn Folan, Emma J. Mooney, Enda Hannon
  • Publication number: 20190282223
    Abstract: Medical devices and methods of using medical devices are disclosed. An example tissue retraction delivery device includes a positioning assembly, the assembly including: a delivery catheter having a distal end region and a lumen extending therein, wherein the distal end region includes an engagement member orienting tip. The delivery device also includes an actuation catheter extending within at least a portion of the delivery catheter, the actuation catheter including a distal end region and a lumen extending therein. An actuation wire extends within the lumen of the actuation catheter, the actuation wire having a proximal end region and a distal end region. An end effector is coupled to the distal end region of the actuation wire, the end effector configured to capture an engagement member of a tissue retraction device, wherein manipulation of the actuation wire shifts the end effector from a first position to a second closed position.
    Type: Application
    Filed: March 13, 2019
    Publication date: September 19, 2019
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: SAMUEL RAYBIN, RYAN WALES, PAUL SMITH, JEFF GRAY, SEAN P. FLEURY, SCOTT E. BRECHBIEL
  • Patent number: 10413702
    Abstract: A drainage catheter, comprising an elongate body member, an elongate flexible member and a hub, the hub including a base and a collar, the base an internal passageway and a side lumen and an outer surface including an engagement element and a mating surface portion, and the collar including a side lumen extending from the inner surface to the outer surface and wherein the inner surface of the collar includes a mating surface portion and a counter element, wherein the elongate flexible member extends through the side lumen side lumens, and wherein the hub has an unlocked position where the engagement element and the counter element are not engaged and a locked position where the engagement element and the counter element are engaged, the collar is tightened on the base and the elongate flexible element is clamped between the mating surface portions of the base and the collar.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: September 17, 2019
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Jeff Gray, Alison Lepordo, Nathan Zamarripa, Karla Weaver, Thomas Pepin
  • Publication number: 20190265253
    Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury.
    Type: Application
    Filed: December 31, 2018
    Publication date: August 29, 2019
    Applicant: ASTUTE MEDICAL, INC.
    Inventors: Joseph Anderberg, Jeff Gray, Paul McPherson, Kevin Nakamura, James Patrick Kampf
  • Publication number: 20190250170
    Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more biomarkers selected from the group consisting of Immumoglobulin A, Metalloproteinase inhibitor 4, and Thrombomodulin as diagnostic and prognostic biomarker assays in renal injuries.
    Type: Application
    Filed: January 18, 2019
    Publication date: August 15, 2019
    Applicant: ASTUTE MEDICAL, INC.
    Inventors: Joseph Anderberg, Jeff Gray, Paul McPherson, Kevin Nakamura, James Patrick Kampf
  • Publication number: 20190227056
    Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more of hyaluronic acid (HA) as diagnostic and prognostic biomarker assays in renal injuries.
    Type: Application
    Filed: January 18, 2019
    Publication date: July 25, 2019
    Applicants: ASTUTE MEDICAL, INC., THE UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: JOSEPH ANDERBERG, JEFF GRAY, PAUL MCPHERSON, KEVIN NAKAMURA, JAMES PATRICK KAMPF, KAI SINGBARTL, JOHN A. KELLUM
  • Patent number: 10324093
    Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of Cathepsin B, Renin, Dipeptidyl Peptidase IV, Neprilysin, Beta-2-microglobulin, Carbonic anhydrase IX, and C-X-C motif chemokine 2 as diagnostic and prognostic biomarkers in renal injuries.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: June 18, 2019
    Assignee: Astute Medical, Inc.
    Inventors: Joseph Anderberg, Jeff Gray, Paul McPherson, Kevin Nakamura, James Patrick Kampf
  • Publication number: 20190120858
    Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect Chitinase-3-like protein 1 as a predictive biomarker in renal injuries.
    Type: Application
    Filed: December 21, 2018
    Publication date: April 25, 2019
    Applicant: ASTUTE MEDICAL, INC.
    Inventors: Joseph Anderberg, Jeff Gray, Paul McPherson, Kevin Nakamura, James Patrick Kampf
  • Patent number: 10251666
    Abstract: The present disclosure provides systems and methods for cutting mucosal tissue. In particular, the present disclosure provides an endoscopic hood with an integrated wire for single-step tissue cutting. The endoscopic hood is particularly useful for performing repeated cutting, for example EMR resections, without the need for assistance by a nurse or medical technician.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: April 9, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Jeff Gray, Samuel Raybin, Kevin Scott Gell, Paul Smith
  • Publication number: 20190059925
    Abstract: A system for controlling the flow of fluid through a medical device may include a medical device having a lumen that extends to a distal end of the medical device; a fluid source configured to supply fluid having a positive pressure to the lumen of the medical device; and a flow controller configured to apply a negative pressure to the fluid within the lumen, wherein the flow controller is triggered to apply the negative pressure upon a lowering of the positive pressure from the fluid source.
    Type: Application
    Filed: August 24, 2018
    Publication date: February 28, 2019
    Applicant: Boston Scientific Scimed, Inc.
    Inventors: Paul Smith, Ryan V. Wales, Sean P. Fleury, Laura Elizabeth Christakis, Scott E. Brechbiel, Jeff Gray, Mingxiang Xu
  • Publication number: 20190060620
    Abstract: The present disclosure relates generally to the field of medical devices and establishing fluid communication between body lumens and/or within a body vessel. In particular, the present disclosure relates to devices and methods for establishing drainage between apposed body lumens and/or within a body vessel.
    Type: Application
    Filed: August 29, 2018
    Publication date: February 28, 2019
    Inventors: Jeff Gray, Scott E. Brechbiel, Paul Smith, Laura E. Christakis, Ryan V. Wales, Sean P. Fleury, Bryan Bannon, Anand V. Sahai