Abstract: Various embodiments are generally directed to fluid container adapters that couple with a fluid container, so to enable access to the contents of the fluid container, such as from an endoscopic system via a tubing set. Several embodiments are particularly directed to a fluid container adapter that can couple with an opening in a variety of fluid containers to place one or more tubes in fluid communication with an interior of any particular one of the variety of fluid containers.

Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of Coagulation factor VII, CA 19-9, Insulin-like growth factor-binding protein 7, C-X-C motif chemokine 6, and C-C motif chemokine 13 as diagnostic and prognostic biomarkers in renal injuries.

Abstract: A method of determining the location of a plurality of tagged items in a storage system comprises scanning (540) for tags with a first antenna at a plurality of power levels, analysing (560) the scan to identify each tag of interest sighted by the first antenna at each power level of the plurality of power levels, and scanning (540) for tags with at least one further antenna at a plurality of power levels. The method further comprises analysing (560) the further scan to identify each tag of interest sighted by each further antenna at each power level of the plurality of power levels, further analysing (560) the scan to determine the antenna with the lowest power level that identified each tag of interest, and estimating a position (580) of each tag of interest using the determined antenna and the lowest power level that identified that tag.

Abstract: The present disclosure relates generally to the field of medical devices and establishing fluid communication between body lumens. In particular, the present disclosure relates to devices and methods for establishing a controlled flow or access passage between body lumens.

Abstract: The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using as says that detect Chitinase-3-like protein 1 as diagnostic and prognostic biomarker assays in renal injuries.

Abstract: A medical device may include a tube defining a lumen. The tube may be configured to couple to a source of suction. The medical device may include a porous body coupled to a distal portion of the tube. The porous body may include a plurality of openings in fluid communication with the lumen. The medical device may further include a wire coupled to the distal portion of the tube. The wire may be configured to move the distal portion of the tube and the porous body via a pulling force applied to the wire. The pulling force applied to the wire may exert a force on the tube that is at a non-zero angle relative to a central longitudinal axis of the tube.

Abstract: A system for controlling the flow of fluid through a medical device may include a medical device having a lumen that extends to a distal end of the medical device; a fluid source configured to supply fluid having a positive pressure to the lumen of the medical device; and a flow controller configured to apply a negative pressure to the fluid within the lumen, wherein the flow controller is triggered to apply the negative pressure upon a lowering of the positive pressure from the fluid source.

Abstract: A medical device may include a shaft extending from a proximal end toward a distal end, the shaft including a lumen extending from the proximal end toward the distal end; a first stapling head at the distal end, the first stapling head configured to contain one or more staples, and the first stapling head having a block disposed within, and movable relative to, the first stapling head; a second stapling head at the distal end; and a pushing element extending through the lumen, the pushing element being movable from a first position to a second position, wherein transition of the pushing element from the first position to the second position urges the block to move toward second stapling head to deploy the one or more staples.

Abstract: The present disclosure relates generally to the field of medical devices and establishing fluid communication between body lumens. In particular, the present disclosure relates to devices and methods for establishing a controlled flow or access passage between body lumens.

Abstract: A fastening device may comprise a flexible longitudinal body including a central longitudinal axis and a distal end; an anvil extending distally from the distal end of longitudinal body; and a distal body extending distally from the distal end of the longitudinal body. The distal body may be configured to removably receive a cartridge having a plurality of fasteners. At least one of the anvil and the distal body may be flexible and may have a first configuration with a distal portion of the at least one of the anvil and the distal body extending radially outward from the central longitudinal axis and a second configuration with the distal portion closer to the central longitudinal axis than in the first configuration.

Abstract: The present disclosure relates generally to the field of medical devices and establishing fluid communication between body lumens. In particular, the present disclosure relates to devices and methods for placing the muscularis layers of first and second body lumens in contact to establish a long term or permanent open flow or access passage therebetween.

Abstract: A medical device comprising a shaft, a handle including a proximal portion and a distal portion, wherein the distal portion is fixed to a proximal portion of the shaft, and a channel extending from the handle into the shaft, wherein the channel includes a proximal channel and a distal channel, the proximal channel being rotatable relative to the distal channel and aligned with the distal channel throughout rotation of the proximal channel, wherein the proximal portion includes the proximal channel and the distal portion includes the distal channel, wherein the distal portion is rotatable relative to the proximal portion of the handle, and the shaft is configured to rotate with the distal portion of the handle.

Abstract: A medical device may include a shaft extending from a proximal end toward a distal end, the shaft including a lumen extending from the proximal end toward the distal end; a first stapling head at the distal end, the first stapling head configured to contain one or more staples, and the first stapling head having a block disposed within, and movable relative to, the first stapling head; a second stapling head at the distal end; and a pushing element extending through the lumen, the pushing element being movable from a first position to a second position, wherein transition of the pushing element from the first position to the second position urges the block to move toward second stapling head to deploy the one or more staples.

Abstract: A medical device that comprises a rim defining a loop in a plane and defining a width measured perpendicular to the plane, at least one wire coupled to a distal end of the rim and extending proximally from the distal end out of the plane to a proximal end of the rim, the at least one wire having a cross-sectional dimension measured perpendicular to a longitudinal axis of the at least one wire, the cross-sectional dimension being smaller than the width of the rim, and a sheath configured to cover at least a portion of the rim and a portion of the at least one wire.

Abstract: A fastening device may comprise a flexible longitudinal body including a central longitudinal axis and a distal end; an anvil extending distally from the distal end of longitudinal body; and a distal body extending distally from the distal end of the longitudinal body. The distal body may be configured to removably receive a cartridge having a plurality of fasteners. At least one of the anvil and the distal body may be flexible and may have a first configuration with a distal portion of the at least one of the anvil and the distal body extending radially outward from the central longitudinal axis and a second configuration with the distal portion closer to the central longitudinal axis than in the first configuration.

Abstract: A medical device comprising a shaft, a handle including a proximal portion and a distal portion, wherein the distal portion is fixed to a proximal portion of the shaft, and a channel extending from the handle into the shaft, wherein the channel includes a proximal channel and a distal channel, the proximal channel being rotatable relative to the distal channel and aligned with the distal channel throughout rotation of the proximal channel, wherein the proximal portion includes the proximal channel and the distal portion includes the distal channel, wherein the distal portion is rotatable relative to the proximal portion of the handle, and the shaft is configured to rotate with the distal portion of the handle.

Abstract: A device for administering a fluid to a patient anatomy includes a flexible catheter. The catheter includes a lumen extending therethrough. The catheter is sized and shaped to extend from a proximal end outside a human body to a distal end that can be guided to a target location. A distal portion of the catheter includes one or more exit ports communicating with a first lumen for administering the fluid. A deformable portion of the catheter is formed so that, in a first state, the deformable portion assumes a first shape suitable for guiding the catheter to the target location and, in a second state, the deformable portion assumes a second shape in which the deformable portion curves to extend in at least one radial direction for engaging an inner wall of the target location to anchor the catheter in the target location while administering the fluid.

Abstract: A device includes a flexible catheter and a material. The catheter includes at least a first channel extending therethrough and is sized and shaped to extend from a proximal end outside a human body to a distal end that can be guided to a target location within a gastrointestinal (GI) system. A first distal portion of the catheter includes at least one exit port communicating with the first channel for administering a fluid to a patient anatomy. The material is fixed to an exterior of the catheter or ejectable from an interior of the catheter into the location that, in a first state or shape, is suitable for guiding the catheter to the location and, in a second state or shape, is suitable for engaging an inner wall of the location to anchor the catheter in the location while administering the fluid via the first channel.

Abstract: A device includes a flexible catheter and at least one wirefrom. The catheter includes a first lumen extending therethrough and is sized and shaped to extend to a target location within a gastrointestinal (GI) system. A first distal portion of the catheter includes one or more exit ports communicating with the first lumen for administering a fluid to the location. The wireform is attached around the catheter or deployable from within the catheter, the wireform being formed so that, in a first state, the wireform assumes a first shape suitable for guiding the catheter to the location and, in a second state, the wireform assumes a second shape in which the wire extends away from the catheter in at least one radial direction for contacting a wall of the location to anchor the catheter in the location while administering the fluid via the first lumen.

Abstract: A medical device that comprises a rim defining a loop in a plane and defining a width measured perpendicular to the plane, at least one wire coupled to a distal end of the rim and extending proximally from the distal end out of the plane to a proximal end of the rim, the at least one wire having a cross-sectional dimension measured perpendicular to a longitudinal axis of the at least one wire, the cross-sectional dimension being smaller than the width of the rim, and a sheath configured to cover at least a portion of the rim and a portion of the at least one ware.