Abstract: The invention discloses diagnostic techniques based on single cell genomics, consisting of obtaining a blood sample, enriching a sub-population of cells present in the blood sample, sequestering individual cells or group of cells from the blood sample, obtaining sequencing data from the sequestered cells or group of cells, using genetic variant information to determine the provenance of the cells, and genetically analyzing the cells of the correct provenance to provide a diagnostic readout. Using the cell-based testing techniques of the invention, the number of false positives is greatly reduced when compared to cell-free DNA (cfDNA) based traditional testing techniques. The invention may be effectively employed for non-invasive prenatal (NIPT) diagnostics, oncological testing and other diagnostic procedures.

Abstract: The invention discloses diagnostic techniques based on single cell genomics, consisting of obtaining a blood sample, enriching a sub-population of cells present in the blood sample, sequestering individual cells or group of cells from the blood sample, obtaining sequencing data from the sequestered cells or group of cells, using genetic variant information to determine the provenance of the cells, and genetically analyzing the cells of the correct provenance to provide a diagnostic readout. Using the cell-based testing techniques of the invention, the number of false positives is greatly reduced when compared to cell-free DNA (cfDNA) based traditional testing techniques. The invention may be effectively employed for non-invasive prenatal (NIPT) diagnostics, oncological testing and other diagnostic procedures.

Abstract: The invention discloses diagnostic techniques based on single cell genomics, consisting of obtaining a blood sample, enriching a sub-population of cells present in the blood sample, sequestering individual cells or group of cells from the blood sample, obtaining sequencing data from the sequestered cells or group of cells, using genetic variant information to determine the provenance of the cells, and genetically analyzing the cells of the correct provenance to provide a diagnostic readout. Using the cell-based testing techniques of the invention, the number of false positives is greatly reduced when compared to cell-free DNA (cfDNA) based traditional testing techniques. The invention may be effectively employed for non-invasive prenatal (NIPT) diagnostics, oncological testing and other diagnostic procedures.

Abstract: The invention discloses diagnostic techniques based on single cell genomics, consisting of obtaining a blood sample, enriching a sub-population of cells present in the blood sample, sequestering individual cells or group of cells from the blood sample, obtaining sequencing data from the sequestered cells or group of cells, using genetic variant information to determine the provenance of the cells, and genetically analyzing the cells of the correct provenance to provide a diagnostic readout. Using the cell-based testing techniques of the invention, the number of false positives is greatly reduced when compared to cell-free DNA (cfDNA) based traditional testing techniques. The invention may be effectively employed for non-invasive prenatal (NIPT) diagnostics, oncological testing and other diagnostic procedures.

Abstract: An ignition system and method of igniting the ignition system includes a main catalyst section in a staged relationship with a pilot-catalyst section to stage a decomposition though the pilot-catalyst section which preheats the main catalyst section.

Abstract: Systems and a method for printing and applying labels on packages. The system includes a conveyor configured to transport a plurality of packages, one or more scanners configured to scan the plurality of packages, and one or more print and apply stations. The one or more print and apply stations includes a printer configured to print labels, and an applier configured to apply the labels on the plurality of packages. The system further includes a management controller configured to retrieve promotion data for the plurality of packages, transmit the promotion data and spooling instructions associated with the promotion data to a print controller, and control operation of the conveyor in synchronization with the spooling instructions, and the print controller. The print controller is configured to manage and spool the promotion data to the one or more print and apply stations.

Abstract: A method for placing targeted advertisements on parcel packages moving on a conveyor. The method includes electronically scanning, via a processing device, information regarding one or more packages to be delivered to one or more recipients. Promotion data regarding one or more promotions targeted to the one or more recipients is retrieved. An arrival time for the one or more packages to arrive at a print station is determined based on a rate at which the one or more packages are moving on the conveyor. The promotion data is spooled to the print station at a spool time based on the arrival time. The one or more promotion labels associated with the promotion data are applied on the one or more packages at the print station in synchronization with the package movement rate.

Abstract: The conversion of linear polarized light into radial-polarized light is accomplished through a radial polarization generator containing multiple layers of polarizing film, or polarization converters, for converting the beam of light to a different orientation. Using the radial polarization generator, a quasi radial-polarized beam of light can be obtained quickly and easily by simply aligning the light at the center of the polarization generator. True radial-polarization can be obtained by passing the laser through a spatial filter. With such a radial polarization generator, a large frequency range of light may be converted from a linear orientation to a radial orientation.

Abstract: Methods and apparatus for converting linear polarized light into radial-polarized light are disclosed. The polarization is accomplished through a radial polarization generator containing multiple layers of polarizing film, or polarization converters, for converting the beam of light to a different orientation. Using the radial polarization generator, a quasi radial-polarized beam of light can be obtained quickly and easily by simply aligning the light at the center of the polarization generator. True radial-polarization can be obtained by passing the laser through a spatial filter. With such a radial polarization generator, a large frequency range of light may be converted from a linear orientation to a radial orientation.

Abstract: An ignition system and method of igniting the ignition system includes a main catalyst section in a staged relationship with a pilot-catalyst section to stage a decomposition though the pilot-catalyst section which preheats the main catalyst section.