Patents by Inventor Jeff L. Froula

Jeff L. Froula has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Long-range barcode labeling-sequencing
    Patent number: 9469874
    Abstract: Methods for sequencing single large DNA molecules by clonal multiple displacement amplification using barcoded primers. Sequences are binned based on barcode sequences and sequenced using a microdroplet-based method for sequencing large polynucleotide templates to enable assembly of haplotype-resolved complex genomes and metagenomes.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: October 18, 2016
    Assignee: The Regents of the University of California
    Inventors: Feng Chen, Tao Zhang, Kanwar K. Singh, Len A. Pennacchio, Jeff L. Froula, Kevin S. Eng
  • Method for Making Mate-Pair Libraries
    Publication number: 20120329678
    Abstract: The present disclosure provides methods for generating mate-pair libraries using a recombinase/recombination site system. The method allows for increased insert size, improved efficiency and simplicity of the steps involved, and improved data generation. Mate-pair libraries are helpful in providing positional information for the assembly of sequence data from short read sequencing platforms. The disclosure also embodies the mate-pair libraries as generated from these methods.
    Type: Application
    Filed: June 27, 2012
    Publication date: December 27, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Feng Chen, Ze Peng, Zhiying Zhao, Nandita Nath, Jeff L. Froula