Patents by Inventor Jeff Leid

Jeff Leid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protective vaccine against biofilms comprising cell wall-associated immunogens
    Patent number: 8318180
    Abstract: Vaccine formulations effective against Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus (MRSA) are disclosed, as well as methods of using the vaccine formulations in the treatment, prevention and prophylaxis of Staphylococcus aureus infections in a subject.
    Type: Grant
    Filed: September 23, 2009
    Date of Patent: November 27, 2012
    Assignees: University of Maryland, Baltimore, Northern Arizona University
    Inventors: Mark E. Shirtliff, Graeme O'May, Jeff Leid
  • PROTECTIVE VACCINE AGAINST STAPHYLOCOCCUS AUREUS BIOFILMS COMPRISING CELL WALL-ASSOCIATED IMMUNOGENS
    Publication number: 20110177111
    Abstract: Vaccine formulations effective against Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus (MRSA) are disclosed, as well as methods of using the vaccine formulations in the treatment, prevention and prophylaxis of Staphylococcus aureus infections in a subject.
    Type: Application
    Filed: September 23, 2009
    Publication date: July 21, 2011
    Applicant: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Mark E. Shirtliff, Graeme O'May, Jeff Leid
  • Methods for stimulating human leukocytes to kill bacteria, yeast and fungi in biofilms that have formed in/on prosthetic devices, catheters, tissues and organs in vivo
    Publication number: 20050214279
    Abstract: The present invention provides a method for stimulating human leukocytes to kill microorganisms in biofilms. The invention also provides a methods, compositions and kits for treating or preventing a biofilm infection in a mammal comprising administering a therapeutically effective amount of a complement protein and one or more antibodies which bind to a bacterial, yeast, fungal, carbohydrate or lipid epitope present in the biofilm. Additionally, the invention provides methods, compositions and kits for treating biofilm infection in a mammal which comprises administering to the mammal a therapeutically effective amount of a complement protein and a conjugate composition. The invention also provides methods for determining Critical Neutrophil Concentration and Neutrophil Extraction Efficiency in a mammal.
    Type: Application
    Filed: September 17, 2004
    Publication date: September 29, 2005
    Inventors: Samuel Silverstein, Jeff Leid, Yongmei Li, John Loike, J. Costerton, Mark Shirtliff