Patents by Inventor Jeff M. Sands

Jeff M. Sands has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210106547
    Abstract: This disclosure relates to managing cardiovascular diseases and conditions associated with kidney disease. In certain embodiments, this disclosure relates to methods of treating or preventing a cardiovascular disease or condition comprising administering an effective amount of a urea transporter inhibitor to a subject in need thereof. In certain embodiments, the subject is diagnosed with kidney disease. In certain embodiments, the subject is diagnosed with uremic cardiomyopathy. In certain embodiments, the urea transporter inhibitor is N,N?-dimethylthiourea (DMTU), prodrug, derivative, or salt thereof.
    Type: Application
    Filed: October 9, 2020
    Publication date: April 15, 2021
    Inventors: Jeff M. Sands, Janet D. Klein, Xiaonan H. Wang
  • Patent number: 10596144
    Abstract: In certain embodiments, the disclosure relates to methods of treating or preventing nephrogenic diabetes insipidus comprising administering an effective amount of a AMPK activator to a subject in need thereof, wherein In certain embodiments, the AMPK activator is metformin or salt thereof. In certain embodiments, the subject has been diagnosed with nephrogenic diabetes insipidus.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: March 24, 2020
    Assignee: Emory University
    Inventors: Jeff M. Sands, Mitsi A. Blount, Janet D. Klein
  • Publication number: 20180092876
    Abstract: In certain embodiments, the disclosure relates to methods of treating or preventing nephrogenic diabetes insipidus comprising administering an effective amount of a AMPK activator to a subject in need thereof, wherein In certain embodiments, the AMPK activator is metformin or salt thereof. In certain embodiments, the subject has been diagnosed with nephrogenic diabetes insipidus.
    Type: Application
    Filed: November 16, 2017
    Publication date: April 5, 2018
    Inventors: Jeff M. Sands, Mitsi A. Blount, Janet D. Klein
  • Patent number: 9827222
    Abstract: In certain embodiments, the disclosure relates to methods of treating or preventing nephrogenic diabetes insipidus comprising administering an effective amount of a AMPK activator to a subject in need thereof, wherein In certain embodiments, the AMPK activator is metformin or salt thereof. In certain embodiments, the subject has been diagnosed with nephrogenic diabetes insipidus.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: November 28, 2017
    Assignee: Emory University
    Inventors: Jeff M. Sands, Mitsi A. Blount, Janet D. Klein
  • Publication number: 20160367516
    Abstract: In certain embodiments, the disclosure relates to methods of treating or preventing nephrogenic diabetes insipidus comprising administering an effective amount of a AMPK activator to a subject in need thereof, wherein In certain embodiments, the AMPK activator is metformin or salt thereof. In certain embodiments, the subject has been diagnosed with nephrogenic diabetes insipidus.
    Type: Application
    Filed: June 27, 2014
    Publication date: December 22, 2016
    Applicant: Emory University
    Inventors: Jeff M. Sands, Mitsi A. Blount, Janet D. Klein