Patents by Inventor Jeff OMEARA

Jeff OMEARA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITION FOR KRAS MODIFICATIONS
    Publication number: 20240092756
    Abstract: Provided herein are compounds binding to KRAS protein or a mutant thereof, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.
    Type: Application
    Filed: November 18, 2021
    Publication date: March 21, 2024
    Inventors: Patrick T. GUNNING, Jeff OMEARA, Siawash AHMAR, Graham L. SIMPSON, Peter HUNT, David Alexander ROSA, Ji Sung PARK
  • BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF
    Publication number: 20240018153
    Abstract: Provided herein are benzenesulfonamide compounds, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.
    Type: Application
    Filed: November 18, 2021
    Publication date: January 18, 2024
    Inventors: Patrick T. GUNNING, Jeff OMEARA, Siawash AHMAR, Graham L. SIMPSON, Peter HUNT, David Alexander ROSA, Ji Sung PARK
  • STAT INIHIBITORY COMPOUNDS AND COMPOSITIONS
    Publication number: 20230265055
    Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for the inhibition of Signal Transducer and Activator of Transcription 5a and 5b (STAT5). Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as, for example, breast cancer, hematological cancer, and pancreatic cancer.
    Type: Application
    Filed: September 3, 2021
    Publication date: August 24, 2023
    Inventors: Roman FLECK, John PROUDFOOT, Jeff OMEARA, Patrick Thomas GUNNING, Ahmed Magdy ALI, David Alexander ROSA, Angel Sampedro PALERM, Alla DARWISH, Alford Antoine JOHN
  • STAT INHIBITORY COMPOUNDS AND COMPOSITIONS
    Publication number: 20230159445
    Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for the inhibition of Signal Transducer and Activator of Transcription 5a and 5b (STAT5). Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as, for example, breast cancer and pancreatic cancer.
    Type: Application
    Filed: March 5, 2021
    Publication date: May 25, 2023
    Inventors: Roman FLECK, John PROUDFOOT, Jeff OMEARA, Krishna Kumar GNANASEKARAN, Patrick Thomas GUNNING, Alford Antoine JOHN, Angel Sampedro PALERM, Alla DARWISH, Dziyana KRASKOUSKAYA, Ahmed Magdy Ahmed Mohamed ALI
  • ALPHA SUBSTITUTED STAT INHIBITORS AND COMPOSITIONS THEREOF
    Publication number: 20230137956
    Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for the inhibition of Signal Transducer and Activator of Transcription 5a and 5b (STAT5). Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as, for example, breast cancer and pancreatic cancer.
    Type: Application
    Filed: March 5, 2021
    Publication date: May 4, 2023
    Inventors: Roman FLECK, John PROUDFOOT, Jeff OMEARA, Patrick Thomas GUNNING, Angel Sampedro PALERM, Alla DARWISH, Dziyana KRASKOUSKAYA
  • PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF
    Publication number: 20230055961
    Abstract: Provided herein are pentafluorobenzenesulfonamide compounds, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.
    Type: Application
    Filed: May 19, 2022
    Publication date: February 23, 2023
    Inventors: Dziyana KRASKOUSKAYA, Siawash AHMAR, Patrick T. GUNNING, Jeff OMEARA, David Alexander ROSA, Ji Sung PARK, Graham L. SIMPSON, Ayah ABDELDAYEM