Patents by Inventor Jeff T. Suri

Jeff T. Suri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210196157
    Abstract: The invention disclosed herein is a device having an analyte sensor, having a working electrode and a membrane disposed over the electrode and methods of using the device. The multilayered membrane is formed by chemically fusing an inner layer of a polyelectrolyte with an outer layer of an ethylenically unsaturated prepolymer through a chain-growth polymerization reaction.
    Type: Application
    Filed: December 29, 2020
    Publication date: July 1, 2021
    Applicant: Glucovation, Inc.
    Inventor: Jeff T. Suri
  • Publication number: 20200371062
    Abstract: Embodiments described herein relate generally to compositions that include a synthetic redox-active receptor, and in particular to compositions that include a boronic acid based synthetic redox-active receptor which can electrochemically sense a target analyte in a sample solution. In some embodiments, a synthetic redox-active receptor can have a composition of formula I: wherein the variables L, R, R?, n and X? are described herein.
    Type: Application
    Filed: July 16, 2020
    Publication date: November 26, 2020
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventor: Jeff T. Suri
  • Patent number: 10761053
    Abstract: Embodiments described herein relate generally to compositions that include a synthetic redox-active receptor, and in particular to compositions that include a boronic acid based synthetic redox-active receptor which can electrochemically sense a target analyte in a sample solution. In some embodiments, a synthetic redox-active receptor can have a composition of formula I: wherein the variables L, L?, R, R?, n and X? are described herein.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: September 1, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventor: Jeff T. Suri
  • Patent number: 10352941
    Abstract: Methods of covalently attaching heparin to a membrane comprising plasma treating the membrane to produce an amino-functionalized membrane; and reacting the amino-functionalized membrane with heparin under conditions in which heparin becomes covalently attached to the amino-functionalized membrane, wherein said heparin is indirectly attached via a spacer to said amino-functionalized membrane and/or said heparin is attached from a single site in said heparin to a single site on said amino-functionalized membrane or to said spacer. Also disclosed are analyte sensors.
    Type: Grant
    Filed: September 25, 2012
    Date of Patent: July 16, 2019
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Jeff T. Suri, Eric Patterson
  • Publication number: 20170273603
    Abstract: In some embodiments, an electrochemical sensing system includes a working electrode and a reference electrode. At least a portion of the working electrode includes rhodium. An electrical circuit is electronically coupled to the working electrode and the reference electrode. The electrical circuit is configured to bias the working electrode at voltage of less than about 0.4 V which is sufficient to electrochemically decompose a target analyte, and to measure a current corresponding to the concentration of the target analyte. In some embodiments, a biosensing molecule can be disposed on the working electrode and is operative to catalytically decompose a non-electroactive target analyte to yield and an electroactive by-product. In some embodiment, the reference electrode can include rhodium and its oxides.
    Type: Application
    Filed: March 12, 2015
    Publication date: September 28, 2017
    Applicant: GLUCOVATION, INC.
    Inventors: Jeff T. Suri, Robert Boock
  • Publication number: 20170273610
    Abstract: An electrochemical sensing system includes a working electrode and a reference electrode, which can at least partially be disposed in a housing. At least a portion of the working electrode includes rhodium metal. An electrical circuit is disposed in the housing and configured to be electronically coupled to the electrodes. The electrical circuit is operative to: (a) bias the working electrode at a voltage of less than about 0.4 V, and (b) measure a current corresponding to the concentration of the target analyte. A communications module is electrically coupled to the electrical circuit and configured to display a concentration of the target analyte, and/or communicate data between the electrical circuit and an external device. The electrodes are movable between a first configuration in which the electrodes are substantially disposed inside the housing, and a second configuration in which at least a portion of the electrodes is disposed outside the housing.
    Type: Application
    Filed: March 12, 2015
    Publication date: September 28, 2017
    Inventors: Jeff T. Suri, Robert Boock, Kenneth San Vicente
  • Publication number: 20170219521
    Abstract: Embodiments described herein relate generally to compositions that include a synthetic redox-active receptor, and in particular to compositions that include a boronic acid based synthetic redox-active receptor which can electrochemically sense a target analyte in a sample solution. In some embodiments, a synthetic redox-active receptor can have a composition of formula I: wherein the variables L, L?, R, R? n and X are described herein.
    Type: Application
    Filed: April 23, 2015
    Publication date: August 3, 2017
    Inventor: Jeff T. Suri
  • Publication number: 20170188923
    Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The enzyme layer protects the enzyme and prevents it from leaching from the sensing membrane into a host or deactivating.
    Type: Application
    Filed: December 29, 2016
    Publication date: July 6, 2017
    Inventors: Jiong Zou, Robert J. Boock, Andrew Trinin Dennis, Ted Tang Lee, Jeff T. Suri, David Sze, Mark A. Tapsak, Huashi Zhang, Shanger Wang
  • Publication number: 20170188916
    Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises a biointerface layer which interfaces with a biological fluid containing the analyte to be measured. The biointerface layer can comprises a biointerface polymer, wherein the biointerface polymer comprises polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The sensing membrane can also comprise an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The sensing membrane can also comprise a diffusion-resistance layer, which can comprise a base polymer having a lowest Tg of greater than ?50 C.
    Type: Application
    Filed: December 30, 2016
    Publication date: July 6, 2017
    Inventors: Shanger Wang, Robert J. Boock, Andrew Trinin Dennis, Ted Tang Lee, Jeff T. Suri, David Sze, Mark A Tapsak, Huashi Zhang, Jiong Zou
  • Publication number: 20170191955
    Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The enzyme layer protects the enzyme and prevents it from leaching from the sensing membrane into a host or deactivating.
    Type: Application
    Filed: December 29, 2016
    Publication date: July 6, 2017
    Inventors: Jiong Zou, Robert J. Boock, Andrew Trinin Dennis, Ted Tang Lee, Jeff T. Suri, David Sze, Mark A. Tapsak, Huashi Zhang, Shanger Wang
  • Patent number: 8983565
    Abstract: Embodiments of the present invention are directed to an optical sensor capable of measuring two analytes simultaneously with a single indicator system. In preferred embodiments, the sensor comprises a fluorescent dye having acid and base forms that facilitate ratiometric pH sensing, wherein the dye is further associated with a glucose binding moiety and configured to generate a signal that varies in intensity with the concentration of glucose.
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: March 17, 2015
    Assignee: Medtronic Minimed, Inc.
    Inventors: David R. Markle, Jeff T. Suri, Ritchie A. Wessling, Matthew A. Romey
  • Patent number: 8940544
    Abstract: Analyte sensors having antioxidant protection are disclosed. By combining antioxidant and/or scavenger agents into polymer matrices that contain sensor moieties, the sensor moieties are protected from reactive oxygen species. Also disclosed are methods of making analyte sensors and methods of inhibiting oxidative degradation of sensing components in hydrated, polymerized analyte sensor systems.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: January 27, 2015
    Assignee: Medtronic Minimed, Inc.
    Inventors: Jeff T. Suri, Ritchie A. Wessling, Thomas A. Peyser, Soya Gamsey, Eric E. Patterson
  • Publication number: 20140242710
    Abstract: Methods of covalently attaching heparin to a membrane comprising plasma treating the membrane to produce an amino-functionalized membrane; and reacting the amino-functionalized membrane with heparin under conditions in which heparin becomes covalently attached to the amino-functionalized membrane, wherein said heparin is indirectly attached via a spacer to said amino-functionalized membrane and/or said heparin is attached from a single site in said heparin to a single site on said amino-functionalized membrane or to said spacer. Also disclosed are analyte sensors.
    Type: Application
    Filed: September 25, 2012
    Publication date: August 28, 2014
    Inventors: Jeff T. Suri, Eric Patterson
  • Publication number: 20140058225
    Abstract: Embodiments of the present invention are directed to an optical sensor capable of measuring two analytes simultaneously with a single indicator system. In preferred embodiments, the sensor comprises a fluorescent dye having acid and base forms that facilitate ratiometric pH sensing, wherein the dye is further associated with a glucose binding moiety and configured to generate a signal that varies in intensity with the concentration of glucose.
    Type: Application
    Filed: July 25, 2013
    Publication date: February 27, 2014
    Applicant: GluMetrics, Inc.
    Inventors: David R. Markle, Jeff T. Suri, Ritchie A. Wessling, Matthew A. Romey
  • Patent number: 8498682
    Abstract: Embodiments of the present invention are directed to an optical sensor capable of measuring two analytes simultaneously with a single indicator system. In preferred embodiments, the sensor comprises a fluorescent dye having acid and base forms that facilitate ratiometric pH sensing, wherein the dye is further associated with a glucose binding moiety and configured to generate a signal that varies in intensity with the concentration of glucose.
    Type: Grant
    Filed: July 2, 2010
    Date of Patent: July 30, 2013
    Assignee: GluMetrics, Inc.
    Inventors: David R Markle, Jeff T Suri, Ritchie A Wessling, Matthew A Romey
  • Patent number: 8202731
    Abstract: Novel fluorescent dyes are disclosed for use in analyte detection. In particular, mono- and bis-substituted HPTS dyes and methods of making them are provided.
    Type: Grant
    Filed: June 3, 2010
    Date of Patent: June 19, 2012
    Assignee: Glumetrics, Inc.
    Inventor: Jeff T. Suri
  • Publication number: 20110236989
    Abstract: Analyte sensors having antioxidant protection are disclosed. By combining antioxidant and/or scavenger agents into polymer matrices that contain sensor moieties, the sensor moieties are protected from reactive oxygen species. Also disclosed are methods of making analyte sensors and methods of inhibiting oxidative degradation of sensing components in hydrated, polymerized analyte sensor systems.
    Type: Application
    Filed: February 7, 2011
    Publication date: September 29, 2011
    Applicant: GLUMETRICS, INC.
    Inventors: JEFF T. SURI, RITCHIE A. WESSLING, THOMAS A. PEYSER, SOYA GAMSEY, ERIC E. PATTERSON
  • Publication number: 20100279424
    Abstract: Novel fluorescent dyes are disclosed for use in analyte detection. In particular, mono- and bis-substituted HPTS dyes and methods of making them are provided.
    Type: Application
    Filed: June 3, 2010
    Publication date: November 4, 2010
    Applicant: GLUMETRICS INC.
    Inventor: JEFF T. SURI
  • Patent number: 7824918
    Abstract: Novel fluorescent dyes are disclosed for use in analyte detection. In particular, mono- and bis-substituted HPTS dyes and methods of making them are provided.
    Type: Grant
    Filed: August 6, 2008
    Date of Patent: November 2, 2010
    Assignee: Glumetrics, Inc.
    Inventor: Jeff T. Suri
  • Publication number: 20100274110
    Abstract: Embodiments of the present invention are directed to an optical sensor capable of measuring two analytes simultaneously with a single indicator system. In preferred embodiments, the sensor comprises a fluorescent dye having acid and base forms that facilitate ratiometric pH sensing, wherein the dye is further associated with a glucose binding moiety and configured to generate a signal that varies in intensity with the concentration of glucose.
    Type: Application
    Filed: July 2, 2010
    Publication date: October 28, 2010
    Applicant: GluMetrics, Inc
    Inventors: David R. Markle, Jeff T. Suri, Ritchie A. Wessling, Matthew A. Romey