Abstract: This invention relates to a low loss liquid processing system used for manufacturing personal care and cleaning compositions, in particular oral care compositions such as dentifrice, mouthrinse and denture care products. The present process addresses manufacturing flexibility issues involved in making products to demand and the ability to proactively monitor intermediate compositions for quality assurance purposes. Specifically, the present manufacturing process provides faster variant turnaround times, shorter clean-up times between variants, significant material waste reduction and smaller effluent volumes than those of typical batch systems. As well, a process has been developed for more efficient addition of materials which are dissimilar in chemical composition and/or physical parameters to the original base material or of materials which may be temperature and shear sensitive.