Abstract: A system for clipping tissue includes a clip having first and second jaws. Each of the first and second jaws defines an opening through which a control wire passes. A collapsible member is coupled between the first and second jaws. The member is biased to urge the first and second jaws away from one another along an axis of the control wire to a first expanded configuration. The first and second jaws are movable against the bias of the member via the control wire to a second contracted configuration in which the first and second jaws are moved along the axis of the control wire toward one another to lockingly engage tissue received therebetween. The movement of control wire causes a corresponding movement of the first jaw relative to the second jaw to move the first and second jaws from the first expanded configuration to the second contracted configuration.